Post-Operative Fever and Malignant Hyperthermia
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Questions and Answers

What is the proposed mechanism for malignant hyperthermia?

  • Exposure to halogenated anesthetic agents leads to increased muscle relaxation due to increased release of Ca2+ from skeletal muscle sarcoplasmic reticulum, increased ATP production, decreased O2 consumption, CO2 production, and heat, resulting in membrane failure and leakage of K+, creatinine kinase, and myoglobin.
  • Exposure to halogenated anesthetic agents leads to decreased muscle contraction due to release of Ca2+ from skeletal muscle sarcoplasmic reticulum, depletion of ATP, decreased O2 consumption, CO2 production, and heat, resulting in membrane failure and leakage of K+, creatinine kinase, and myoglobin.
  • Exposure to halogenated anesthetic agents leads to decreased muscle relaxation due to decreased release of Ca2+ from skeletal muscle sarcoplasmic reticulum, decreased ATP production, increased O2 consumption, CO2 production, and heat, resulting in membrane failure and leakage of K+, creatinine kinase, and myoglobin.
  • Exposure to halogenated anesthetic agents leads to increased muscle contraction due to release of Ca2+ from skeletal muscle sarcoplasmic reticulum, depletion of ATP, increased O2 consumption, CO2 production, and heat, resulting in membrane failure and leakage of K+, creatinine kinase, and myoglobin. (correct)

    • Which of the following anesthetic agents has NOT been found to cause malignant hyperthermia?

  • Halothane
  • Enflurane
  • Desflurane
  • Nitrous oxide (correct)

    • Which of the following muscle relaxants has been identified as a trigger for malignant hyperthermia?

  • Succinylcholine (correct)
  • Nondepolarizing muscle relaxants
  • Ketamine
  • Propofol

    • Which of the following is NOT a risk factor for developing malignant hyperthermia?

    <p>Exposure to benzodiazepines (C)</p> Signup and view all the answers

    Which of the following is the most appropriate initial treatment for a patient experiencing malignant hyperthermia?

    <p>Discontinue the triggering anesthetic agent and administer dantrolene (D)</p> Signup and view all the answers

    Which of the following statements about the definition of malignant hyperthermia is INCORRECT?

    <p>Malignant hyperthermia is not an emergency situation and does not require immediate treatment. (D)</p> Signup and view all the answers

    Which of the following is the recommended treatment for outpatient pneumonia?

    <p>Amoxicillin plus macrolide (A)</p> Signup and view all the answers

    What is the primary symptom of a urinary tract infection?

    <p>Dysuria (painful urination) (A)</p> Signup and view all the answers

    Which of the following is NOT a symptom of a wound infection?

    <p>Hypotension (low blood pressure) (D)</p> Signup and view all the answers

    What is the recommended diagnostic test for deep vein thrombosis (DVT)?

    <p>Venous duplex ultrasound (D)</p> Signup and view all the answers

    Which of the following is NOT a potential cause of post-operative fever after 7 days?

    <p>Pneumonia (C)</p> Signup and view all the answers

    What is the recommended diagnostic test for pulmonary embolism (PE)?

    <p>Any of the above (D)</p> Signup and view all the answers

    Which of the following is NOT a clinical feature of malignant hyperthermia?

    <p>Hypotension (A)</p> Signup and view all the answers

    What is the initial recommended dose of dantrolene for treating malignant hyperthermia?

    <p>2.5 mg/kg (D)</p> Signup and view all the answers

    Which of the following is the most common cause of postoperative fever on days 1-2?

    <p>Pneumonia/atelectasis (C)</p> Signup and view all the answers

    Which of the following is a symptom of atelectasis?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the normal range for body temperature in postoperative patients?

    <p>36.1°C - 37.2°C (B)</p> Signup and view all the answers

    Which of the following is the recommended treatment for malignant hyperthermia?

    <p>All of the above (D)</p> Signup and view all the answers

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