Chapter 7 (Psychotic Disorders)
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Questions and Answers

What is the primary term used by Bleuler to describe the mental disorder that involves a split in the mind?

  • Paranoia
  • Bipolar disorder
  • Schizophrenia (correct)
  • Dementia praecox
  • What did Kraeplin associate with the concept of 'dementia praecox'?

  • A temporary psychotic episode
  • Early onset mental decline in young individuals (correct)
  • A mental decline in older adults
  • A split personality disorder
  • Which of the following describes the 'first rank symptoms' as argued by Schneider?

  • Symptoms that are exclusively physical in nature
  • Symptoms that are only present in schizophrenia (correct)
  • Symptoms that are evident in mood disorders
  • Symptoms that are common in all psychotic disorders
  • Which of the following is NOT covered in the learning objectives regarding psychotic disorders?

    <p>Historical treatments of psychosis</p> Signup and view all the answers

    According to historical conceptualizations, what is the significance of the term schizophrenia?

    <p>It characterizes a split mind condition.</p> Signup and view all the answers

    What is the relationship between high expressed emotion and relapse in patients?

    <p>High expressed emotion is strongly linked to relapse.</p> Signup and view all the answers

    Which of the following is commonly associated with people experiencing psychosis?

    <p>High suicide rates</p> Signup and view all the answers

    What may exacerbate symptoms in individuals with psychosis?

    <p>Substance abuse</p> Signup and view all the answers

    What type of delusion involves an individual believing that they are under the influence of an external force?

    <p>Delusion of being controlled</p> Signup and view all the answers

    What is a somatic delusion primarily concerned with?

    <p>The appearance or functioning of one's body</p> Signup and view all the answers

    How does psychosis affect the quality of life for individuals?

    <p>40-50 percent are unemployed.</p> Signup and view all the answers

    Which type of delusion is characterized by believing one's partner is unfaithful?

    <p>Delusional jealousy</p> Signup and view all the answers

    Which myth about psychosis contributes to stigma?

    <p>Individuals with psychosis are at increased risk of violence.</p> Signup and view all the answers

    Which type of delusion involves the belief that one's thoughts are being broadcast externally?

    <p>Thought broadcasting</p> Signup and view all the answers

    In which type of delusion does the individual think that events or objects have personal significance?

    <p>Delusion of reference</p> Signup and view all the answers

    In which disorder are delusions related to unjustified guilt and perceived bodily changes primarily found?

    <p>Depressive disorders</p> Signup and view all the answers

    What is the defining characteristic of a grandiose delusion?

    <p>Inflated sense of self-worth and power</p> Signup and view all the answers

    Which delusion is focused on believing one is being conspired against?

    <p>Persecutory delusion</p> Signup and view all the answers

    What key feature is associated with psychotic disorders?

    <p>Disorganized thinking</p> Signup and view all the answers

    What type of delusion is characterized by the belief that thoughts are not one's own but inserted by an external source?

    <p>Thought insertion</p> Signup and view all the answers

    What differentiates a bizarre delusion from other types of delusions?

    <p>It involves beliefs that are considered totally implausible within a culture</p> Signup and view all the answers

    Which type of delusion would likely involve thinking a famous person is in love with the individual?

    <p>Erotomanic delusion</p> Signup and view all the answers

    Which of the following is not a stereotypical delusion found in schizophrenia?

    <p>Grandiosity</p> Signup and view all the answers

    How do ideas of reference differ from delusions of reference?

    <p>Ideas of reference are less unshakeable and organized</p> Signup and view all the answers

    In delusional disorder, which belief is typical?

    <p>Being loved by a high-status individual</p> Signup and view all the answers

    How are hallucinations defined?

    <p>Sensory perceptions that occur without external stimulation</p> Signup and view all the answers

    What differentiates hallucinations from illusions?

    <p>Hallucinations occur without any external stimuli.</p> Signup and view all the answers

    Which type of hallucination involves the perception of taste?

