PoxViridae L2

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Questions and Answers

Pseudocowpox belongs to which viral genus?

  • Orthopoxvirus
  • Parapoxvirus (correct)
  • Adenovirus
  • Herpesvirus

Which species can be affected by viruses in the Parapoxvirus genus?

  • Only cattle
  • Only humans
  • Cattle, sheep, goats, and humans (correct)
  • Birds and reptiles

What is pseudocowpox commonly called when it infects humans?

  • Cowpox
  • Orf
  • Milkers nodule (correct)
  • Bovine eczema

How is pseudocowpox primarily transmitted?

<p>From infected cattle via direct or indirect contact (B)</p> Signup and view all the answers

Which of the following is NOT a known transmission route of pseudocowpox?

<p>Airborne transmission (D)</p> Signup and view all the answers

How can calves become infected with pseudocowpox?

<p>By sucking on infected teats of cows</p> Signup and view all the answers

In which regions has pseudocowpox been reported?

<p>In most countries worldwide</p> Signup and view all the answers

What is the primary characteristic of pseudocowpox lesions?

<p>Hyperplasia of squamous epithelium (B)</p> Signup and view all the answers

How severe are pseudocowpox infections typically?

<p>Mild (A)</p> Signup and view all the answers

What is the correct sequence of lesion development in pseudocowpox?

<p>Erythema → papule → vesicle or pustule → rupture → thick scab formation (B)</p> Signup and view all the answers

What is the typical size range of the thick scabs formed in pseudocowpox?

<p>0.5 to 25 cm in diameter</p> Signup and view all the answers

Why do the thick scabs in pseudocowpox lesions become elevated?

<p>Due to granulation tissue buildup (B)</p> Signup and view all the answers

After 7–10 days, what is a characteristic feature of the healing pseudocowpox lesion?

<p>A horseshoe-shaped ring of small scabs around a small wart-like granuloma (C)</p> Signup and view all the answers

What is a characteristic feature of chronic pseudocowpox lesions?

<p>Yellow-gray, soft scurfy scabs that are rubbed off during milking (B)</p> Signup and view all the answers

Which of the following is NOT a feature of chronic pseudocowpox?

<p>Painful ulcerative wounds (C)</p> Signup and view all the answers

What happens to the skin in chronic pseudocowpox infections?

<p>It becomes corrugated and thickened (C)</p> Signup and view all the answers

What is the hallmark clinical sign (pathognomonic lesion) of pseudocowpox?

<p>A horseshoe shaped ring of small scabs around a wart-like granuloma</p> Signup and view all the answers

What laboratory methods can confirm a diagnosis of pseudocowpox?

<p>Isolation and detection of the virus from vesicular fluid or teat skin samples (B)</p> Signup and view all the answers

Which of the following diseases is NOT a differential diagnosis for pseudocowpox?

<p>Foot-and-mouth disease (D)</p> Signup and view all the answers

How does udder impetigo differ from pseudocowpox?

<p>Udder impetigo is caused by a bacterial infection, whereas pseudocowpox is viral (A)</p> Signup and view all the answers

Which environmental condition can cause teat lesions that resemble pseudocowpox?

<p>Frostbite and teat chaps (B)</p> Signup and view all the answers

What are the treatment methods for pseudocowpox?

<p>Removal of scabs, burn scabs to prevent environmental contamination, application of an emollient ointment before milking and application of astringement preparation after milking.</p> Signup and view all the answers

What are the prevention methods for psuedocowpox?

<p>Disenfection via iodophor teat dip, isolation and treatment of infected cows, and reduce teat trauma- as injuries to skin of teat predisposes to infection</p> Signup and view all the answers

What are the synonyms for Contagious Ecthyma?

<p>ORF, Scabby mouth, Contagious pustular dermatitis, and sore mouth</p> Signup and view all the answers

Which of the following Genus does Contagious Ecthyma belong to?

<p>Parapoxvirus (A)</p> Signup and view all the answers

Who are the hosts susceptible to ORF/Conotagious Ecthyma?

<p>Shoats, primarily lambs and goat kids (C)</p> Signup and view all the answers

Contagious Ecthyma aka ORF has a worldwide distribution

<p>True (A)</p> Signup and view all the answers

What characteristic of Contagious Ecthyma scabs contributes to its transmission?

<p>They contain a high concentration of the virus. (D)</p> Signup and view all the answers

Why is Contagious Ecthyma able to persist in the environment for extended periods?

<p>The virus remains infectious for a long time under dry conditions. (B)</p> Signup and view all the answers

How do contaminated instruments contribute to the spread of Contagious Ecthyma?

<p>They create skin abrasions, allowing viral entry. (C)</p> Signup and view all the answers

What is the primary route of Contagious Ecthyma infection in healthy animals??

<p>Through damaged skin. (B)</p> Signup and view all the answers

Why are docking instruments and ear-tagging pliers specifically mentioned as potential sources of Contagious Ecthyma transmission?

<p>They often cause skin abrasions, facilitating viral entry. (D)</p> Signup and view all the answers

What is the MOST likely reason Contagious Ecthyma spreads rapidly through a flock of sheep or goats?

<p>The animals are in close contact, facilitating transmission through damaged skin. (D)</p> Signup and view all the answers

If a lamb develops oral lesions, what is the most likely source of the Contagious Ecthyma infection?

