Protein Structure Hierarchies Quiz

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Which amino acid disrupts the α-helix due to its secondary amino group not being geometrically compatible with the spiral of the helix?

Tryptophan

Proline (correct)

Valine

Isoleucine

What type of interactions do charged amino acids form in the context of disrupting the α-helix?

Covalent bonds

Ionic interactions (correct)

Hydrogen bonds

Peptide bonds

Which secondary structure of proteins involves two or more polypeptide chains in an almost fully extended form?

α-helix

Turn

β-sheet (correct)

Coil

What type of β-sheet arrangement has polypeptide chains arranged with N- and C-termini alternating?

Antiparallel sheets Signup and view all the answers

What type of bonds form between the polypeptide backbones of separate polypeptide chains in the context of β-sheet formation?

Hydrogen bonds Signup and view all the answers

Which amino acid with bulky side chains interferes with the helical structure if present in large numbers?

Tryptophan Signup and view all the answers

What is the primary structure of proteins defined as?

The sequence of amino acids in a protein Signup and view all the answers

What is the name for the amide link between the α carboxyl group of one amino acid and the α-amino group of another?

Peptide bond Signup and view all the answers

What is the N-terminal of a peptide chain?

The free amino end Signup and view all the answers

What characteristic gives the peptide bond a partial double bond character?

Rigidity and planarity Signup and view all the answers

What type of structure is formed when a polypeptide chain forms a spiral structure with amino acid side chains extending outward?

α-helix Signup and view all the answers

What stabilizes the α-helix structure through hydrogen bonding?

Peptide-bond carbonyl oxygens and amide hydrogens Signup and view all the answers

How many residues are linked through hydrogen bonds in each turn of the α-helix?

4 Signup and view all the answers

What does quaternary structure of proteins refer to?

The arrangement of multiple polypeptide chains in a protein complex. Signup and view all the answers

Which end of the peptide chain is written to the left, and which is written to the right?

N-terminal to the left, C-terminal to the right Signup and view all the answers

What are the only charged groups on a polypeptide?

N-terminal α- amino group, C- terminal α- carboxyl group, ionized groups in side chains of amino acids. Signup and view all the answers

Protein Structure Hierarchies Quiz

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