Post-kala-azar dermal leishmaniasis

High fever, marked splenomegaly, hepatomegaly, and severe cachexia

Intermittent fever, weakness, loss of energy, and gradual spleen enlargement

Massive hepatosplenomegaly, profound pancytopenia, jaundice, edema, ascites, frequent bleeding episodes, secondary bacterial infections

<p>Younger age at the time of infection and underlying malnutrition</p> Signup and view all the answers

<p>Demonstration of amastigotes in tissue specimens by direct microscopy or isolation of the organism by culture</p> Signup and view all the answers

<p>Pentavalent antimonies, Amphotericin B, Pentamidine isethionate, Paromomycin, Recombinant human interferon-γ, Miltefosine</p> Signup and view all the answers

<p>Fatigue, arthralgia, elevated liver enzymes, hematological manifestations, cardiac toxicity</p> Signup and view all the answers

<p>Avoiding exposure to sandflies by using insect repellent and mosquito netting, controlling infectious reservoir, treating patients</p> Signup and view all the answers

<p>Hypopigmented, erythematous, or nodular lesions commonly involving the face (around chin and nose) and trunk.</p> Signup and view all the answers

<p>It is thought to be caused by the treatment and complete eradication of the parasite in the circulation, leading to its escape to the tissue and causing the skin reaction.</p> Signup and view all the answers

<ol> <li>Malaria 2. Military tuberculosis 3. Brucellosis 4. Typhoid fever 5. Amebic liver abscess 6. Infectious mononucleosis 7. Lymphoma and leukemia 8. Schistosomiasis.</li> </ol> Signup and view all the answers

<p>I. CBC: pancytopenia (severe anemia, leucopenia, &amp; thrombocytopenia) II. LFT: Elevated liver enzymes. III. Serology: Indirect fluorescence assay or ELISA with recombinant antigen (K39).</p> Signup and view all the answers