Podcast
Questions and Answers
What can result from an abnormal initiation of tooth development?
What can result from an abnormal initiation of tooth development?
What is the role of the inner enamel epithelium during histodifferentiation?
What is the role of the inner enamel epithelium during histodifferentiation?
What disturbance occurs during proliferation that can affect tooth development?
What disturbance occurs during proliferation that can affect tooth development?
What is osteodentin?
What is osteodentin?
Signup and view all the answers
What is the purpose of morphodifferentiation in tooth development?
What is the purpose of morphodifferentiation in tooth development?
Signup and view all the answers
How does vitamin A deficiency affect tooth development?
How does vitamin A deficiency affect tooth development?
Signup and view all the answers
Which teeth are most commonly associated with supernumerary teeth?
Which teeth are most commonly associated with supernumerary teeth?
Signup and view all the answers
When does reciprocal induction occur during tooth development?
When does reciprocal induction occur during tooth development?
Signup and view all the answers
What is amelogenesis?
What is amelogenesis?
Signup and view all the answers
During which stage of tooth development does amelogenesis begin?
During which stage of tooth development does amelogenesis begin?
Signup and view all the answers
Which type of proteins primarily make up the organic matrix of enamel?
Which type of proteins primarily make up the organic matrix of enamel?
Signup and view all the answers
What is the primary role of amelogenins in enamel formation?
What is the primary role of amelogenins in enamel formation?
Signup and view all the answers
What occurs during the secretory phase of enamel formation?
What occurs during the secretory phase of enamel formation?
Signup and view all the answers
What is the function of matrix vesicles during the maturative phase?
What is the function of matrix vesicles during the maturative phase?
Signup and view all the answers
What is the primary function of the stellate reticulum in the enamel organ?
What is the primary function of the stellate reticulum in the enamel organ?
Signup and view all the answers
Which structure forms a knob-like enlargement toward the dental papilla?
Which structure forms a knob-like enlargement toward the dental papilla?
Signup and view all the answers
Which of the following proteins is classified under nonamelogenins?
Which of the following proteins is classified under nonamelogenins?
Signup and view all the answers
During which stage does the enamel organ take on a bell shape?
During which stage does the enamel organ take on a bell shape?
Signup and view all the answers
How is enamel thickness primarily regulated during enamel formation?
How is enamel thickness primarily regulated during enamel formation?
Signup and view all the answers
What is the role of stratum intermedium in the enamel organ?
What is the role of stratum intermedium in the enamel organ?
Signup and view all the answers
What happens to the stellate reticulum before the formation of enamel?
What happens to the stellate reticulum before the formation of enamel?
Signup and view all the answers
What type of cells make up the inner enamel epithelium before the formation of enamel?
What type of cells make up the inner enamel epithelium before the formation of enamel?
Signup and view all the answers
What is the appearance of the cells in the center of the stellate reticulum?
What is the appearance of the cells in the center of the stellate reticulum?
Signup and view all the answers
What defines the dental sac during the cap stage?
What defines the dental sac during the cap stage?
Signup and view all the answers
What is the primary source of the posterior one-third of the tongue?
What is the primary source of the posterior one-third of the tongue?
Signup and view all the answers
What is the role of enamel on the teeth?
What is the role of enamel on the teeth?
Signup and view all the answers
At approximately what stage of embryo development does enamel formation begin?
At approximately what stage of embryo development does enamel formation begin?
Signup and view all the answers
What is the maximum thickness of enamel found over molars?
What is the maximum thickness of enamel found over molars?
Signup and view all the answers
Which component of the tongue is indicated by the terminal sulcus?
Which component of the tongue is indicated by the terminal sulcus?
Signup and view all the answers
What primarily determines the color and translucency of enamel?
What primarily determines the color and translucency of enamel?
Signup and view all the answers
Which characteristic best describes enamel?
Which characteristic best describes enamel?
Signup and view all the answers
What is the primary component of enamel that contributes to its hardness?