<p>Lesions on the mother's teats. (D)</p> Signup and view all the answers

Describe the pathogenesis of Contagious Ecthyma lesions starting from “macule”

<p>The lesions evolve from macule, papule, vesicle, pustule, ulcers and finally scab formation</p> Signup and view all the answers

Where do the first lesions of Contagious Ecthyma (ORF) typically develop?

<p>At the mucocutaneous junction (C)</p> Signup and view all the answers

Which of the following is NOT a common consequence of ORF in affected animals?

<p>Immediate scarring after lesion healing (B)</p> Signup and view all the answers

How long does it take for ORF scabs to drop off and heal?

<p>1-4 weeks (B)</p> Signup and view all the answers

What is a severe complication of ORF due to secondary bacterial infection?

<p>Both A and B (D)</p> Signup and view all the answers

Why should the ORF vaccine NOT be used on farms without an existing ORF problem?

<p>It can introduce the disease into the farm (B)</p> Signup and view all the answers

Where is the ORF vaccine applied on the animal?

<p>Inside the thigh (B)</p> Signup and view all the answers

When should pregnant ewes be vaccinated against ORF?

<p>7-8 weeks before lambing (C)</p> Signup and view all the answers

What is the main sign that an ORF vaccine is viable?

<p>The appearance of a local reaction at the vaccination site (C)</p> Signup and view all the answers

When should you inspect a lamb you’ve vaccinated for ORF to observe any local reactions?

<p>1 week (C)</p> Signup and view all the answers

In humans, where can ORF lesions commonly develop?

<p>Finger, hands and face (C), Arm and penis (D)</p> Signup and view all the answers

Flashcards

Pseudocowpox genus

A viral genus that includes the pseudocowpox virus.

Species affected by Parapoxvirus

Cattle, sheep, goats, and humans.

Pseudocowpox in humans

Milker's nodule

Pseudocowpox transmission

Direct or indirect contact with infected cattle.

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How calves get infected

Sucking on infected teats of cows.

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Pseudocowpox regions

Most countries worldwide.

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Primary characteristic of lesions

Hyperplasia of squamous epithelium.

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Severity of Pseudocowpox

Mild.

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Lesion sequence

Erythema → papule → vesicle or pustule → rupture → thick scab formation.

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Scab size range

0.5 to 25 cm in diameter.

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Why scabs elevate

Due to granulation tissue buildup.

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Healing lesion feature

A horseshoe-shaped ring of small scabs around a small wart-like granuloma.

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Chronic pseudocowpox feature

Yellow-gray, soft scurfy scabs that are rubbed off during milking.

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Skin in chronic infections

The skin becomes corrugated and thickened.

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Pseudocowpox hallmark lesion

A horseshoe shaped ring of small scabs around a wart-like granuloma.

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Diagnosis methods

Isolation and detection of the virus from vesicular fluid or teat skin samples.

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Udder impetigo vs. pseudocowpox

Udder impetigo is caused by a bacterial infection, whereas pseudocowpox is viral.

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Environmental condition that causes teat lesions

Frostbite and teat chaps.

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Non-transmission route

Airborne transmission

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Not a Differential Diagnosis

Foot-and-mouth disease

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Typical Severity

Mild.

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Milker's Nodule

Another name for the pseudocowpox virus in humans, typically contracted by dairy farmers.

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Contagious Ecthyma

A viral disease primarily affecting sheep and goats, especially lambs and kids, characterized by lesions around the mouth.

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ORF virus

The scientific name of the virus that causes contagious ecthyma. It belongs to the genus Parapoxvirus.

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Contagious Ecthyma Host

Sheep and goats, with a higher prevalence and severity observed in young animals like lambs and goat kids.

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Contagious Ecthyma Distribution

Contagious Ecthyma is present globally, affecting sheep and goat populations worldwide.

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Contagious Ecthyma Transmission

Scabs from healing lesions contain the contagious ecthyma virus and can transmit the disease.

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Virus Stability

The contagious ecthyma virus is highly stable and infectious for extended periods, especially in dry conditions.

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Instrument Transmission

Contaminated instruments, such as those used for docking or ear tagging, can transmit the contagious ecthyma virus.

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Speed of Spread

Contagious ecthyma spreads rapidly within a flock due to its highly contagious nature.

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Entry Point

The contagious ecthyma virus infects animals by entering through damaged skin.

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Oral Lesion Transmission

Lambs and kids can develop oral lesions from nursing on dams with teat lesions, and vice versa, spreading contagious ecthyma.

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Study Notes

  • Pseudocowpox in humans manifests as Milker's nodules.
  • Lesions appear on hands of dairy farmers milking teats or vets treating infected cows.
  • Lesions range from multiple vesicles to a single, indurated nodule.

Contagious Ecthyma

  • Also known as ORF, scabby mouth, contagious pustular dermatitis, sore mouth
  • Etiology: ORF virus, genus parapoxvirus
  • Primarily affects sheep and goats, especially lambs and goat kids.
  • Distribution: worldwide
  • Transmission occurs through scabs that fall off healing lesions, as they contain the virus.
  • Viruses are stable in the environment and remain highly infectious for long periods under dry conditions.
  • Contaminated instruments, like docking instruments or ear-tagging pliers, can transmit the virus.
  • Spread in a flock is very rapid.
  • Virus infects healthy animals primarily through damaged skin.
  • Oral lesions in lambs or kids result from nursing dams with teat lesions, and vice versa.

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