Plasma Proteins: Structure, Function, and Classification
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Questions and Answers

The total ______ protein level ranges from 6-7 gm/dl.

plasma

Plasma proteins are divided into two categories, ______ and Globulin.

Albumin

After the age of 40, ______ gradually declines with an increase in globulins.

albumin

The different plasma protein bands are semi-quantitated using a ______.

<p>densitometer</p> Signup and view all the answers

The ______ constitutes over half of the total protein.

<p>albumin</p> Signup and view all the answers

Study Notes

Plasma Composition

  • Plasma is the non-cellular portion of blood.
  • Total plasma protein level ranges from 6-7 gm/dl.

Types of Plasma Proteins

  • There are two main categories of plasma proteins: albumin and globulin.

Albumin

  • Albumin is not precipitated by half-saturated ammonium sulfate.
  • Albumin constitutes over half of the total protein.
  • Albumin level ranges from 3.5-5.5 gm/dl.
  • Albumin is a simple protein and a single entity.

Globulin

  • Globulin is precipitated by half-saturated ammonium sulfate.
  • Globulin level ranges from 2-3 gm/dl.
  • Globulin is a complex protein with many components.
  • Subglobulins (α1, α2, β, and γ-globulins) are detected as bands on electrophoresis.
  • After the age of 40, albumin levels gradually decline, and globulin levels increase.

Electrophoresis

  • Electrophoresis is used to separate and identify plasma proteins.
  • The electrophoretic pattern is shown in Fig. 1a.
  • Different plasma protein bands are semi-quantitated using a densitometer (Fig. 1b).

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Description

Learn about the types and functions of plasma proteins, including albumin and globulin, and their roles in blood chemistry. Understand the classification, structure, and normal levels of these proteins.

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