Podcast
Questions and Answers
Which type of cells mostly produce IgM (with some IgD) in the primary response?
Which type of cells mostly produce IgM (with some IgD) in the primary response?
- Memory B cells
- Germinal center B cells
- Plasma cells (correct)
- Naive B cells
What is the main isotype expressed by most memory B cells according to the text?
What is the main isotype expressed by most memory B cells according to the text?
- IgA
- IgG (correct)
- IgE
- IgM
What happens to the affinity of antibodies with repeated immunization?
What happens to the affinity of antibodies with repeated immunization?
- Decreases
- Increases (correct)
- Fluctuates
- Stays the same
Which type of B cells will outcompete the primary response due to their increased affinity?
Which type of B cells will outcompete the primary response due to their increased affinity?
What happens as the immune response progresses from secondary to tertiary responses?
What happens as the immune response progresses from secondary to tertiary responses?
What is a distinguishing feature of central memory T cells?
What is a distinguishing feature of central memory T cells?
What is a functionally unique characteristic of memory T cells compared to naive T cells?
What is a functionally unique characteristic of memory T cells compared to naive T cells?
Which cytokine can lead to increased expression of Bcl-2 in memory T cells?
Which cytokine can lead to increased expression of Bcl-2 in memory T cells?
Which type of memory T cells contribute better to first-line defenses?
Which type of memory T cells contribute better to first-line defenses?
What is the outcome of the experiment regarding CD8+ Memory T cells in MHCII deficient mice?
What is the outcome of the experiment regarding CD8+ Memory T cells in MHCII deficient mice?
What role does CD4+ T cell activation with MHCII play in CD8+ T cell longevity?
What role does CD4+ T cell activation with MHCII play in CD8+ T cell longevity?
What is the primary difference between active and passive immunization?
What is the primary difference between active and passive immunization?
What is the purpose of adjuvants in vaccines?
What is the purpose of adjuvants in vaccines?
Why do early childhood vaccinations typically start at 6 months of age?
Why do early childhood vaccinations typically start at 6 months of age?
What can happen with both passive and active immunization due to original antigenic sin?
What can happen with both passive and active immunization due to original antigenic sin?
Why do attenuated vaccines have built-in adjuvants?
Why do attenuated vaccines have built-in adjuvants?
What is the purpose of promoting some inflammation in weak antigen-stimulating situations?
What is the purpose of promoting some inflammation in weak antigen-stimulating situations?
Why is a passive immunization considered temporary?
Why is a passive immunization considered temporary?
How do vaccines induce active immunity?
How do vaccines induce active immunity?
How does herd immunity reduce the pathogen reservoir?
How does herd immunity reduce the pathogen reservoir?
