Pruritus and its Characteristics

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What is pruritus?

A medical diagnosis for skin diseases

A type of skin inflammation caused by histamines

An unpleasant sensation that provokes the desire to scratch (correct)

A specialized pruritus receptor in the skin

How does the sensation of well-localized pricking itch travel to the sensory cortex?

Through the lateral spinothalamic tract

By ascending through the dorsal column (correct)

Via nonmyelinated fibers at 2 m/sec

By crossing into the dorsal root of the spinal cord

Which of the following are putative mediators of pruritus?

Prostaglandins and thromboxane A2

Mast cell degranulation and proteolytic enzymes

Leukotrienes and histamines (correct)

Myelinated fibers and nonmyelinated fibers

What is the main difference between myelinated fibers and nonmyelinated fibers in transmitting itch sensations?

Speed of conduction Signup and view all the answers

What is the most effective drug in the management of pruritus?

Glucocorticoids Signup and view all the answers

Which drug provides rapid relief from pruritus and inflammation in dogs with allergic skin disease?

Oclacitinib Signup and view all the answers

What is the most common cause of pruritus in animals according to the text?

Parasites Signup and view all the answers

What is a common adverse effect of cyclosporine modified in controlling pruritus?

Vomiting and diarrhea Signup and view all the answers

Why are glucocorticoids not suitable for longterm management of pruritus?

Owners cannot tolerate the common adverse effects for long periods Signup and view all the answers

What is the most commonly used drug in large animals for mite infestations?

Ivermectin Signup and view all the answers

Which of the following is the next most important group of pruritic diseases to exclude, after mite infestations?

Bacterial infections Signup and view all the answers

What is the recommended topical antimicrobial shampoo therapy for pruritic animals?

2% chlorhexidine/2% miconazole Signup and view all the answers

Which systemic antifungal drug should not be used for pruritic animals?

Terbinafine Signup and view all the answers

What is the standard of care for treating food allergy in pruritic animals?

Hydrolyzed diets Signup and view all the answers

What is the most common cause of allergic pruritus in animals?

Flea allergy dermatitis Signup and view all the answers

What diagnostic testing should be performed to exclude or include food allergy?

Diet trial and provocative challenge Signup and view all the answers

Which type of antipruritic therapy does not have support based on evidence-based reviews?

$Antihistamines$ Signup and view all the answers

What is the clinical diagnosis for atopic dermatitis based on?

Clinical features Signup and view all the answers

What causes nonpruritic diseases to become pruritic in animals?

Secondary bacterial or yeast infections Signup and view all the answers

Which drug should be used concurrently with ivermectin in large animals for mite infestations?

Lime sulfur Signup and view all the answers