What is the primary component of enamel that contributes to its hardness?
Signup and view all the answers
What disturbance can occur during morphodifferentiation affecting the crown of a tooth?
What disturbance can occur during morphodifferentiation affecting the crown of a tooth?
Signup and view all the answers
What does apposition primarily involve in tooth development?
What does apposition primarily involve in tooth development?
Signup and view all the answers
What term describes disturbances involving the formation of the enamel matrix?
What term describes disturbances involving the formation of the enamel matrix?
Signup and view all the answers
Which of the following structures derives from the fronto-nasal process during face development?
Which of the following structures derives from the fronto-nasal process during face development?
Signup and view all the answers
What do hypocalcification and hypomineralization indicate in tooth development?
What do hypocalcification and hypomineralization indicate in tooth development?
Signup and view all the answers
From which embryonic structure do the paired mandibular prominences develop?
From which embryonic structure do the paired mandibular prominences develop?
Signup and view all the answers
What is the primary focus of disturbances occurring during the morphodifferentiation process?
What is the primary focus of disturbances occurring during the morphodifferentiation process?
Signup and view all the answers
At what embryonic week does the development of face structures mainly occur?
At what embryonic week does the development of face structures mainly occur?
Signup and view all the answers
Where is cementum thinnest?
Where is cementum thinnest?
Signup and view all the answers
What characterizes acellular afibrillar cementum?
What characterizes acellular afibrillar cementum?
Signup and view all the answers
Which type of cementum is primarily found in the apical third of roots?
Which type of cementum is primarily found in the apical third of roots?
Signup and view all the answers
What is the role of incremental lines of Salter in cementum?
What is the role of incremental lines of Salter in cementum?
Signup and view all the answers
What happens at the cementoenamel junction in 60% of teeth?
What happens at the cementoenamel junction in 60% of teeth?
Signup and view all the answers
Which type of cementum is formed by cementoblasts and lacks extrinsic collagen fibers?
Which type of cementum is formed by cementoblasts and lacks extrinsic collagen fibers?
Signup and view all the answers
Why is cementum resistant to resorption compared to bone?
Why is cementum resistant to resorption compared to bone?
Signup and view all the answers
What is a characteristic of acellular extrinsic fiber cementum?
What is a characteristic of acellular extrinsic fiber cementum?
Signup and view all the answers
Flashcards
Stellate Reticulum
Stellate Reticulum
Star-shaped, branching network of cells found in the enamel organ's center; acts as a shock absorber protecting enamel-forming cells.
Primary Enamel Knot
Primary Enamel Knot
Knob-like structure on the inner surface of the enamel organ; a key area directing enamel formation.
Enamel Cord
Enamel Cord
Vertical extension of the primary enamel knot, positioned centrally in the enamel organ.
