Protein Trafficking Week 2 Overview
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Questions and Answers

What is the primary cellular store for calcium within the cell?

  • Golgi apparatus
  • Lysosomes
  • Endoplasmic reticulum (correct)
  • Mitochondria
  • Which organelle is responsible for lipid biosynthesis, including phospholipids and cholesterol, within a cell?

  • Nucleus
  • Lysosomes
  • Mitochondria
  • Endoplasmic reticulum (correct)
  • Where does the nuclear endoplasmic reticulum (nER) enclose DNA?

  • Within the nucleus (correct)
  • Inside the Golgi apparatus
  • Within the lysosomes
  • Between the inner and outer mitochondrial membranes
  • In which type of cell is rough endoplasmic reticulum (ER) more predominant?

    <p>Pancreatic cells</p> Signup and view all the answers

    What is the main characteristic feature of the cortical endoplasmic reticulum (cER)?

    <p>Presence of numerous ribosomes</p> Signup and view all the answers

    Which organelle forms a close relationship with the peripheral endoplasmic reticulum near the plasma membrane?

    <p>Golgi apparatus</p> Signup and view all the answers

    What facilitates the lateral growth of the ER, generating cortical ER?

    <p>Exocyst</p> Signup and view all the answers

    Which proteins are necessary and sufficient to generate ER tubules?

    <p>Reticulons and REEPs</p> Signup and view all the answers

    What plays a role in the dynamic movement of ER tubules along one another?

    <p>Microtubules</p> Signup and view all the answers

    Which organelles are involved in the rapid assembly and disassembly of peripheral sheet-like structures into tubules?

    <p>Endoplasmic reticulum</p> Signup and view all the answers

    Which type of junctions appear to rapidly interconvert between 'sheet-like' structures in the ER dynamics?

    <p>'T' junctions</p> Signup and view all the answers

    What happens ultimately after the nuclear division during ER dynamics?

    <p>Cytokinesis separates the two cells</p> Signup and view all the answers

    What is the main function of the ER mentioned in the text?

    <p>Synthesis and modification of secretory proteins</p> Signup and view all the answers

    Which protein is mentioned to determine the architecture and dynamics of the axonal ER ladder?

    <p>Reticulon 2</p> Signup and view all the answers

    In a polarized migrating cell, where is the ER scattered according to the text?

    <p>Towards the front of the cell</p> Signup and view all the answers

    Which organelle is NOT mentioned as being in contact with the ER according to the text?

    <p>Lysosomes</p> Signup and view all the answers

    What type of vesicles are observed all across a cell in the text?

    <p>Endosomes</p> Signup and view all the answers

    What is the main function of the axonal ER ladder in developing neurons as per the text?

    <p>Trafficking of vesicular axonal cargoes</p> Signup and view all the answers

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