Polymyositis Diagnosis
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Questions and Answers

What is the percentage of patients with normal serum creatine kinase levels in dermatomyositis?

  • 30%
  • 40%
  • 20%
  • 10% (correct)

What is the characteristic feature of muscle biopsy in dermatomyositis?

  • Fibrosis is the primary feature
  • Perifascicular atrophy is present in all patients
  • Perifascicular atrophy is present in only 50% of patients (correct)
  • Muscle inflammation is absent

What is the specific antibody associated with amyopathic dermatomyositis?

  • Anti-Mi2
  • Anti-MDA5 (correct)
  • Anti-NXP2
  • Anti-TIF1

What is the most common inflammatory cell found in muscle biopsy in dermatomyositis?

<p>Macrophages (A)</p> Signup and view all the answers

What is the prognosis of dermatomyositis in the absence of malignancy?

<p>Favorable (B)</p> Signup and view all the answers

What is the primary goal of exercise therapy in dermatomyositis?

<p>To improve muscle function (D)</p> Signup and view all the answers

What is the primary mechanism by which dermatomyositis is mediated?

<p>Complement activation (B)</p> Signup and view all the answers

What is the characteristic rash of dermatomyositis that is pathognomonic for the disease?

<p>Gottron sign (A)</p> Signup and view all the answers

What is the primary pattern of muscle weakness in dermatomyositis?

<p>Symmetric proximal weakness (A)</p> Signup and view all the answers

What is the role of creatine kinase in the diagnosis of dermatomyositis?

<p>It is a sensitive laboratory marker for muscle destruction (D)</p> Signup and view all the answers

What is the main characteristic of Dermatomyositis?

<p>An immune-mediated disease that attacks the muscles in the body (A)</p> Signup and view all the answers

Which of the following is a characteristic feature of Dermatomyositis?

<p>Symmetric proximal weakness without cutaneous lesion (C)</p> Signup and view all the answers

What is the underlying pathogenesis of dermatomyositis?

<p>Autoimmune disease (D)</p> Signup and view all the answers

What is the characteristic skin rash that occurs over the extensor surfaces of joints in dermatomyositis?

<p>Gottron papules (A)</p> Signup and view all the answers

What is the significance of increased CK levels in Dermatomyositis?

<p>It is an indication of muscle damage and inflammation (B)</p> Signup and view all the answers

What is the percentage of cancer risk associated with Dermatomyositis?

<p>15% within the first 2-3 years (A)</p> Signup and view all the answers

What is the significance of Gottron papules in Dermatomyositis?

<p>It is a characteristic skin lesion of Dermatomyositis (C)</p> Signup and view all the answers

What is the main reason for screening for cancer in patients with Dermatomyositis?

<p>Because Dermatomyositis can be paraneoplastic (B)</p> Signup and view all the answers

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