Principles of Pharmacy Practice: Reducing and Enlarging Formulas

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14 Questions

What is the total quantity of Glycerin required to prepare 1000 mL of the solution in Example 1?

20 g

What is the total quantity of Polyvinyl Alcohol required to prepare a dozen 30-mL containers of artificial tears in Example 3?

16.8 g

What is the percentage of Sterile Sodium Chloride Solution in the artificial tears formula in Example 3?

9%

What is the total quantity of Zinc Oxide required to make 1000 g of the ointment in Example 5?

154 g

What is the proportion of Hydrophilic Ointment in the ointment formula in Example 5?

76.9%

What method is used to calculate the quantity of each ingredient required to make 1000 g of the ointment in Example 5?

Proportional Method

What is the main objective of reducing or enlarging pharmaceutical formulas?

To adjust the quantity of the formula based on the desired or available quantities

Which of the following methods is used to reduce or enlarge formulas?

Calculating the Factor Method

What is the purpose of calculating the factor in reducing or enlarging formulas?

To calculate the new quantities of each ingredient

If the value of the factor is greater than 1, what does it represent?

A multiple of the formula to be prepared

What is the term used when the value of the factor is less than 1?

Reducing Factor (RF)

What is the formula to calculate the factor in reducing or enlarging formulas?

Quantity of desired formula / Quantity of given formula

What is the purpose of the example provided in the lecture?

To calculate the quantity of each ingredient required

What is the unit of the quantity calculated in the example?

Milliliters (mL)

Study Notes

Reducing and Enlarging Formulas

  • Reducing or enlarging pharmaceutical preparations involve changing quantities while maintaining the same ratio and concentrations.

Calculating the Factor Method

  • This method involves calculating a factor to multiply each ingredient's quantity to obtain the desired formula.
  • Factor = Quantity of desired formula / Quantity of given formula
  • If the factor is > 1, it's an Enlarging Factor (EF); if < 1, it's a Reducing Factor (RF).

Examples

  • Example 2: Calculating quantities for calamine lotion preparation using the factor method.
  • Example 3: Calculating quantities for artificial tears preparation using the factor method.

Proportional Method

  • This method involves using ratios to calculate ingredient quantities.

Examples

  • Example 5: Calculating quantities for ointment preparation using the proportional method.
  • Total number of parts (by weight) = sum of individual parts; used to calculate quantities for a desired total weight.

This quiz covers reducing and enlarging formulas in pharmaceutical preparations, a crucial skill for pharmacists. Learn how to adjust quantities based on desired or available amounts.

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