Quiz 17
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Questions and Answers

Which of the following proteins promotes lamellipodia and filopodia formation?

  • Rho, Rac, Cdc42 (correct)
  • Fascin and Villin
  • Filamin
  • All of the above

Microtubules are inherently unstable unless they____.

  • bind to cap proteins (correct)
  • are stabilized by minus end attachments.
  • are bound to kinesin.
  • are assembled in the nucleus.

Most microtubules are made up of 13 ___________ that are linear chains of ____and _____ dimers.

  • tubulin centrioles; gamma tubulin
  • actin rings; alpha and beta tubulin
  • protofilaments; alpha and beta tubulin (correct)
  • microfilaments; gamma and beta tubulin

Shown below is a diagram of a centrosome and associated microtubules. What is the identity of the structure in red, indicated by the black dashed arrow?

<p>gamma-tubulin ring complex (C)</p> Signup and view all the answers

At the leading edge of a cell, ARP proteins help form new branches on actin filaments to push the leading edge forward using the force of the polymerization, as shown in the figure below. What type of structure is being formed?

<p>lamellipodium (A)</p> Signup and view all the answers

Which of the following motor proteins has one head domain, moves along actin toward the plus end, and is found in all cell types?

<p>myosin-I (B)</p> Signup and view all the answers

Which end of a microtubule assembles more rapidly?

<p>(+) end. (A)</p> Signup and view all the answers

The absence of ADP and ATP causes______.

<p>tighly attaches the myosin head to the actin filament. (D)</p> Signup and view all the answers

Calcium is released from the___upon t-tubule activation.

<p>sarcoplasmic reticulum (C)</p> Signup and view all the answers

Which of the following images shows microtubules? A=left, B=middle, C=right

<p>B (B)</p> Signup and view all the answers

Study Notes

Microtubules and Cell Motility

  • ARP proteins promote lamellipodia and filopodia formation at the leading edge of a cell.
  • Microtubules are inherently unstable unless they are capped at their plus end.
  • Most microtubules are made up of 13 protofilaments that are linear chains of α-tubulin and β-tubulin dimers.
  • The structure in red, indicated by the black dashed arrow in the diagram, is a centriole.
  • ARP proteins help form new branches on actin filaments to push the leading edge forward using the force of polymerization.
  • The type of structure being formed at the leading edge is lamellipodia or filopodia.
  • The motor protein that has one head domain, moves along actin toward the plus end, and is found in all cell types is Myosin I.
  • The plus end of a microtubule assembles more rapidly.
  • The absence of ADP and ATP causes microtubule depolymerization.
  • Calcium is released from the sarcoplasmic reticulum upon t-tubule activation.
  • Image C (right) shows microtubules.

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