Pruritus and its Characteristics

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Questions and Answers

What is pruritus?

  • A medical diagnosis for skin diseases
  • A type of skin inflammation caused by histamines
  • An unpleasant sensation that provokes the desire to scratch (correct)
  • A specialized pruritus receptor in the skin

How does the sensation of well-localized pricking itch travel to the sensory cortex?

  • Through the lateral spinothalamic tract
  • By ascending through the dorsal column (correct)
  • Via nonmyelinated fibers at 2 m/sec
  • By crossing into the dorsal root of the spinal cord

Which of the following are putative mediators of pruritus?

  • Prostaglandins and thromboxane A2
  • Mast cell degranulation and proteolytic enzymes
  • Leukotrienes and histamines (correct)
  • Myelinated fibers and nonmyelinated fibers

What is the main difference between myelinated fibers and nonmyelinated fibers in transmitting itch sensations?

<p>Speed of conduction (C)</p> Signup and view all the answers

What is the most effective drug in the management of pruritus?

<p>Glucocorticoids (D)</p> Signup and view all the answers

Which drug provides rapid relief from pruritus and inflammation in dogs with allergic skin disease?

<p>Oclacitinib (B)</p> Signup and view all the answers

What is the most common cause of pruritus in animals according to the text?

<p>Parasites (D)</p> Signup and view all the answers

What is a common adverse effect of cyclosporine modified in controlling pruritus?

<p>Vomiting and diarrhea (A)</p> Signup and view all the answers

Why are glucocorticoids not suitable for longterm management of pruritus?

<p>Owners cannot tolerate the common adverse effects for long periods (A)</p> Signup and view all the answers

What is the most commonly used drug in large animals for mite infestations?

<p>Ivermectin (C)</p> Signup and view all the answers

Which of the following is the next most important group of pruritic diseases to exclude, after mite infestations?

<p>Bacterial infections (B)</p> Signup and view all the answers

What is the recommended topical antimicrobial shampoo therapy for pruritic animals?

<p>2% chlorhexidine/2% miconazole (D)</p> Signup and view all the answers

Which systemic antifungal drug should not be used for pruritic animals?

<p>Terbinafine (A)</p> Signup and view all the answers

What is the standard of care for treating food allergy in pruritic animals?

<p>Hydrolyzed diets (D)</p> Signup and view all the answers

What is the most common cause of allergic pruritus in animals?

<p>Flea allergy dermatitis (C)</p> Signup and view all the answers

What diagnostic testing should be performed to exclude or include food allergy?

<p>Diet trial and provocative challenge (A)</p> Signup and view all the answers

Which type of antipruritic therapy does not have support based on evidence-based reviews?

<p>$Antihistamines$ (A)</p> Signup and view all the answers

What is the clinical diagnosis for atopic dermatitis based on?

<p>Clinical features (B)</p> Signup and view all the answers

What causes nonpruritic diseases to become pruritic in animals?

<p>Secondary bacterial or yeast infections (D)</p> Signup and view all the answers

Which drug should be used concurrently with ivermectin in large animals for mite infestations?

<p>Lime sulfur (D)</p> Signup and view all the answers

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