    <p>Gustatory</p> Signup and view all the answers

    Are auditory hallucinations limited to sounds perceived as external?

    <p>No, they can also be perceived as internal sounds.</p> Signup and view all the answers

    Which of the following statements is true concerning insights into hallucinations?

    <p>Some individuals may believe their hallucinations are real.</p> Signup and view all the answers

    Transient hallucinatory experiences can occur in which of the following groups?

    <p>People without a mental disorder</p> Signup and view all the answers

    Which of the following is classified as a somatic hallucination?

    <p>Feeling a sensation of electricity in the body</p> Signup and view all the answers

    Perceptions of odors like burning rubber are classified as which type of hallucination?

    <p>Olfactory</p> Signup and view all the answers

    In which scenario is the term 'hallucination' not generally applied?

    <p>While dreaming</p> Signup and view all the answers

    What is the concordance rate for identical twins (MZ) suffering from schizophrenia according to the studies reviewed?

    <p>48%</p> Signup and view all the answers

    What percentage of individuals diagnosed with schizophrenia have neither parent diagnosed with the disorder?

    <p>89%</p> Signup and view all the answers

    Which disorder shows the highest twin concordance rate based on the provided studies?

    <p>Huntington’s Disease</p> Signup and view all the answers

    What was the concordance rate for dizygotic twins (DZ) with schizophrenia according to Gottesman's review?

    <p>17%</p> Signup and view all the answers

    What type of twins show a higher concordance rate for schizophrenia?

    <p>Monozygotic twins</p> Signup and view all the answers

    In the context of schizophrenia, what does a higher concordance rate suggest about the influence of genetics?

    <p>It suggests a strong genetic influence.</p> Signup and view all the answers

    What does the study of the Genain quadruplets illustrate in the context of schizophrenia?

    <p>Genetic factors can interplay with environmental factors.</p> Signup and view all the answers

    Which of the following is the main focus of study when discussing the aetiology of schizophrenia?

    <p>Genetic factors</p> Signup and view all the answers

    In epidemiological studies, what is the general finding regarding family history in those diagnosed with schizophrenia?

    <p>Few have first-degree relatives with the disorder.</p> Signup and view all the answers

    What kind of studies are primarily relied upon to assess the genetic factors in schizophrenia?

    <p>Family and twin genetic studies</p> Signup and view all the answers

    Which statement correctly summarizes the findings regarding schizophrenia's genetic factors?

    <p>Both genetic and environmental influences play a part.</p> Signup and view all the answers

    How does higher disturbance in the proband relate to twin studies on schizophrenia?

    <p>It correlates with higher concordance rates.</p> Signup and view all the answers

    Which of the following disorders had the lowest concordance rate among dizygotic twins according to the data?

    <p>Schizophrenia</p> Signup and view all the answers

    From the provided studies, which disorder has a direct comparison illustrating divergence in twin types?

    <p>Down’s Syndrome</p> Signup and view all the answers

    Study Notes

    • This material is reproduced and communicated by or on behalf of the University of South Australia, according to section 113P of the Copyright Act 1968.
    • The material may be subject to copyright under the act.
    • Further reproduction is also subject to copyright protection under the act.

    Chapter 7: Psychotic Disorders

    • This chapter discusses psychotic disorders.

    Learning Objectives

    • Outline the defining symptoms of psychosis.
    • Describe the symptoms of DSM-5 psychotic disorders and problems associated with psychosis.
    • Explain the evolution of schizophrenia diagnostic criteria and controversies surrounding the diagnosis.
    • Outline the prevalence, age of onset, and stages of psychosis.
    • Describe the various factors involved in the aetiology of psychosis.
    • Describe main treatment priorities and evidence-based treatment options in relation to psychosis phases.

    Historical Conceptualisations of Psychotic Disorders

    • Kraeplin identified 'dementia praecox', meaning 'senility of the young'.
    • Bleuler coined the term 'schizophrenia' meaning 'split mind'.
    • Schneider argued for 'first rank symptoms' that were specific to schizophrenia.

