Progressive Cell Injury Responses

What is the response characterized by cell size reduction and a decrease in functional capacity?

Which type of cell injury is characterized by severe cell swelling and breakdown of organelles?

What is the 'point of no return' in cell injury indicative of?

In what process do cytoplasmic vesicles engulf cytoplasm and organelles to recycle cellular components?

Which type of injury reflects a chronic response to persistent stimuli affecting organelles or cytoskeleton?

Progressive Cell Injury Types and Responses

Adaptation: Responses include atrophy, hypertrophy, hyperplasia, and metaplasia.
Active Cell Injury: An immediate response of the entire cell.
Reversible Cell Injury: Characterized by loss of ATP, cellular swelling, detachment of ribosomes, and autophagy of lysosomes.
Irreversible Cell Injury: A "point of no return" when severe, marked by vacuolization of mitochondria and calcium influx to the cell.
Necrosis: A common type of cell death with severe swelling and organelle breakdown.
Apoptosis (Programmed Cell Death): Cellular self-destruction to eliminate unwanted cells.
Autophagy: Eating of self, where cytoplasmic vesicles engulf cytoplasm and organelles, like a cellular recycling process.
Chronic Cell Injury: A persistent stimulus may only affect specific organelles or the cytoskeleton (example: phagocytosis of bacteria).
Accumulations or Infiltrations: Examples include water, pigments, lipids, glycogen, and proteins.
Pathologic Calcification: Dystrophic and metastatic calcification are types.

Explore the various types of cell injuries and their responses, including adaptation, reversible and irreversible injury, and forms of cell death such as necrosis and apoptosis. This quiz will help deepen your understanding of how cells respond to stress and damage.