Protein Structure and Function

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Questions and Answers

What can form a diffusion barrier similar to the nuclear pore?

  • A network of polypeptide chains with disulfide bonds
  • A dense network of unstructured proteins (correct)
  • A network of hexagonally packed globular protein subunits
  • A dense network of structured proteins

What type of bonds form between adjacent cysteine side chains?

  • Covalent disulfide bonds (correct)
  • Hydrogen bonds
  • Peptide bonds
  • Ionic bonds

What is a common feature of protein assemblies?

  • Multiple protein-protein contacts (correct)
  • Multiple protein-ligand contacts
  • Multiple protein-nucleic acid contacts
  • Multiple protein-membrane contacts

What is the shape of the protein coat or capsid of many simple viruses?

<p>A hollow sphere based on an icosahedron (B)</p> Signup and view all the answers

What is the function of the capsid in viral structures?

<p>To enclose and protect the viral nucleic acid (C)</p> Signup and view all the answers

What is a characteristic of protein subunits in viral capsids?

<p>They are composed of identical protein molecules (C)</p> Signup and view all the answers

What is the approximate diameter of the tomato bushy stunt virus (TBSV)?

<p>33 nm (B)</p> Signup and view all the answers

How many identical copies of the capsid protein are present in the TBSV?

<p>180 (C)</p> Signup and view all the answers

What is the purpose of the proteolytic enzyme in insulin assembly?

<p>To cleave the proinsulin into insulin after it has folded into a specific shape (A)</p> Signup and view all the answers

What is the function of the short amyloid fibrils formed by peptide hormones of the endocrine system?

<p>To store the hormones in an inactive form (C)</p> Signup and view all the answers

What is the name of the extensively studied yeast prion protein?

<p>Sup35 (C)</p> Signup and view all the answers

What type of bonds are disrupted in the insulin protein that cannot spontaneously re-form efficiently?

<p>Disulfide bonds (C)</p> Signup and view all the answers

What is the shape of a typical antibody molecule?

<p>Y-shaped (B)</p> Signup and view all the answers

What happens when colliding molecules have poorly matching surfaces?

<p>They form few noncovalent bonds (B)</p> Signup and view all the answers

What is a characteristic of enzymes within a functional class?

<p>They are highly specific and catalyze a single type of reaction (A)</p> Signup and view all the answers

What happens to the rate of reaction when the enzyme molecule is saturated with substrate?

<p>It reaches a maximum value (C)</p> Signup and view all the answers

What does the Km of an enzyme represent?

<p>The concentration of substrate that allows the reaction to proceed at half its maximum rate (D)</p> Signup and view all the answers

How do enzymes accelerate chemical reactions?

<p>By decreasing the activation energy (D)</p> Signup and view all the answers

What is the role of lysozyme in the catalysis of polysaccharide chains?

<p>To cut the polysaccharide chain, which is its substrate (A)</p> Signup and view all the answers

What is the function of coenzymes in enzyme-catalyzed reactions?

<p>To assist in enzyme-catalyzed reactions such as hydrolysis (C)</p> Signup and view all the answers

What is the result of the conditions created in the microenvironment of the lysozyme active site?

<p>An impressive increase in hydrolysis rate (B)</p> Signup and view all the answers

What type of molecule is attached to rhodopsin in the eye?

<p>A lightsensitive molecule called retinal (C)</p> Signup and view all the answers

What is the central atom of the heme ring?

<p>Iron (C)</p> Signup and view all the answers

What is the purpose of a multienzyme complex in cells?

<p>To increase the rate of cell metabolism (D)</p> Signup and view all the answers

What is the effect of conformational coupling between two separate binding sites?

<p>Reciprocal effect on each other's binding (D)</p> Signup and view all the answers

What do GAP and GEF regulate in GTP-binding proteins?

<p>The type of nucleotide bound (D)</p> Signup and view all the answers

What is the function of covalent modification patterns in cells?

<p>To provide specific meanings to the cell (B)</p> Signup and view all the answers

What is a characteristic of motor proteins?

<p>Random back-and-forth wandering (C)</p> Signup and view all the answers

What is a common feature of heme groups in hemoglobin?

<p>Tightly bound to each of the four polypeptide chains (C)</p> Signup and view all the answers

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