Podcast
Questions and Answers
Which type of crystal solvate is stable and difficult to desolvate because the solvent plays a key role in holding the crystal together?
Which type of crystal solvate is stable and difficult to desolvate because the solvent plays a key role in holding the crystal together?
- Polymorphic solvate (correct)
- Anhydrate
- Monohydrate
- Pseudopolymorphic solvate
What term is used to describe crystals that contain solvent of crystallization?
What term is used to describe crystals that contain solvent of crystallization?
- Hydrate (correct)
- Monohydrate
- Anhydrate
- Pseudopolymorphic solvate
If a crystal loses its solvent and recrystallizes in a new form, it is likely a:
If a crystal loses its solvent and recrystallizes in a new form, it is likely a:
- Pseudopolymorphic solvate (correct)
- Monohydrate
- Hydrate
- Anhydrate
What is the term for a crystal that does not contain any water within its structure?
What is the term for a crystal that does not contain any water within its structure?
Which type of crystal solvate typically has a complex dissolution rate due to its structure and composition?
Which type of crystal solvate typically has a complex dissolution rate due to its structure and composition?
What happens to pseudopolymorphic solvates when desolvation occurs?
What happens to pseudopolymorphic solvates when desolvation occurs?
How do the physicochemical properties of solvated forms differ from anhydrous forms?
How do the physicochemical properties of solvated forms differ from anhydrous forms?
What is typically true about the melting point comparison between anhydrous crystals and hydrates?
What is typically true about the melting point comparison between anhydrous crystals and hydrates?
How does the dissolution rate of hydrates compared to anhydrous forms vary?
How does the dissolution rate of hydrates compared to anhydrous forms vary?
Why can some hydrates have a slower dissolution rate than anhydrous forms?
Why can some hydrates have a slower dissolution rate than anhydrous forms?
What is the main purpose of pharmaceutical co-crystals?
What is the main purpose of pharmaceutical co-crystals?
Which type of polymorph can be reversibly changed to another form by varying temperature and pressure?
Which type of polymorph can be reversibly changed to another form by varying temperature and pressure?
What type of polymorph undergoes irreversible change between two forms?
What type of polymorph undergoes irreversible change between two forms?
Which polymorphic form is selected for solid dosage forms during drug development?
Which polymorphic form is selected for solid dosage forms during drug development?
What type of polymorph has the highest melting temperature and is the least soluble in any solvent?
What type of polymorph has the highest melting temperature and is the least soluble in any solvent?
Which type of crystal habit may make it difficult to inject a polymorph in suspension form or formulate it as a tablet?
Which type of crystal habit may make it difficult to inject a polymorph in suspension form or formulate it as a tablet?
What can crystal growth in creams as a result of phase transformation cause to happen?
What can crystal growth in creams as a result of phase transformation cause to happen?
