Protein Trafficking Week 2 Overview

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Questions and Answers

What is the primary cellular store for calcium within the cell?

  • Golgi apparatus
  • Lysosomes
  • Endoplasmic reticulum (correct)
  • Mitochondria

Which organelle is responsible for lipid biosynthesis, including phospholipids and cholesterol, within a cell?

  • Nucleus
  • Lysosomes
  • Mitochondria
  • Endoplasmic reticulum (correct)

Where does the nuclear endoplasmic reticulum (nER) enclose DNA?

  • Within the nucleus (correct)
  • Inside the Golgi apparatus
  • Within the lysosomes
  • Between the inner and outer mitochondrial membranes

In which type of cell is rough endoplasmic reticulum (ER) more predominant?

<p>Pancreatic cells (A)</p> Signup and view all the answers

What is the main characteristic feature of the cortical endoplasmic reticulum (cER)?

<p>Presence of numerous ribosomes (C)</p> Signup and view all the answers

Which organelle forms a close relationship with the peripheral endoplasmic reticulum near the plasma membrane?

<p>Golgi apparatus (A)</p> Signup and view all the answers

What facilitates the lateral growth of the ER, generating cortical ER?

<p>Exocyst (B)</p> Signup and view all the answers

Which proteins are necessary and sufficient to generate ER tubules?

<p>Reticulons and REEPs (D)</p> Signup and view all the answers

What plays a role in the dynamic movement of ER tubules along one another?

<p>Microtubules (A)</p> Signup and view all the answers

Which organelles are involved in the rapid assembly and disassembly of peripheral sheet-like structures into tubules?

<p>Endoplasmic reticulum (B)</p> Signup and view all the answers

Which type of junctions appear to rapidly interconvert between 'sheet-like' structures in the ER dynamics?

<p>'T' junctions (A)</p> Signup and view all the answers

What happens ultimately after the nuclear division during ER dynamics?

<p>Cytokinesis separates the two cells (D)</p> Signup and view all the answers

What is the main function of the ER mentioned in the text?

<p>Synthesis and modification of secretory proteins (D)</p> Signup and view all the answers

Which protein is mentioned to determine the architecture and dynamics of the axonal ER ladder?

<p>Reticulon 2 (C)</p> Signup and view all the answers

In a polarized migrating cell, where is the ER scattered according to the text?

<p>Towards the front of the cell (C)</p> Signup and view all the answers

Which organelle is NOT mentioned as being in contact with the ER according to the text?

<p>Lysosomes (A)</p> Signup and view all the answers

What type of vesicles are observed all across a cell in the text?

<p>Endosomes (A)</p> Signup and view all the answers

What is the main function of the axonal ER ladder in developing neurons as per the text?

<p>Trafficking of vesicular axonal cargoes (C)</p> Signup and view all the answers

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