    Schizophrenia(s)

    • Eugen Bleuler noted that schizophrenia involved various diseases.

    DSM-5 Types of Psychotic Disorders

    • Schizophrenia: At least one month of two or more of the following: delusions, hallucinations, disorganized speech, grossly disorganized/catatonic behaviour, and/or negative symptoms. The disturbance must last at least six months.
    • Schizotypal disorder: Pervasive social and interpersonal deficits and cognitive/perceptual distortions and eccentricities of behaviour beginning before early adulthood.
    • Schizophreniform disorder: Equivalent to schizophrenia but with a shorter disturbance (one to six months).
    • Schizoaffective disorder: Co-occurrence of schizophrenia and a major mood episode, with at least a two-week period of delusions or hallucinations without mood disturbance. Mood symptoms are present for most of the illness duration.
    • Delusional disorder: At least one month of delusions.
    • Brief psychotic disorder: A psychotic disturbance lasting between one day and a month and returning to premorbid functioning.
    • Psychotic disorder due to another medical condition: Prominent hallucinations or delusions resulting from another medical condition.
    • Substance/medication-induced psychotic disorder: Hallucinations or delusions arising from substance intoxication or withdrawal.
    • Other specified schizophrenia spectrum and other psychotic disorder: Symptoms of psychosis causing distress or impairment but not fully meeting criteria for another psychotic disorder.
    • Unspecified schizophrenia spectrum and other psychotic disorder: Symptoms of psychosis causing distress or impairment but not meeting criteria of any psychotic disorder (no specific reasons are provided).

    Key Features of the Psychotic Disorders

    • Delusions
    • Hallucinations
    • Disorganized Thinking
    • Disorganized or Abnormal Motor Behaviour
    • Negative Symptoms

    Principal Psychotic Experiences: Delusions

    • Firmly held beliefs opposed to reality but maintained despite contrary evidence.

    Principal Psychotic Experiences: Hallucinations

    • Perceptual experiences involving perceiving something that is not there (positive) or not perceiving something that is there (negative).

    Kinds of Delusions

    • Bizarre: Implausible according to the person's culture.
    • Delusional jealousy: Delusion that relational partner is unfaithful.
    • Erotomanic: Delusion that another person is in love.
    • Grandiose: Delusion of inflated worth, power, knowledge, identity, or special relationship to a deity.

    Kinds of Delusions

    • of being controlled: Experiences of actions, thoughts, or impulses being controlled by an external force.
    • of Reference: Delusion that events or objects have special significance to the individual.
    • Persecutory: Delusion that one (or someone close) is being attacked, harassed, cheated, persecuted, or conspired against.
    • Somatic: Delusions related to body appearance or functioning.
    • Thought broadcasting: Delusion that one's thoughts are being heard by others.
    • Thought insertion: Delusion that thoughts are not one's own, but rather are inserted into one's mind.

    Delusional Content in Various Disorders

    • Schizophrenia (examples of various contents)
    • Depressive disorders (examples of various contents)
    • Bipolar disorders (mania)(examples of various contents)
    • Delusional disorder (examples of various contents)

    Kinds of Hallucinations

    • Auditory: Perception of sounds (most commonly voices).
    • Gustatory: Perception of taste (usually unpleasant).
    • Olfactory: Perception of odours.
    • Somatic: Perception of physical sensations in the body.
    • Tactile: Perception of touch or something crawling on skin.
    • Visual: Perception of images, flashes of light, or people.

