Prednisone (Deltasone) Flashcards

Questions and Answers

What is the generic name of Deltasone?

Corticosteroids

Anti asthmatic

Prednisone (correct)

Grapefruit juice

What is the therapeutic class of prednisone?

Anti asthmatic, corticosteroids

What is the pharmacologic class of prednisone?

Corticosteroids (systemic)

Identify the uses/indications of prednisone.

Used systemically and locally in a wide variety of chronic diseases including Inflammatory, Allergic, Hematologic, Neoplastic, Autoimmune disorders, as well as Asthma Signup and view all the answers

What is the action of prednisone?

Suppress inflammation and the normal immune response Signup and view all the answers

What are the contraindications for prednisone?

Active untreated infections, Administration of live virus vaccines Signup and view all the answers

In which conditions should prednisone be used cautiously?

Chronic treatment, Hyperthyroidism, Respiratory TB, Untreated infections, Diabetes, Renal/Hepatic impairment Signup and view all the answers

List the drug interactions of prednisone.

Increase risk of hypokalemia with thiazide and loop diuretics; Increase risk for GI effects with NSAIDs; St.John's Wort may decrease concentration; Grapefruit juice may increase serum levels of budesonide Signup and view all the answers

What assessments should be done for a patient on prednisone?

Assess for signs of adrenal insufficiency, monitor intake and output ratios, daily weights, BP, serum electrolytes, glucose, and signs of infection. Signup and view all the answers

What is the proper implementation of prednisone?

Capsules should be swallowed whole, do not crush, break or chew; Avoid consumption of grapefruit juice Signup and view all the answers

What are the desired outcomes when using prednisone?

Decrease signs/symptoms with minimal systemic side effects, suppression of inflammatory and immune responses, improve symptoms of Crohn's Disease, management of adrenal insufficiency. Signup and view all the answers

Match the side effects/adverse reactions of prednisone:

Peptic Ulceration = Adverse reaction Thromboembolism = Adverse reaction Euphoria = Side effect Depression = Side effect Headache = Side effect Nausea = Side effect Vomiting = Side effect Anorexia = Side effect Acne = Side effect Decreased wound healing = Adverse reaction Adrenal suppression = Adverse reaction Cushingoid appearance = Adverse reaction Osteoporosis = Adverse reaction Muscle wasting = Adverse reaction Ecchymoses = Adverse reaction Fragility = Adverse reaction Signup and view all the answers

Study Notes

Prednisone Overview

Generic name: prednisone
Brand name: Deltasone
Therapeutic class: Anti-asthmatic, corticosteroids
Pharmacologic class: Corticosteroids (systemic)

Uses and Actions

Indicated for a variety of chronic diseases including:
- Inflammatory disorders
- Allergic reactions
- Hematologic conditions
- Neoplastic diseases
- Autoimmune disorders
- Asthma management
Function:
- Suppresses inflammation and immune responses
- Prevents and decreases inflammatory processes

Pharmacokinetics and Contraindications

Pharmacokinetics: Unknown
Contraindications include:
- Active untreated infections
- Administration of live virus vaccines

Caution and Interactions

Use with caution in patients with:
- Chronic therapy needs
- Hyperthyroidism
- Respiratory tuberculosis
- Untreated infections
- Diabetes
- Renal or hepatic impairment
Drug interactions:
- Increased risk of hypokalemia with thiazide and loop diuretics
- Higher GI effects risk with NSAIDs
- St. John's Wort may reduce drug concentration; Cat's claw and echinacea may stimulate immune response
- Grapefruit juice may raise serum levels of certain medications

Assessments and Administration

Regular assessments for adrenal insufficiency should be conducted
Monitor:
- Patient's intake/output ratios and daily weight
- Signs of peripheral edema and respiratory distress
- Blood pressure and serum electrolytes
- Glucose levels and bone mineral density
- Possible infections
Administration notes:
- Capsules must be swallowed whole
- Grapefruit juice should be avoided during use

Desired Outcomes

Goals of therapy include:
- Reduction of symptoms with minimal systemic side effects
- Effective suppression of inflammatory and immune responses in various conditions
- Improvement in symptoms associated with Crohn's Disease
- Management of adrenal insufficiency

Side Effects and Adverse Reactions

Potential side effects include:
- Peptic ulceration
- Risk of thromboembolism
- Euphoria or depression
- Headache, nausea, vomiting, and anorexia
- Acne and decreased wound healing
- Adrenal suppression and cushingoid appearance
- Osteoporosis, muscle wasting, and ecchymoses (bruising)
- Increased fragility in patients

Description

Test your knowledge on Prednisone, also known as Deltasone, with these flashcards. Learn about its generic name, therapeutic class, pharmacologic class, and various uses. This quiz is ideal for anyone studying pharmacology or related health fields.