18 Questions
What adverse effect may be caused by α1-blockers in relation to ejaculation?
Retrograde ejaculation
How can the exaggerated orthostatic hypotensive response to these drugs be minimized?
Adjusting the first dose to one-third or one-fourth of the normal dose
Which of the following is NOT an adverse effect of α1-blockers?
Increased energy levels
How do β-blockers differ from α1-blockers in terms of postural hypotension induction?
Only β-blockers induce postural hypotension
Which condition may be caused by α1-blockers during intraoperative eye surgery?
Floppy iris syndrome
In hypertensive patients, what improvement may be observed in lipid profiles and glucose metabolism due to these drugs?
Improvement in lipid profiles and glucose metabolism
Which adverse effect is associated with blocking β2 receptors in the lungs?
Bronchoconstriction
What is a contraindication for nonselective β-blockers like propranolol?
Asthma
How does propranolol lower blood pressure in hypertension?
By decreasing cardiac output
What is the primary mechanism through which propranolol reduces chest pain in angina?
Decreasing cardiac output
Why is careful monitoring of blood glucose essential when propranolol is given to a diabetic patient receiving insulin?
Due to risk of hypoglycemia
What action do nonselective β-blockers like propranolol have on the cardiovascular system related to isoproterenol?
Block the actions of isoproterenol
Why is propranolol contraindicated in patients with COPD or asthma?
It exacerbates bronchoconstriction in these patients.
What is the risk associated with abruptly stopping treatment with β-blockers?
Worsening of angina symptoms
How do β-blockers affect glycogenolysis and glucagon secretion?
Decrease glycogenolysis and glucagon secretion
What is one of the major roles of β receptors in mobilizing energy molecules?
Mobilizing free fatty acids for energy production
How do nonselective β-blockers affect lipid profiles in patients?
Increase LDL levels and triglycerides while reducing HDL levels
Why do β-blockers blunt the symptoms of hypoglycemia such as tremor and tachycardia?
By preventing the counterregulatory effects of catecholamines during hypoglycemia
Test your knowledge on contraindications and side effects associated with propranolol, including its use in patients with COPD or asthma, risk of cardiac arrhythmias, and potential sexual impairment. Learn about the importance of tapering off β-blocker treatment gradually.
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