Protein Structure and Function
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Questions and Answers

What percentage of protein does the adult body contain?

  • 10-15%
  • 20-25%
  • 12-18% (correct)
  • 5-10%
  • Which of the following represents the correct definition of protein?

  • Simple sugars used for energy
  • Macromolecules containing carbon, hydrogen, and nitrogen (correct)
  • Minerals required for body functions
  • Small molecules made up of nucleotides
  • Which type of amino acid is characterized by having a negatively charged side chain?

  • Neutral polar amino acid
  • Neutral non-polar amino acid
  • Acidic amino acid (correct)
  • Basic amino acid
  • What is the name of the bond that joins amino acids together?

    <p>Peptide bond (B)</p> Signup and view all the answers

    How are amino acids classified based on their interaction with water?

    <p>By their charge and hydrophilicity (C)</p> Signup and view all the answers

    Which chain length represents a tripeptide?

    <p>3 amino acids (C)</p> Signup and view all the answers

    What is the primary structure of a protein?

    <p>The linear sequence of amino acids (A)</p> Signup and view all the answers

    What is the role of the liver in relation to amino acids?

    <p>It synthesizes some non-essential amino acids. (C)</p> Signup and view all the answers

    Flashcards

    Protein

    Large macromolecules made of amino acids, containing carbon, hydrogen, oxygen, nitrogen, and sometimes sulfur.

    Functions of Protein

    Proteins are essential for building body structures, enzymes, hormones, and immune functions.

    Amino Acids

    The building blocks of proteins, with 20 common types; 10 are essential and must be acquired from diet.

    Peptide Bond

    A covalent bond that links amino acids together to form proteins.

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    Levels of Protein Structure

    Proteins have four structural levels: primary, secondary, tertiary, and quaternary organization.

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    Dipeptide and Tripeptide

    Dipeptide: chain of 2 amino acids; Tripeptide: chain of 3 amino acids.

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    Classification of Amino Acids

    Amino acids can be classified as non-polar, polar, acidic, or basic based on their interaction with water.

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    Primary Structure of Protein

    The linear sequence of amino acids in a polypeptide chain connected by peptide bonds.

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    Study Notes

    Protein Structure

    • Proteins are large macromolecules composed of carbon, hydrogen, oxygen, and nitrogen.
    • Some proteins also contain sulfur.
    • Adult bodies are approximately 12-18% protein.
    • Proteins have four levels of structural organization.

    Protein Functions

    • Proteins perform a variety of functions, including structural support, regulation (e.g., hormones), contraction (e.g., muscles), immunological defense (e.g., antibodies), transportation (e.g., hemoglobin), and catalysis (e.g., enzymes).
    • Proteins form the framework of tissues like bone, skin, and hair.
    • Proteins like enzymes speed up chemical reactions in biological systems.
    • Hormones like insulin regulate blood-sugar levels.
    • Hemoglobin carries oxygen in the blood.

    Amino Acids

    • The building blocks of proteins are amino acids.
    • There are 20 common amino acids.
    • The liver synthesizes 10 of these amino acids; the other 10 are essential and must be obtained from the diet.
    • Amino acids are composed of an amino group (NH2), a carboxyl group (COOH), a hydrogen atom (H), and a variable side chain (R group).

    Amino Acid Classification

    • Amino acids are classified according to their interaction with water:
      • Neutral non-polar amino acids are hydrophobic and interact poorly with water.
      • Neutral polar amino acids are hydrophilic and interact favorably with water.
      • Acidic amino acids are negatively charged.
      • Basic amino acids are positively charged.

    Protein Structure Levels

    • Primary Structure: A linear sequence of amino acids linked by peptide bonds.
    • Secondary Structure: Regular substructures formed within a polypeptide chain; examples are alpha helices and beta sheets, stabilized by hydrogen bonds.
    • Tertiary Structure: Three-dimensional structure of a single polypeptide chain, resulting from folding of the secondary structure; folding is determined by interactions between amino acid side chains.
    • Quaternary Structure: Arrangement of multiple polypeptide chains (subunits) to form a functional protein. Hemoglobin (a protein responsible for oxygen transport in red blood cells) is an example.

    Protein Metabolism

    • Metabolism encompasses all chemical processes in the body.
    • Catabolism breaks down complex molecules into simpler components.
    • Anabolism builds complex molecules from simpler ones.
    • Digestion catabolizes proteins into amino acids, which are then used to build new proteins for bodily function.

    Chain of Amino Acids

    • The basic building blocks of proteins are amino acids.
      • A chain of 2 amino acids is called a dipeptide.
      • A chain of 3 amino acids is called a tripeptide.
      • A chain of 4-9 amino acids is called a peptide.
      • A chain of 10 or more amino acids is called a polypeptide.

    Summary

    • Proteins are essential macromolecules with diverse roles in life processes.
    • Amino acids are the fundamental building blocks of proteins.
    • The hierarchical structure of proteins (primary, secondary, tertiary, quaternary) impacts their form and function.
    • Protein structure and function are tightly intertwined.

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    Description

    This quiz covers the essential concepts of protein structure and function, including the four levels of structural organization and the various roles proteins play in the body. You will also learn about amino acids, the building blocks of proteins, and their essential nature in the diet.

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