18 Questions
What is the proposed mechanism for malignant hyperthermia?
Exposure to halogenated anesthetic agents leads to increased muscle contraction due to release of Ca2+ from skeletal muscle sarcoplasmic reticulum, depletion of ATP, increased O2 consumption, CO2 production, and heat, resulting in membrane failure and leakage of K+, creatinine kinase, and myoglobin.
Which of the following anesthetic agents has NOT been found to cause malignant hyperthermia?
Nitrous oxide
Which of the following muscle relaxants has been identified as a trigger for malignant hyperthermia?
Succinylcholine
Which of the following is NOT a risk factor for developing malignant hyperthermia?
Exposure to benzodiazepines
Which of the following is the most appropriate initial treatment for a patient experiencing malignant hyperthermia?
Discontinue the triggering anesthetic agent and administer dantrolene
Which of the following statements about the definition of malignant hyperthermia is INCORRECT?
Malignant hyperthermia is not an emergency situation and does not require immediate treatment.
Which of the following is the recommended treatment for outpatient pneumonia?
Amoxicillin plus macrolide
What is the primary symptom of a urinary tract infection?
Dysuria (painful urination)
Which of the following is NOT a symptom of a wound infection?
Hypotension (low blood pressure)
What is the recommended diagnostic test for deep vein thrombosis (DVT)?
Venous duplex ultrasound
Which of the following is NOT a potential cause of post-operative fever after 7 days?
Pneumonia
What is the recommended diagnostic test for pulmonary embolism (PE)?
Any of the above
Which of the following is NOT a clinical feature of malignant hyperthermia?
Hypotension
What is the initial recommended dose of dantrolene for treating malignant hyperthermia?
2.5 mg/kg
Which of the following is the most common cause of postoperative fever on days 1-2?
Pneumonia/atelectasis
Which of the following is a symptom of atelectasis?
All of the above
What is the normal range for body temperature in postoperative patients?
36.1°C - 37.2°C
Which of the following is the recommended treatment for malignant hyperthermia?
All of the above
Learn about the evaluation, diagnosis, and treatment of febrile patients in the post-operative period, as well as malignant hyperthermia - a pharmacogenetic disorder that can result in a hypermetabolic response to certain triggers.
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