Probiotics and Antibiotics Interaction
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Questions and Answers

What is the purpose of normal flora in the GI tract and eyes?

  • To maintain balance and prevent colonization of pathogenic species (correct)
  • To support the growth of pathogenic bacteria
  • To develop resistance to antibiotics
  • To cause infections in the absence of antibiotics

    • How does disrupting normal flora through infection affect bacterial abundance?

  • It has no effect on bacterial abundance
  • It has a variable effect on bacterial abundance
  • It increases bacterial abundance (correct)
  • It decreases bacterial abundance

    • What is an important consideration when prescribing antibiotics?

  • The patient's previous experience with antibiotics
  • The patient's preference for antibiotic type
  • The patient's allergies to antibiotics
  • The patient's immune system status (correct)

    • Why is it crucial to understand the organism causing the infection before prescribing antibiotics?

    <p>Antibiotics may not work for certain organisms</p> Signup and view all the answers

    How does oral use of antibiotics potentially impact antibiotic resistance?

    <p>It increases antibiotic resistance</p> Signup and view all the answers

    Under what circumstances can normal microbial flora become pathogenic?

    <p>During immunosuppression</p> Signup and view all the answers

    What role does normal microbial flora play in preventing the colonization of pathogenic species?

    <p>It competes with pathogenic species for resources</p> Signup and view all the answers

    What is the minimum concentration of drug which can kill 99.99% of the organism population?

    <p>Minimum bactericidal concentration (MBC)</p> Signup and view all the answers

    Which type of antibiotic kills bacteria?

    <p>Bactericidal</p> Signup and view all the answers

    What does the term 'bacteriostatic' refer to?

    <p>Working with the immune system to inhibit bacteria growth</p> Signup and view all the answers

    In what situation can high concentrations of some bacteriostatic agents be bactericidal?

    <p>When used in high doses</p> Signup and view all the answers

    What is the minimum concentration of drug which can inhibit the growth of the microorganism?

    <p>Minimum inhibitory concentration (MIC)</p> Signup and view all the answers

    When is it necessary for a bacteriostatic antibiotic to work with the immune system?

    <p>To remove the microorganisms from the body</p> Signup and view all the answers

    Why might there not always be a precise distinction between static and cidal antibiotics?

    <p>Because high concentrations of some bacteriostatic agents can be bactericidal</p> Signup and view all the answers

    What is the recommended timing for taking probiotics with antibiotics?

    <p>At least 2 hours before or after the antibiotic dose</p> Signup and view all the answers

    What is a common side effect of probiotics?

    <p>Flatulence</p> Signup and view all the answers

    Why should probiotics be used cautiously with patients taking immunosuppressants?

    <p>They may lead to infections in immunosuppressed patients</p> Signup and view all the answers

    What effect can oral antibiotics have on the normal flora in the gastrointestinal tract?

    <p>They alter the balance of normal flora</p> Signup and view all the answers

    What should be looked for when choosing a probiotic product?

    <p>High Colony Forming Units (CFU) and strain diversity</p> Signup and view all the answers

    Why is it important not to take probiotics and antibiotics at the same time?

    <p>To allow each to act effectively</p> Signup and view all the answers

    What is a potential consequence of taking probiotics with antibiotics without spacing them adequately?

    <p>Reduced effectiveness of antibiotics</p> Signup and view all the answers

    What is one of the potential reasons for the inconsistency in study findings over time regarding oral contraceptive (OC) failure with oral antibiotics?

    <p>Decreased enterohepatic circulation</p> Signup and view all the answers

    How does antibiotic-induced diarrhea impact the effectiveness of oral contraceptives?

    <p>It increases liver p450 enzyme induction</p> Signup and view all the answers

    What is a potential consequence of increased liver p450 enzyme induction?

    <p>Increased drug absorption</p> Signup and view all the answers

    Why are some studies supporting the use of nutritional probiotics considered less controlled?

    <p>The studies have inconsistencies over time</p> Signup and view all the answers

    What is a suggested benefit of taking nutritional probiotics?

    <p>Maintenance of natural flora in the gut</p> Signup and view all the answers

    Why is it important to keep natural flora in check?

    <p>To maintain a healthy gut environment</p> Signup and view all the answers

    What is one of the potential failure rate associated with oral contraceptives (OCs)?

    <p>1-3%</p> Signup and view all the answers

    What are some of the various hypotheses regarding the interaction between oral antibiotics and oral contraceptives?

    <p>Increased drug absorption, increased liver p450 enzyme induction, decreased enterohepatic circulation</p> Signup and view all the answers

    What is a potential consequence of inconsistent study findings over time regarding oral contraceptive (OC) failure with oral antibiotics?

    <p>Decreased enterohepatic circulation</p> Signup and view all the answers

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