Ameloblasts
Ameloblasts
Signup and view all the flashcards
Stratum Intermedium
Stratum Intermedium
Signup and view all the flashcards
Inner Enamel Epithelium
Inner Enamel Epithelium
Signup and view all the flashcards
Outer Enamel Epithelium
Outer Enamel Epithelium
Signup and view all the flashcards
Glycosaminoglycans
Glycosaminoglycans
Signup and view all the flashcards
Supernumerary Teeth
Supernumerary Teeth
Signup and view all the flashcards
Mesiodens
Mesiodens
Signup and view all the flashcards
Proliferation (in tooth development)
Proliferation (in tooth development)
Signup and view all the flashcards
Histodifferentiation
Histodifferentiation
Signup and view all the flashcards
Odontoblasts
Odontoblasts
Signup and view all the flashcards
Reciprocal Induction
Reciprocal Induction
Signup and view all the flashcards
Osteodentin
Osteodentin
Signup and view all the flashcards
Morphodifferentiation
Morphodifferentiation
Signup and view all the flashcards
Supernumerary Cusp
Supernumerary Cusp
Signup and view all the flashcards
Peg-shaped Tooth
Peg-shaped Tooth
Signup and view all the flashcards
Dilaceration
Dilaceration
Signup and view all the flashcards
Apposition
Apposition
Signup and view all the flashcards
Hypoplasia
Hypoplasia
Signup and view all the flashcards
Hypocalcification
Hypocalcification
Signup and view all the flashcards
Hypomineralization
Hypomineralization
Signup and view all the flashcards
Posterior 1/3 of tongue
Posterior 1/3 of tongue
Signup and view all the flashcards
Terminal Sulcus
Terminal Sulcus
Signup and view all the flashcards
Enamel: Introduction
Enamel: Introduction
Signup and view all the flashcards
Enamel: Physical Properties
Enamel: Physical Properties
Signup and view all the flashcards
Enamel: Thickness
Enamel: Thickness
Signup and view all the flashcards
Enamel: Color & Translucency
Enamel: Color & Translucency
Signup and view all the flashcards
Enamel: Hardness
Enamel: Hardness
Signup and view all the flashcards
Enamel: Composition
Enamel: Composition
Signup and view all the flashcards
Hydroxyapatite Fluoride
Hydroxyapatite Fluoride
Signup and view all the flashcards
Calcium Hydroxyapatite
Calcium Hydroxyapatite
Signup and view all the flashcards
Amelogenesis
Amelogenesis
Signup and view all the flashcards
What are the two main phases of Amelogenesis?
What are the two main phases of Amelogenesis?
Signup and view all the flashcards
Enamel Proteins
Enamel Proteins
Signup and view all the flashcards
Amelogenins
Amelogenins
Signup and view all the flashcards
Non-Amelogenins
Non-Amelogenins
Signup and view all the flashcards
Cementum Thickness
Cementum Thickness
Signup and view all the flashcards
Cementocytes
Cementocytes
Signup and view all the flashcards
Acellular Afibrillar Cementum
Acellular Afibrillar Cementum
Signup and view all the flashcards
Acellular Extrinsic Fiber Cementum
Acellular Extrinsic Fiber Cementum
Signup and view all the flashcards
Cellular Mixed Stratified Cementum
Cellular Mixed Stratified Cementum
Signup and view all the flashcards
Cellular Intrinsic Fiber Cementum
Cellular Intrinsic Fiber Cementum
Signup and view all the flashcards
Incremental Lines of Salter
Incremental Lines of Salter
Signup and view all the flashcards
Cementodentinal Junction
Cementodentinal Junction
Signup and view all the flashcards
Study Notes
Germ Layer Formation
- Germ layers form from the morula, a ball of cells, in mammals after fertilization.
- The major portion of the egg cell mass forms extraembryonic membranes and structures like the placenta.
- The inner cell mass, embryoblast, separates into two layers: the epiblast and hypoblast.
- Only the epiblast forms the embryo.
- The hypoblast and other cells form supporting tissues like the placenta.
- The process of formation of the three germ layers is called gastrulation.
- Gastrulation involves the formation of a primitive streak and primitive node.
- Epiblast cells divide and migrate through the primitive streak, replacing hypoblast cells and forming endoderm.
- Cells between the epiblast and endoderm form the mesoderm.
- Cells remaining in the epiblast form the ectoderm, completing the three germ layers.
- The notochord is a solid cord formed by prenotochordal cells between the ectoderm and endoderm that reaches the prochordal plate.
- The notochord forms the basis for the vertebral column in later development, persisting partially as the nucleus pulposus of the vertebral disks.
Neural Tube Formation
- In the midline, the ectoderm over the notochord thickens to form the neural plate.
- The neural plate furrows to form the neural groove.
- Neural folds on either side of the groove elevate, fuse, and form the neural tube.
- Neural crest cells develop from the neural folds and migrate to other locations in the body, contributing to a variety of tissues like odontoblasts, melanocytes, and ganglia.
Pharyngeal Arches
- Pharyngeal arches develop progressively, contributing to the face and neck.
