Plasma Proteins and Their Functions

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Questions and Answers

Which plasma protein is responsible for the majority of the plasma colloidal osmotic pressure?

  • Immunoglobulins
  • Fibrinogen
  • Globulins
  • Albumin (correct)

Where are globulins primarily synthesized in the body?

  • Liver, spleen, bone marrow, and lymph glands (correct)
  • Only in the liver
  • Spleen and lungs
  • Bone marrow and lymph glands

What is the approximate range of plasma colloidal osmotic pressure?

  • 15-20 mmHg
  • 10-15 mmHg
  • 25-30 mmHg (correct)
  • 30-35 mmHg

Which function do plasma proteins primarily perform to assist in the immune response?

<p>Defense function against pathogens (D)</p> Signup and view all the answers

Which plasma protein is crucial for the process of clot formation?

<p>Fibrinogen (A)</p> Signup and view all the answers

Flashcards

Plasma proteins

Proteins found in plasma, crucial for various bodily functions.

Albumin

A plasma protein, primarily made by the liver, maintaining water balance.

Globulins

Plasma proteins involved in immunity and transporting substances.

Fibrinogen

A plasma protein crucial for blood clotting.

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Colloidal osmotic pressure

The pressure exerted by plasma proteins (mostly Albumin) to maintain fluid balance.

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Plasma Protein's role in Defence

Antibodies (primarily gamma-globulins) protect the body against pathogens.

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Plasma protein's role in Clotting

Fibrinogen is essential in blood clot formation.

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Plasma's role in Viscosity

Plasma proteins, especially fibrinogen, contribute to blood thickness.

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Plasma protein's role as Carriers

Plasma proteins transport various substances (hormones, ions, etc.).

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Liver's role in plasma protein synthesis

The liver is the primary site for albumin and fibrinogen production.

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Study Notes

Plasma Composition

  • 100 cc of plasma contains 7-8 gm of plasma proteins
  • Albumin: 4.5 gm
  • Globulins: 2.7 gm
  • Fibrinogen: 0.4 gm

Plasma Protein Synthesis

  • Albumin and fibrinogen are produced by the liver
  • Globulins are produced in the liver, spleen, bone marrow, and lymph glands

Plasma Protein Functions

  • Maintenance of Colloidal Osmotic Pressure:
    • Achieved primarily by albumin
    • Approximately 25-30 mmHg
    • Important for water exchange between blood and tissues, regulating blood volume
  • Defense Function:
    • Antibodies (primarily gamma-globulins) play a crucial role in fighting viruses and bacteria, protecting the body
  • Clot Formation:
    • Fibrinogen is essential for blood clot formation
  • Viscosity:
    • Plasma proteins, especially fibrinogen, contribute to blood viscosity, which is vital for maintaining arterial blood pressure
  • Carriers:
    • Plasma proteins transport hormones (e.g., thyroid, gonadal hormones), metal ions, fatty acids, and drugs.

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