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Questions and Answers
Which platelet disorder is characterized by a lighter staining peripheral zone and maintains platelet's discoid shape?
In which stage of hemostasis does the platelet plug occur?
What is the range for severe thrombocytopenia?
Which condition is characterized by autoantibodies attacking megakaryocytes and platelets?
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Which type of Immune Thrombocytopenia is exclusively found in children?
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What is the primary etiology of Thrombotic Thrombocytopenic Purpura (TTP)?
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Which condition is characterized by microthrombi in affected organs and is different from Hemolytic Uremic syndrome?
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Which infection is associated with the pathologic process of RBC fragmentation in Thrombotic Thrombocytopenic Purpura (TTP)?
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Which platelet disorder is characterized by a lighter staining peripheral zone and maintains platelet's discoid shape?
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In which stage of hemostasis does the platelet plug occur?
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Which condition is characterized by microthrombi in affected organs and is different from Hemolytic Uremic syndrome?
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Which type of Immune Thrombocytopenia is exclusively found in children?
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Which condition is characterized by autoantibodies attacking megakaryocytes and platelets?
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What is the primary etiology of Thrombotic Thrombocytopenic Purpura (TTP)?
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Which platelet disorder is associated with weaker vessel walls due to perivascular amyloidosis?
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Which type of Immune Thrombocytopenia is common in adult women?
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Which type of Thrombocytopenia presents within the first 2 days after exposure to heparin?
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Which infection is associated with the pathologic process of RBC fragmentation in Thrombotic Thrombocytopenic Purpura (TTP)?
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At what platelet count does surgical bleeding typically occur?
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Which type of Immune Thrombocytopenia is characterized by reduced platelet count and megakaryocytes hyperplasia in bone marrow?
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Study Notes
Platelet Disorders
- Grey platelet syndrome is characterized by a lighter staining peripheral zone and maintains platelet's discoid shape.
Hemostasis
- Platelet plug occurs in the primary hemostasis stage.
Thrombocytopenia
- Severe thrombocytopenia is characterized by a platelet count of < 20,000/μL.
- Autoimmune thrombocytopenia is characterized by autoantibodies attacking megakaryocytes and platelets.
Immune Thrombocytopenia
- Acute Immune Thrombocytopenia is exclusively found in children.
- Chronic Immune Thrombocytopenia is common in adult women.
Thrombotic Thrombocytopenic Purpura (TTP)
- Primary etiology of TTP is abnormal processing of von Willebrand factor.
- Characterized by microthrombi in affected organs and is different from Hemolytic Uremic syndrome.
- Associated with Escherichia coli (E. coli) infection, which leads to RBC fragmentation.
Other Conditions
- Amyloid thrombocytopenia is associated with weaker vessel walls due to perivascular amyloidosis.
- Heparin-induced thrombocytopenia (HIT) presents within the first 2 days after exposure to heparin.
- Surgical bleeding typically occurs at a platelet count of < 50,000/μL.
- Idiopathic thrombocytopenic purpura (ITP) is characterized by reduced platelet count and megakaryocytes hyperplasia in bone marrow.
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Description
Test your knowledge of platelet disorders and bleeding disorders with this quiz. Explore the ultrastructures of platelets, including granulomere types and the maintenance of discoid shape. Learn about the primary and secondary stages of hemostasis, as well as the defects associated with primary and secondary hemostasis in bleeding disorders.