- Each arch contains skeletal elements, arteries, muscles, and nerves.
- The first arch (mandibular arch) gives rise to muscles of mastication, mylohyoid, anterior belly of digastric, tensor veli palatini and tensor tympani.
- It also gives rise to Meckel's cartilage(malleus, incus, anterior ligament of malleus, sphenomandibular ligament.)
- The mandibular nerve supplies muscles of mastication; chorda tympani and maxillary artery are also part of the first arch.
- The second arch (hyoid arch) gives rise to muscles of facial expression, posterior belly of digastric, stylohyoid, stapedius.
- It also gives rise to Reichert's cartilage(stapes, stylohyoid ligament, lesser cornu and upper half of body of hyoid bone, styloid process).
- The facial nerve and stapedial artery are part of the second arch.
- Derivatives of the third arch are the stylopharyngeus muscle and the greater horn and lower part of the hyoid bone.
- The glossopharyngeal nerve supplies the third arch.
- The fourth and sixth arches give rise to parts of the larynx, including the cricothyroid, levator palatine, constrictor of pharynx, intrinsic muscle of larynx, laryngeal cartilages.
- The superior laryngeal (4th) and recurrent laryngeal nerve(6th) innervate those structures.
- Ectodermal clefts and endodermal pouches from between the arches develop into various structures including the auditory tube, palatine tonsils, and parathyroid glands.
Development of Teeth
- Teeth form from ectoderm and ectomesenchyme.
- At 37 days, a thickened band of epithelium appears in the developing jaws and is shaped like a horseshoe.
- The primary epithelial band gives rise to other subdivisions including the dental lamina.
- The initiation of tooth development starts with the formation of localized thickenings or placodes in the primary epithelial bands.
- A series of 10 local thickenings occur in the dental lamina, and each placode forms one deciduous tooth.
- Tooth development proceeds through the bud, cap, and bell stages.
- The bud stage is characterized by the formation of a tooth bud as the epithelial cells proliferate into the ectomesenchyme of the jaw.
- The supporting ectomesenchymal cells densely pack around the epithelial bud.
- This results in condensation of ectomesenchyme.
- The cap stage involves the formation of dental papilla.
- The enamel organ and the dental papilla form the tooth germ.
- The bell stage sees the enamel organ taking a bell shape.
- Cells that will form the hard tissues of the crown (ameloblasts(forming enamel) and odontoblasts (forming dentin)) acquire histodifferentiation at this stage.
- The enamel organ has four layers during the bell stage: inner enamel epithelium, stratum intermedium, the stellate reticulum, and outer enamel epithelium.
- The cells in the center of the concavity of the enamel organ form a structure called the primary enamel knot. The enamel knot extends vertically across the center of the enamel organ -- called the enamel cord.
- Cells of the dental papilla appear crowded at the cap stage.
- The dental papilla and dental sac become more vascular at the cap stage.
- The dental sac is more condensed and fibrous in the cap stage.
- Mineralization starts during the advanced bell stage, and root formation commences.
- Mineralisation involves the differentiation of the peripheral cells of the dental papilla into odontoblasts and the secretion of organic matrix.
- The line separating the odontoblasts and the inner enamel epithelium forms the dentinoenamel junction.
- Enamel formation happens in two phases: secretory and maturative.
- The secretory phase involves protein secretion by ameloblasts (forming enamel); the maturative phase involves reabsorption of proteins and water, and mineral secretion.
- The epithelial root sheath forms the epithelial diaphragm prior to root formation.
- The proliferation of cells of the epithelial diaphragm is accompanied by the proliferation of connective tissue adjacent to the diaphragm.
- Tooth development can begin during the advanced bell stage, characterized by the start of mineralization and root formation and ends with the final shape of the crown and also involves root formation.
- The epithelial diaphragm divides into a network of epithelial strands and the surrounding connective tissue proliferates.
- Additional structures like the periodontal ligament and alveolar bone form.
