6 Questions
Where in the cell were labeled proteins found minutes after injection of radioactive amino acids?
Small ribonucleoprotein particles
Who identified ribosomes as the site of protein synthesis from amino acids?
Paul Zamecnik
What was found to activate amino acids for protein synthesis in liver cells?
ATP
What type of RNA was discovered and characterized by Robert Holley?
Transfer RNA (tRNA)
Which enzymes catalyze the process of amino acids becoming attached to tRNA to form aminoacyl-tRNAs?
Aminoacyl-tRNA synthetases
Who, along with Paul Zamecnik, found that amino acids were 'activated' for protein synthesis using ATP and liver cell cytosolic fraction?
Mahlon Hoagland
Learn about the early experiments by Paul Zamecnik and his colleagues in the 1950s that helped advance our knowledge of protein biosynthesis, involving the injection of radioactive amino acids into rats and subcellular fractionation of the liver homogenate.
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