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Questions and Answers
The total ______ protein level ranges from 6-7 gm/dl.
The total ______ protein level ranges from 6-7 gm/dl.
plasma
Plasma proteins are divided into two categories, ______ and Globulin.
Plasma proteins are divided into two categories, ______ and Globulin.
Albumin
After the age of 40, ______ gradually declines with an increase in globulins.
After the age of 40, ______ gradually declines with an increase in globulins.
albumin
The different plasma protein bands are semi-quantitated using a ______.
The different plasma protein bands are semi-quantitated using a ______.
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The ______ constitutes over half of the total protein.
The ______ constitutes over half of the total protein.
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Study Notes
Plasma Composition
- Plasma is the non-cellular portion of blood.
- Total plasma protein level ranges from 6-7 gm/dl.
Types of Plasma Proteins
- There are two main categories of plasma proteins: albumin and globulin.
Albumin
- Albumin is not precipitated by half-saturated ammonium sulfate.
- Albumin constitutes over half of the total protein.
- Albumin level ranges from 3.5-5.5 gm/dl.
- Albumin is a simple protein and a single entity.
Globulin
- Globulin is precipitated by half-saturated ammonium sulfate.
- Globulin level ranges from 2-3 gm/dl.
- Globulin is a complex protein with many components.
- Subglobulins (α1, α2, β, and γ-globulins) are detected as bands on electrophoresis.
Age-Related Changes
- After the age of 40, albumin levels gradually decline, and globulin levels increase.
Electrophoresis
- Electrophoresis is used to separate and identify plasma proteins.
- The electrophoretic pattern is shown in Fig. 1a.
- Different plasma protein bands are semi-quantitated using a densitometer (Fig. 1b).
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Description
Learn about the types and functions of plasma proteins, including albumin and globulin, and their roles in blood chemistry. Understand the classification, structure, and normal levels of these proteins.