Protein Structure and Function 2 (Lec 8) (Set 1)
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Questions and Answers

Which level of protein structure is determined by the sequence of amino acids in the polypeptide chain?

  • Quaternary structure
  • Primary structure (correct)
  • Secondary structure
  • Tertiary structure
  • Which type of fibrous protein is formed by the arrangement of protein chains into fibres?

  • Triple helix
  • Coiled-coil
  • Collagen (correct)
  • β-sheets
  • What is the primary structure of α-keratin characterized by?

  • Antiparallel β-sheets
  • Triple helix structure
  • Glycine-rich repeat (correct)
  • Coiled-coil structure
  • How do the β-sheets in fibroin interact with each other?

    <p>Van der Waals bonds</p> Signup and view all the answers

    What is the most abundant vertebrate protein?

    <p>Collagen</p> Signup and view all the answers

    Which amino acid is frequently found in the repeating tripeptide sequence of collagen?

    <p>Glycine</p> Signup and view all the answers

    How do the polypeptide chains in collagen form inter-chain bonds?

    <p>Hydrogen bonds</p> Signup and view all the answers

    Which type of bond is responsible for the formation of tertiary structure in proteins?

    <p>B C D</p> Signup and view all the answers

    What is the function of disulphide bridges in proteins?

    <p>To stabilize the tertiary structure</p> Signup and view all the answers

    How are alpha-helices usually represented in diagrammatic representations of tertiary structure?

    <p>As spirals or cylinders within the ribbon</p> Signup and view all the answers

    What is the primary role of non-covalent bonds in tertiary structure formation?

    <p>To maintain the overall protein structure</p> Signup and view all the answers

    Which level of protein structure is responsible for the association of secondary structures into compact domains?

    <p>Tertiary structure</p> Signup and view all the answers

    What is the function of quaternary structure in proteins?

    <p>To form proteins from multiple polypeptide chains</p> Signup and view all the answers

    What makes proteins more resistant to degradation and denaturation?

    <p>Disulphide bridges</p> Signup and view all the answers

    What is the primary component shown in diagrammatic representations of tertiary structure?

    <p>Polypeptide backbone</p> Signup and view all the answers

    Which type of bond is NOT involved in the formation of tertiary structure in proteins?

    <p>Disulphide bridges</p> Signup and view all the answers

    Quaternary structure refers to the arrangement of protein chains into fibres.

    <p>False</p> Signup and view all the answers

    Globular proteins are usually involved in structural roles within the cell.

    <p>False</p> Signup and view all the answers

    The primary structure of a protein is determined by the position of disulphide cross-links.

    <p>False</p> Signup and view all the answers

    Keratin is a fibrous protein that forms strong fibres in skin, bone, teeth, etc.

    <p>False</p> Signup and view all the answers

    Collagen forms a triple helix structure, with every 4th amino acid passing through the center.

    <p>False</p> Signup and view all the answers

    True or false: Tertiary structure refers to the association of secondary structures into compact domains.

    <p>True</p> Signup and view all the answers

    True or false: covalent bonds, hydrogen bonds and van der Waals forces, play a crucial role in the correct formation of tertiary structure.

    <p>False</p> Signup and view all the answers

    True or false: Disulphide bridges are covalent bonds that can form between the side chains of cysteine residues, making proteins more resistant to degradation and denaturation.

    <p>True</p> Signup and view all the answers

    True or false: Diagrammatic representations of tertiary structure usually only show the polypeptide backbone, with alpha-helices represented as spirals or cylinders, and beta-strands represented as arrows.

    <p>True</p> Signup and view all the answers

    True or false: Quaternary structure refers to proteins that are formed from more than one polypeptide chain.

    <p>True</p> Signup and view all the answers

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