Prenatal Screening Tests Overview

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Questions and Answers

What is the primary purpose of the Double Test?

  • To estimate the risk for chromosomal abnormalities (correct)
  • To assess the mother's overall health
  • To measure the baby's heart rate
  • To provide a definitive diagnosis of chromosomal abnormalities

When is the Double Test typically performed during pregnancy?

  • 11 to 14 weeks (correct)
  • 20 to 24 weeks
  • 16 to 18 weeks
  • 6 to 9 weeks

Which substances are measured in the Double Test blood test?

  • AFP and Estriol
  • Alpha-fetoprotein and progesterone
  • Free beta-hCG and PAPP-A (correct)
  • hCG and Estriol

What does an increased nuchal translucency measurement indicate?

<p>Higher risk of chromosomal abnormalities (D)</p> Signup and view all the answers

What is the primary significance of the Triple Test during pregnancy?

<p>It helps predict the risk of neural tube defects and chromosomal abnormalities (A)</p> Signup and view all the answers

At what stage of pregnancy is the Triple Test typically performed?

<p>16 to 18 weeks (D)</p> Signup and view all the answers

Which of the following substances is NOT measured in the Triple Test?

<p>Free beta-hCG (D)</p> Signup and view all the answers

What type of tests are both the Double Test and Triple Test classified as?

<p>Screening tests (D)</p> Signup and view all the answers

If the results of the screening tests indicate a high risk, what may be recommended?

<p>Further diagnostic tests such as amniocentesis (B)</p> Signup and view all the answers

Which test assesses the risk for neural tube defects?

<p>Triple Test (D)</p> Signup and view all the answers

Flashcards

Double Test

A screening test for chromosomal abnormalities, performed between 11 and 14 weeks of pregnancy, using a blood test and ultrasound.

Blood Test (Double Test)

Measures free beta-hCG and PAPP-A in the mother's blood to identify potential chromosomal abnormalities.

Ultrasound (Double Test)

Nuchal translucency scan measures the fluid at the back of the baby's neck to help assess risk.

Triple Test

Second-trimester screening test for chromosomal abnormalities (like Down syndrome) and neural tube defects, performed between 16-18 weeks.

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Triple Test blood test

Measures AFP, hCG, and estriol in the mother's blood to assess risk.

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AFP (Alpha-fetoprotein)

Protein produced by the baby's liver, measured in the Triple Test.

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hCG (Human Chorionic Gonadotropin)

Hormone produced by the placenta, measured in both the Double and Triple Tests.

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Estriol

A type of estrogen produced by both the baby and the placenta.

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Screening Test

A test that assesses risk but does not provide a definitive diagnosis.

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Amniocentesis

A diagnostic test (not a screening test) that can confirm chromosomal abnormalities and other conditions.

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Chorionic Villus Sampling (CVS)

An early diagnostic test (not a screening test) used to assess for chromosomal abnormalities.

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Study Notes

Double Test (First-Trimester Screening)

  • Performed between 11 and 14 weeks of pregnancy
  • Involves a blood test and an ultrasound
    • Blood test measures free beta-hCG and PAPP-A
    • Ultrasound measures nuchal translucency (NT) of the fetus
  • Increased NT thickness suggests higher risk of chromosomal abnormalities
  • Assesses risk for Down syndrome (Trisomy 21) and Trisomy 18
  • Does not provide a definitive diagnosis, only estimates risk
  • High risk results may prompt further diagnostic tests (e.g., amniocentesis)

Triple Test (Second-Trimester Screening)

  • Performed between 16 and 18 weeks, but can be up to 20 weeks
  • A blood test measuring three substances in the mother's blood
    • AFP (Alpha-fetoprotein): Produced by the baby's liver
    • hCG (Human Chorionic Gonadotropin): Produced by the placenta
    • Estriol: An estrogen produced by both baby and placenta
  • Assesses risk for Down syndrome (Trisomy 21), Trisomy 18, and neural tube defects (e.g., spina bifida)
  • Does not provide a definitive diagnosis, only estimates risk
  • High risk results may prompt further diagnostic tests (e.g., amniocentesis)

General Information

  • Both tests are screening tests, not diagnostic
  • High risk results may lead to further tests like amniocentesis or CVS.

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