- The most common teeth missing, or incomplete, are the upper lateral incisors, third molars, and lower second premolars.
Development of Face and Palate
- The face is derived from the fronto-nasal process, and first pharyngeal arch of each side.
- The first pharyngeal arch divides into the maxillary and mandibular process.
- The fronto-nasal process forms the forehead and bridge of the nose.
- The paired maxillary prominences form the upper cheek, upper lip, and maxilla, including most of the secondary palate.
- The paired mandibular prominences form the area of the chin and lower lip.
- The lateral nasal processes form the alae of the nose and
- The fusion of medial nasal processes forms the intermaxillary segment(philtrum of lip, premaxillary portion of maxilla with the upper four incisors, and the associated gums).
- The palate starts to develop at the end of the 5th week, which finishes by the 12th week with the primary palate forming in the beginning of the 6th week by the intermaxillary segment as median palatine process.
- The secondary palate forms from the internal aspects of the maxillary prominences as lateral palatine processes.
- Lateral palatine processes grow medially and fuse, merging to form the hard palate and fuse with the posterior part of the primary palate and nasal septum.
- The fusion of the lateral palatine processes with the nasal septum begins anteriorly during the 9th week and extends posteriorly to complete by the 12th week.
Development of the Tongue
- The tongue forms from the first, second, third, and fourth pharyngeal arches.
- The anterior two-thirds of the tongue form from the fusion of the tuberculum impar and the two lateral tongue swellings.
- The posterior one-third of the tongue forms from the copula.
- The swellings from the floor of the third and fourth pharyngeal arches overgrow the second arch and fuse with the anterior two-thirds of the tongue.
- The posterior one-third of the tongue is derived from the third and fourth arches.
- The intrinsic musculature also is derived from occipital myotomes.
- The line of fusion of the anterior two-thirds and posterior one-third of the tongue is indicated by the terminal sulcus.
Enamel
- Enamel is the hard, vitreous covering of the crown of the tooth.
- Enamel is made of hydroxyapatite crystals in a highly organized structure.
- Enamel forms quickly in the advanced bell stage once crown and the first layer of dentine forms..
- Enamel is composed of two phases; a secretory phase and a maturative phase.
- Enamel is made of amelogenins and nonamelogenins.
- Enamel is usually translucent and pale yellow.
- Enamel is thickest at the cusp, thinning to a knife edge at the neck of the tooth.
Dentin
- Dentin is the primary bulk of the tooth.
- Dentin surrounds the pulp cavity.
- Dentin supports the enamel.
- Dentin is composed of 70% inorganic matter, 20% organic matter, and 10% water.
- It is harder than bone and cementum but softer than enamel.
- The primary dentin, secondary dentin, and tertiary dentin are types of dentin.
- Dentin has a tubular structure with odontoblastic processes, nerves, and fluid.
- Dentin is slightly harder in the crown than near the pulp on its periphery.
- Dentin is harder in the primary teeth than the permanent teeth.
Cementum
- Cementum is a mineralized connective tissue that covers the anatomical roots of human teeth.
- It begins at the cementoenamel junction and extends to the apex of the roots.
- It serves as a medium for attachment of collagen fibers.
- It is responsible for adapting to the functional needs of the teeth.
- There are two types of cementum: acellular and cellular.
- Acellular cementum has no cells within it, while cellular cementum does.
- Acellular cementum is found in the coronal third of the roots.
- Cellular cementum is in the apical third.
- Cementum is highly resistant to resorption and is less hard than dentin.
- It is a light yellow color and has less luster compared to enamel. It is semi-permeable to various substances.
- It consists of 45-50% inorganic material, and 50-55% organic material. It has high fluoride content because of this.
- The uncalcified matrix is called cementoid. This is highly organized vs. random.
- The embedded portions of the fibers are called Sharpey's fibers. These fibers attach the tooth to surrounding bone.
- The cementodentinal junction is predominantly smooth in permanent teeth and scalloped in deciduous teeth.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.