Podcast
Questions and Answers
What is the response characterized by cell size reduction and a decrease in functional capacity?
What is the response characterized by cell size reduction and a decrease in functional capacity?
- Hyperplasia
- Hypertrophy
- Metaplasia
- Atrophy (correct)
Which type of cell injury is characterized by severe cell swelling and breakdown of organelles?
Which type of cell injury is characterized by severe cell swelling and breakdown of organelles?
- Metaplasia
- Necrosis (correct)
- Apoptosis
- Adaptation
What is the 'point of no return' in cell injury indicative of?
What is the 'point of no return' in cell injury indicative of?
- Detachment of ribosomes
- Loss of ATP
- Activation of autophagy
- Severe mitochondrial vacuolization (correct)
In what process do cytoplasmic vesicles engulf cytoplasm and organelles to recycle cellular components?
In what process do cytoplasmic vesicles engulf cytoplasm and organelles to recycle cellular components?
Which type of injury reflects a chronic response to persistent stimuli affecting organelles or cytoskeleton?
Which type of injury reflects a chronic response to persistent stimuli affecting organelles or cytoskeleton?
Flashcards
Cellular Adaptation
Cellular Adaptation
A cell's ability to adjust its structure and function in response to stress without dying.
Reversible Cell Injury
Reversible Cell Injury
A type of cell injury where the cell can recover from damage and return to normal function.
Necrosis
Necrosis
A type of cell death that occurs due to severe injury and the cell cannot recover.
Apoptosis
Apoptosis
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Autophagy
Autophagy
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Study Notes
Progressive Cell Injury Types and Responses
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Adaptation: Responses include atrophy, hypertrophy, hyperplasia, and metaplasia.
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Active Cell Injury: An immediate response of the entire cell.
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Reversible Cell Injury: Characterized by loss of ATP, cellular swelling, detachment of ribosomes, and autophagy of lysosomes.
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Irreversible Cell Injury: A "point of no return" when severe, marked by vacuolization of mitochondria and calcium influx to the cell.
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Necrosis: A common type of cell death with severe swelling and organelle breakdown.
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Apoptosis (Programmed Cell Death): Cellular self-destruction to eliminate unwanted cells.
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Autophagy: Eating of self, where cytoplasmic vesicles engulf cytoplasm and organelles, like a cellular recycling process.
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Chronic Cell Injury: A persistent stimulus may only affect specific organelles or the cytoskeleton (example: phagocytosis of bacteria).
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Accumulations or Infiltrations: Examples include water, pigments, lipids, glycogen, and proteins.
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Pathologic Calcification: Dystrophic and metastatic calcification are types.
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