PMED-DENT-PHARM Lecture II: Pathology Team Quiz
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Questions and Answers

Which cells predominate in the inflammatory infiltrate during the first 6-24 hours of acute inflammation?

  • Monocytes
  • Neutrophils (correct)
  • Eosinophils
  • Lymphocytes
  • Which type of cells predominantly replace neutrophils 24-48 hours after acute inflammation begins?

  • Monocytes (correct)
  • Neutrophils
  • Lymphocytes
  • Eosinophils
  • What is the main role of leukocytes in acute inflammation?

  • Removal of dead tissue from the injury site
  • Production of substances that initiate the inflammatory reaction
  • Amplification of phagocytosis for enhanced tissue repair
  • Migration towards the injury site to combat microbes (correct)
  • What is the main function of opsonins in phagocytosis by leukocytes?

    <p>Coating the target for phagocytosis</p> Signup and view all the answers

    What is the role of chemotaxis in the process of leukocyte recruitment?

    <p>Migration of leukocytes towards the injury site</p> Signup and view all the answers

    Which type of infections typically lead to a predominance of eosinophils in the inflammatory infiltrate?

    <p>Parasitic infections</p> Signup and view all the answers

    Which of the following is not a preformed cell-derived mediator involved in acute inflammation?

    <p>Prostaglandins</p> Signup and view all the answers

    Which of the following is a plasma-derived mediator that induces cellular and vascular changes in acute inflammation?

    <p>Bradykinin</p> Signup and view all the answers

    Which of the following is not a mechanism of leukocyte-induced tissue injury?

    <p>Cellular proliferation</p> Signup and view all the answers

    Which of the following is a newly synthesized cell-derived mediator that is involved in acute inflammation?

    <p>Prostaglandins</p> Signup and view all the answers

    Which of the following is a complement system-derived mediator that is involved in acute inflammation?

    <p>C5a</p> Signup and view all the answers

    Which receptors are responsible for the tumbling down of white blood cells on the endothelial cells during inflammation?

    <p>Selectins on the WBCs and endothelium.</p> Signup and view all the answers

    How do leukocytes accumulate at the periphery of the vessels during inflammation?

    <p>Because of Selectins on the WBCs and endothelium.</p> Signup and view all the answers

    Which of the following is not a reactive oxygen species involved in acute inflammation?

    <p>Nitric oxide</p> Signup and view all the answers

    What is the role of Integrins during leukocyte recruitment in inflammation?

    <p>Mediating firm adhesion of WBCs to endothelial cells.</p> Signup and view all the answers

    What is the process by which leukocytes migrate through vessel walls during inflammation?

    <p>Diapedesis.</p> Signup and view all the answers

    What causes the shape change in white blood cells as they adhere to the surface of the endothelium during inflammation?

    <p>Integrin attachment.</p> Signup and view all the answers

    Which proteins are expressed on the cell surface in response to chemical mediators of inflammation during leukocyte recruitment?

    <p>Ligands.</p> Signup and view all the answers

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