18 Questions
What is the primary cellular store for calcium within the cell?
Endoplasmic reticulum
Which organelle is responsible for lipid biosynthesis, including phospholipids and cholesterol, within a cell?
Endoplasmic reticulum
Where does the nuclear endoplasmic reticulum (nER) enclose DNA?
Within the nucleus
In which type of cell is rough endoplasmic reticulum (ER) more predominant?
Pancreatic cells
What is the main characteristic feature of the cortical endoplasmic reticulum (cER)?
Presence of numerous ribosomes
Which organelle forms a close relationship with the peripheral endoplasmic reticulum near the plasma membrane?
Golgi apparatus
What facilitates the lateral growth of the ER, generating cortical ER?
Exocyst
Which proteins are necessary and sufficient to generate ER tubules?
Reticulons and REEPs
What plays a role in the dynamic movement of ER tubules along one another?
Microtubules
Which organelles are involved in the rapid assembly and disassembly of peripheral sheet-like structures into tubules?
Endoplasmic reticulum
Which type of junctions appear to rapidly interconvert between 'sheet-like' structures in the ER dynamics?
'T' junctions
What happens ultimately after the nuclear division during ER dynamics?
Cytokinesis separates the two cells
What is the main function of the ER mentioned in the text?
Synthesis and modification of secretory proteins
Which protein is mentioned to determine the architecture and dynamics of the axonal ER ladder?
Reticulon 2
In a polarized migrating cell, where is the ER scattered according to the text?
Towards the front of the cell
Which organelle is NOT mentioned as being in contact with the ER according to the text?
Lysosomes
What type of vesicles are observed all across a cell in the text?
Endosomes
What is the main function of the axonal ER ladder in developing neurons as per the text?
Trafficking of vesicular axonal cargoes
Learn about the structure and functions of the Endoplasmic Reticulum (ER) in protein trafficking. The course taught by Guillaume Thibault emphasizes understanding concepts rather than memorization for the final exam.
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