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Questions and Answers
What is the name of the outer layer of skin?
What is the name of the outer layer of skin?
Epidermis
The epidermis is made up of living cells.
The epidermis is made up of living cells.
False (B)
What substance is produced by the sebaceous glands?
What substance is produced by the sebaceous glands?
Sebum
Which of the following is NOT a primary defence against pathogens?
Which of the following is NOT a primary defence against pathogens?
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What is the name of the process that involves platelets and clotting factors?
What is the name of the process that involves platelets and clotting factors?
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Blood clotting is a specific immune response.
Blood clotting is a specific immune response.
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What does the term 'enzyme cascade' refer to?
What does the term 'enzyme cascade' refer to?
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What is the name of the protein that forms a mesh during blood clotting, trapping platelets and red blood cells?
What is the name of the protein that forms a mesh during blood clotting, trapping platelets and red blood cells?
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Serotonin is released by platelets to help blood vessels contract.
Serotonin is released by platelets to help blood vessels contract.
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What is the name of the dead cells that form a scab after a wound heals?
What is the name of the dead cells that form a scab after a wound heals?
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What is a natural biological response to foreign stimuli or tissue damage?
What is a natural biological response to foreign stimuli or tissue damage?
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Which of the following is NOT a sign of inflammation?
Which of the following is NOT a sign of inflammation?
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What type of cells release histamine during inflammation?
What type of cells release histamine during inflammation?
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Which of the following is NOT a characteristic of expulsive reflexes?
Which of the following is NOT a characteristic of expulsive reflexes?
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Coughing helps to clear the airway and prevent pathogens from entering the lungs.
Coughing helps to clear the airway and prevent pathogens from entering the lungs.
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What is the name of the reflex that is primarily used to clear the nasal passages and upper respiratory tract?
What is the name of the reflex that is primarily used to clear the nasal passages and upper respiratory tract?
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Mucus membranes form a physical barrier against pathogens.
Mucus membranes form a physical barrier against pathogens.
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What type of cells secrete mucus to trap pathogens?
What type of cells secrete mucus to trap pathogens?
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Cilia are hair-like structures that help to move mucus along the airways.
Cilia are hair-like structures that help to move mucus along the airways.
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What is the name of the passage that connects the middle ear to the back of the throat?
What is the name of the passage that connects the middle ear to the back of the throat?
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The female reproductive system is considered to be a sterile environment.
The female reproductive system is considered to be a sterile environment.
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Flashcards
Epidermis
Epidermis
The outermost layer of skin, composed of dead, hardened cells filled with keratin. Acts as a physical barrier against pathogens.
Keratin
Keratin
A fibrous protein that makes up the majority of the epidermis, providing strength and protection.
Keratinization
Keratinization
The process by which cells in the base of the epidermis divide, migrate outwards, and produce keratin, eventually becoming dead, hardened cells.
Sebum
Sebum
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Blood clotting
Blood clotting
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Platelets
Platelets
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Clotting factors
Clotting factors
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Enzyme cascade
Enzyme cascade
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Thrombin
Thrombin
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Fibrinogen
Fibrinogen
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Fibrin
Fibrin
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Scab
Scab
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Stem cells
Stem cells
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Inflammation
Inflammation
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Mast cells
Mast cells
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Histamine
Histamine
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Vasodilation
Vasodilation
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Increased capillary permeability
Increased capillary permeability
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Tissue fluid
Tissue fluid
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Lymphocytes
Lymphocytes
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Expulsive reflexes
Expulsive reflexes
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Coughing
Coughing
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Sneezing
Sneezing
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Mucous membrane
Mucous membrane
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Goblet cells
Goblet cells
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Mucus
Mucus
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Cilia
Cilia
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Trachea (windpipe)
Trachea (windpipe)
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Oesophagus
Oesophagus
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Stomach acid
Stomach acid
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Tear fluid
Tear fluid
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Ear wax
Ear wax
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Cervix
Cervix
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Study Notes
Primary Defences Against Diseases
- Pathogenic organisms must enter the host body to cause harm
- Animals have evolved primary defences to prevent pathogenic organism entry
- These defences are non-specific, preventing any pathogen entry
The Skin
- The epidermis, the outer skin layer, is composed of dead, hardened cells filled with keratin
- Keratin acts as a physical barrier against pathogens
- Keratinisation is the process where cells at the epidermis base multiply, migrate outwards, dry out and die, forming a keratinised layer of dead skin cells
- Sebum, an oily substance produced by sebaceous glands, creates an acidic layer on the skin's surface
- This acidic layer prevents the growth of harmful bacteria
- Harmless microorganisms on the skin's surface also reduce pathogen growth
Blood Clotting & Skin Repair
- Blood clots form when skin is wounded to prevent infection and excessive blood loss
- Platelets release clotting factors
- Clotting factors activate an enzyme cascade, a chain reaction of enzymes activating each other
- Thromboplastin and calcium ions convert prothrombin into thrombin
- Thrombin catalyses the conversion of fibrinogen into fibrin, forming a mesh to trap platelets and red blood cells, forming a blood clot
- Platelets also release serotonin, causing blood vessel smooth muscle to contract, reducing blood flow to the damaged area and drawing the cut edges together
- The blood clot dries to form a scab, preventing pathogen entry
- Stem cells within the epidermis form new skin cells, replacing damaged ones beneath the scab
- The scab eventually detaches when new cells are complete
Inflammation
- Inflammation is a natural biological response to tissue damage or foreign stimuli
- Indicators include swelling, redness, heat, and pain
- Mast cells detect microorganisms in tissue
- Capillary walls become more permeable to white blood cells and proteins
- White blood cells and plasma exit blood vessels into tissue, causing swelling
- Excess tissue fluid drains into the lymphatic system
- Lymphocytes in the lymphatic system come in contact with pathogens, triggering a specific immune response
Expulsive Reflexes (Coughing and Sneezing)
- Expulsive reflexes expel harmful substances like pathogens from the body
- Coughing expels air from the lungs to clear airways, combating infections like bronchitis
- Sneezing expels irritants/pathogens from the nasal passages and upper respiratory tract
Mucous Membranes
- Mucous membranes are exchange surfaces where substances like oxygen and nutrients enter the blood
- Thin membranes are less protected from pathogens
- The respiratory system, digestive system, eyes, and ears are exposed to air and food which may contain microorganisms
- Mucous membranes line these areas to protect them
- Goblet cells secrete mucus, trapping pathogens
- Ciliated cells move the mucus, removing pathogens and carrying them to the oesophagus
- Pathogens often destroyed by stomach acidity
Other Primary Defences
- Body fluids like tears and saliva contain antibodies and digestive enzymes which help protect against pathogens in eyes and digestive systems
- Ear canals are lined with wax which traps pathogens
- The female reproductive system has a mucus plug in the cervix to maintain acidic conditions, preventing pathogen entry
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Description
This quiz explores the body's primary defenses against diseases, focusing on the skin's structure and function. Learn how the skin acts as a barrier to pathogens and the role of blood clotting in protecting the body. Test your knowledge about these crucial biological defenses.