Post-Traumatic Syringomyelia Pathophysiology

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5 Questions

What was the atypical clinical presentation of the patient with post-traumatic syringomyelia?

Loss of pain, temperature, and fine touch in the left upper limb

Why was the absence of pyramidal signs in the patient explained?

Sparing of the corticospinal tracts

What surgical technique did the patient undergo initially for alleviating dysesthetic pain?

Laminectomy with direct drainage of the syrinx

What is one key aspect to consider in diagnosing syringomyelia based on the text?

Absence of pyramidal signs

Why was meningitis ruled out as the cause of syringomyelia in this case?

Absence of significant adhesive arachnoiditis in the MRI

Study Notes

Pathophysiology of Post-Traumatic Syringomyelia

  • The exact pathophysiology of post-traumatic syringomyelia is not fully understood
  • Factors contributing to syrinx formation include: mechanical compression of the spinal cord, inflammation, hematoma, release of intracellular lysosomal enzymes, ischemia, and obstruction of arterial and venous supply

Clinical Presentation of Syringomyelia

  • Classic presentation: cape-like bilateral distribution of pain and temperature loss in the shoulders, arms, and hands due to destruction of spinothalamic tracts
  • The dorso-lateral column of the spinal cord is often spared, leaving fine touch, vibration, and proprioception intact
  • Atypical presentations can occur due to variability in syrinx location within the spinal cord

Case Report: Unusual Presentation of Syringomyelia

  • Patient presented with loss of pain, temperature, and fine touch in the left upper limb, with severe dysesthetic pain in the neck, shoulder, and upper back
  • Unusual non-dissociated type of sensory loss explained by expansion of syrinx affecting posterior columns of the spinal cord or compression of dorso-lateral region
  • Absence of pyramidal signs due to sparing of corticospinal tracts

Surgical Management of Post-Traumatic Syringomyelia

  • Laminectomy with direct drainage of the syrinx can provide temporary relief from dysesthetic pain
  • Shunting procedures (syringo-peritoneal, syringo-pleural, or syringo-subarachnoid) may be considered, but their superiority is controversial
  • Surgery can enhance quality of life and reduce healthcare costs, even with modest improvement or temporary halting of neurological deterioration

Explore the factors believed to precede the formation of syrinx within the spinal cord in post-traumatic syringomyelia. Learn about mechanical compression, inflammation, hematoma, lysosomal enzymes, ischemia, and vascular supply obstruction contributing to syrinx expansion.

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