Pruritus and its Characteristics

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What is pruritus?

An unpleasant sensation that provokes the desire to scratch

How does the sensation of well-localized pricking itch travel to the sensory cortex?

By ascending through the dorsal column

Which of the following are putative mediators of pruritus?

Leukotrienes and histamines

What is the main difference between myelinated fibers and nonmyelinated fibers in transmitting itch sensations?

Speed of conduction

What is the most effective drug in the management of pruritus?

Glucocorticoids

Which drug provides rapid relief from pruritus and inflammation in dogs with allergic skin disease?

Oclacitinib

What is the most common cause of pruritus in animals according to the text?

Parasites

What is a common adverse effect of cyclosporine modified in controlling pruritus?

Vomiting and diarrhea

Why are glucocorticoids not suitable for longterm management of pruritus?

Owners cannot tolerate the common adverse effects for long periods

What is the most commonly used drug in large animals for mite infestations?

Ivermectin

Which of the following is the next most important group of pruritic diseases to exclude, after mite infestations?

Bacterial infections

What is the recommended topical antimicrobial shampoo therapy for pruritic animals?

2% chlorhexidine/2% miconazole

Which systemic antifungal drug should not be used for pruritic animals?

Terbinafine

What is the standard of care for treating food allergy in pruritic animals?

Hydrolyzed diets

What is the most common cause of allergic pruritus in animals?

Flea allergy dermatitis

What diagnostic testing should be performed to exclude or include food allergy?

Diet trial and provocative challenge

Which type of antipruritic therapy does not have support based on evidence-based reviews?

$Antihistamines$

What is the clinical diagnosis for atopic dermatitis based on?

Clinical features

What causes nonpruritic diseases to become pruritic in animals?

Secondary bacterial or yeast infections

Which drug should be used concurrently with ivermectin in large animals for mite infestations?

Lime sulfur

Test your knowledge about pruritus, the unpleasant sensation within the skin that provokes the desire to scratch. Explore the definition, characteristics, and transmission of this common dermatologic issue in animals.

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