Podcast
Questions and Answers
The Freundlich-Ostwald equation is used to calculate the dissolution pressure.
The Freundlich-Ostwald equation is used to calculate the dissolution pressure.
False
Amoxicillin is an example of a poorly soluble drug with a dissolution time greater than GI transit time.
Amoxicillin is an example of a poorly soluble drug with a dissolution time greater than GI transit time.
False
Lyophilization is used to improve the re-dispersibility of solid dosage forms.
Lyophilization is used to improve the re-dispersibility of solid dosage forms.
False
Nanoparticles are used for targeted delivery with a longer time frame.
Nanoparticles are used for targeted delivery with a longer time frame.
Signup and view all the answers
Lipid-based mRNA delivery systems are a recent example of nanodelivery for vaccination.
Lipid-based mRNA delivery systems are a recent example of nanodelivery for vaccination.
Signup and view all the answers
Ciprofloxacin is an example of a poorly soluble drug with a dissolution time greater than GI transit time.
Ciprofloxacin is an example of a poorly soluble drug with a dissolution time greater than GI transit time.
Signup and view all the answers
Albumin-PTX-complex binds to SPLARC, which is overexpressed in many tumors.
Albumin-PTX-complex binds to SPLARC, which is overexpressed in many tumors.
Signup and view all the answers
Abraxane has a higher Cmax than Taxol.
Abraxane has a higher Cmax than Taxol.
Signup and view all the answers
Abraxane and Taxol have the same AUC.
Abraxane and Taxol have the same AUC.
Signup and view all the answers
The typically applied dose for Abraxane is 260 mg/m², which is better tolerated by patients.
The typically applied dose for Abraxane is 260 mg/m², which is better tolerated by patients.
Signup and view all the answers
One of the methods used to produce nanoparticles is high-pressure homogenization.
One of the methods used to produce nanoparticles is high-pressure homogenization.
Signup and view all the answers
The problems to be addressed in nanoparticle production are low drug solubility and fast dissolution.
The problems to be addressed in nanoparticle production are low drug solubility and fast dissolution.
Signup and view all the answers
PLGA nanoparticles and alginate have good solubility and permeability for drug delivery.
PLGA nanoparticles and alginate have good solubility and permeability for drug delivery.
Signup and view all the answers
Drug delivery techniques primarily focus on improving the aesthetic appearance of pharmaceuticals.
Drug delivery techniques primarily focus on improving the aesthetic appearance of pharmaceuticals.
Signup and view all the answers
Nanomedicine is a field that combines nanotechnology with medicine to develop targeted and personalized treatments.
Nanomedicine is a field that combines nanotechnology with medicine to develop targeted and personalized treatments.
Signup and view all the answers
The article by Zhang et al. in ACS Nano in 2012 has the DOI number 175, 713.
The article by Zhang et al. in ACS Nano in 2012 has the DOI number 175, 713.
Signup and view all the answers
The circulation time of cGNPs in blood is primarily determined by membrane properties.
The circulation time of cGNPs in blood is primarily determined by membrane properties.
Signup and view all the answers
Nano, in the context of nanomedicine, means a factor of 10 to the power of -12.
Nano, in the context of nanomedicine, means a factor of 10 to the power of -12.
Signup and view all the answers
Nanomedicine is primarily used for cosmetic applications in medicine.
Nanomedicine is primarily used for cosmetic applications in medicine.
Signup and view all the answers
The force spectroscopy results indicate a Fmax baseline of 0 adhesion piezo extension.
The force spectroscopy results indicate a Fmax baseline of 0 adhesion piezo extension.
Signup and view all the answers
Regulatory aspects are crucial in nanomedicine to maintain quality, safety, and efficacy.
Regulatory aspects are crucial in nanomedicine to maintain quality, safety, and efficacy.
Signup and view all the answers
The preparation of gelatin solution involves the use of crosslinking for defined times.
The preparation of gelatin solution involves the use of crosslinking for defined times.
Signup and view all the answers
Young's modulus increases linearly with crosslinking time, with a correlation coefficient r² = 0.98692.
Young's modulus increases linearly with crosslinking time, with a correlation coefficient r² = 0.98692.
Signup and view all the answers
Loading a drug into the matrix impacts the Young's modulus if the drug is crosslinked.
Loading a drug into the matrix impacts the Young's modulus if the drug is crosslinked.
Signup and view all the answers
Nanomedicine is defined as the application of 'nano' particles in medicine.
Nanomedicine is defined as the application of 'nano' particles in medicine.
Signup and view all the answers
According to the EU cosmetics guideline, a nanomaterial is insoluble or biologically persistent.
According to the EU cosmetics guideline, a nanomaterial is insoluble or biologically persistent.
Signup and view all the answers
The EU (EG) Nr 1223/2009 guideline defines a particle as any piece of matter without defined physical boundaries.
The EU (EG) Nr 1223/2009 guideline defines a particle as any piece of matter without defined physical boundaries.
Signup and view all the answers
An agglomerate is a strongly bound or fused particle, according to EU (2011) Commission Recommendation.
An agglomerate is a strongly bound or fused particle, according to EU (2011) Commission Recommendation.
Signup and view all the answers
The Commission Recommendation of 18 October 2011 defines a nanomaterial as containing particles between 1-100 nm.
The Commission Recommendation of 18 October 2011 defines a nanomaterial as containing particles between 1-100 nm.
Signup and view all the answers
The document mentions the application of 'nano' in areas other than medicine.
The document mentions the application of 'nano' in areas other than medicine.
Signup and view all the answers