    Disorganised Thinking in Psychotic Disorders

    • Disorganisation
    • Loosening of associations
    • Confusion
    • Disturbances in logical sequencing

    DSM-5 Schizophrenia Spectrum and Other Psychotic Disorders (List)

    • Schizophrenia
    • Schizophreniform disorder
    • Brief psychotic disorder
    • Schizoaffective disorder
    • Delusional disorder
    • Schizotypal (personality) disorder
    • Substance-induced psychotic disorder
    • Psychotic disorder due to a medical condition

    DSM-5-TR Diagnostic Criteria for Schizophrenia

    • Two or more of the following, present for a significant portion of one-month period.
    • Delusions
    • Hallucinations
    • Disorganized speech
    • Grossly disorganized or catatonic behavior
    • Negative symptoms
    • Marked below premorbid functioning in at least one aspect of life.
    • Must have continuous signs lasting at least 6 months

    DSM-5-TR: Schizophreniform Disorder

    • Similar to schizophrenia, but with a shorter episode (at least 1 month but not exceeding 6 months).

    DSM-5-TR: Brief Psychotic Disorder

    • Psychotic symptoms that last at least one day but less than one month.
    • Return to premorbid level of functioning.

    DSM-5-TR Diagnostic Criteria for Schizoaffective Disorder

    • Major mood episode (depression or mania) concurrently with schizophrenia symptoms.
    • Symptoms of delusions or hallucinations should be present for a period without mood episode

    DSM-5-TR Diagnostic Criteria for Delusional Disorder

    • One or more delusions lasting at least one month.
    • Criterion A for schizophrenia has never been met.
    • Functioning is not markedly impaired, and the behavior is not bizarre or odd.

    Subtypes of Delusional Disorder

    • Erotomanic
    • Grandiose
    • Jealous
    • Persecutory
    • Somatic

    Epidemiology of Schizophrenia

    • Lifetime prevalence is approximately 1-2%
    • Men are slightly more affected than women.
    • Increased prevalence rate in developed nations and urban settings.
    • Onset typically during late adolescence and early adulthood.

    Epidemiology of Schizophrenia: Course

    • Premorbid phase: Period before symptoms.
    • Prodromal phase: Period before onset of full symptoms.
    • Acute phase: Active positive and negative symptoms.
    • Early recovery phase: Reduction in depressive or anxious symptoms.
    • Later recovery: Challenges with reintegration into social, recreational, and vocational pursuits.

    Epidemiology of Schizophrenia: Associated Features

    • Depression is often prevalent in patients with psychosis.
    • High rates of suicide attempts are common in psychotic disorders.
    • Anxiety and trauma-related problems are common
    • Substance abuse is a common aspect of psychosis

    Aetiology of Schizophrenia: Genetic Research

    • Genetic factors don't fully explain the disorder.
    • Diathesis-stress model: Genetic predisposition + stress triggers onset.
    • Possible genetic heterogeneity among individuals.

    Aetiology of Schizophrenia: Neurotransmitters

    • Dopamine theory (excess dopamine levels; drugs that reduce dopamine activity may reduce symptoms but takes a while.)
    • Revised dopamine theory (excess number of dopamine receptors or overly sensitive receptors; dopamine abnormalities related to positive symptoms)

    Aetiology of Schizophrenia: Brain Structure and Function

    • Enlarged ventricles.
    • Reduced activity in prefrontal cortex.
    • Developmental factors (prefrontal cortex matures in adolescence).
    • Stress activates HPA system (increasing cortisol and dopamine activity).

    Treatment of Schizophrenia: Medications

    • First-generation antipsychotics (Phenothiazines, butyrophenones).
    • Second-generation antipsychotics (Clozapine, olanzapine,risperidone.)
    • Newer medications may improve cognitive function.

    Treatment of Schizophrenia: Psychological Approaches

    • Patient Outcomes Research Team (PORT) recommendations.
    • Social skills training, and cognitive behavioral therapy.
    • Family therapy to reduce expressed emotion.
    • Treatments with a focus on reducing relapse.

    Treatment of Schizophrenia: Prodromal Phase

    • Emphasis on early detection and intensive intervention to prevent progression.
    • Evidence for use of antipsychotics combined with CBT.

    Treatment of Schizophrenia: Acute Phase

    • Needs 24-hour access to treatment (hospitalisation).
    • Pharmacological approaches (antipsychotics).
    • Psychosocial approaches (addressing co-morbidities).

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