Podcast
Questions and Answers
During which stage of development are red blood cells primarily produced in the yolk sac?
During which stage of development are red blood cells primarily produced in the yolk sac?
The liver is the only organ that produces red blood cells during the middle trimester of gestation.
The liver is the only organ that produces red blood cells during the middle trimester of gestation.
False
What organ produces red blood cells exclusively during the last month of gestation and after birth?
What organ produces red blood cells exclusively during the last month of gestation and after birth?
bone marrow
From ages 0-5, red blood cells are produced in __________ bones.
From ages 0-5, red blood cells are produced in __________ bones.
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Match the age range with the red blood cell production status:
Match the age range with the red blood cell production status:
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Study Notes
RBC Production Timeline
- In early embryonic life, the yolk sac generates primitive, nucleated red blood cells.
- During the middle trimester of gestation, the liver takes the lead in RBC production, with supplementary contributions from the spleen and lymph nodes.
- In the last month of gestation and post-birth, bone marrow becomes the exclusive site for RBC production.
Age-Related Changes in RBC Production
- From birth to 5 years, all bones contribute to RBC formation.
- From ages 5 to 20, RBC production shifts to most bones, excluding proximal portions of the humeri and tibiae.
- After age 20, RBCs are mainly produced in membranous bones, including vertebrae, sternum, ribs, and ilia.
- Bone marrow productivity declines with age, leading to decreased RBC production efficiency over time.
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Description
This quiz covers the production of red blood cells (RBCs) during different stages of human development, starting from embryonic life to after birth. Explore how the sites of RBC production shift from the yolk sac to the liver, and finally to the bone marrow. Test your knowledge on the timeline and locations involved in erythropoiesis.