Professionalism and Interpersonal Skills

DNA Replication

• Replication is the process of producing two identical DNA molecules from a single DNA molecule.

Central Dogma of Molecular Biology

• The central dogma outlines the flow of genetic information from DNA to proteins:
  • DNA to DNA: Replication
  • DNA to RNA: Transcription
  • RNA to Protein: Translation

Genes and Genome

• A gene is a piece of DNA that codes for a specific protein.
• The human genome contains 35,000 to 50,000 genes.
• Genes are composed of:
  • Exons: Coding parts of the gene.
  • Introns: Non-coding parts of the gene.

Objectives of DNA Replication Lectures

• Define replication and its process.
• Describe the steps of eukaryotic and prokaryotic DNA replication, including the function of enzymes and proteins involved.
• List different types of DNA polymerase (eukaryotic and prokaryotic) and their functions.
• Define topoisomerases and list different types used clinically.