W1-Plasma Membrane Structure and Functions

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Questions and Answers

Which of the following is a characteristic of the fluid mosaic model of the cell membrane structure?

  • The membrane is impermeable to water
  • The membrane is composed only of lipids and proteins
  • The membrane is a rigid, static structure
  • The membrane is dynamic and includes lipids, proteins, and carbohydrates (correct)

What role do ion channels play in cystic fibrosis?

  • They regulate cell size
  • They facilitate energy production
  • They contribute to dehydrated mucus leading to chronic lung infections (correct)
  • They are involved in passive transport

Which type of transport involves movement of substances against their concentration gradient?

  • Facilitated diffusion
  • $CO_2$ diffusion
  • $Na^+/K^+$ pump (correct)
  • $O_2$ diffusion

What is the significance of membranes and associated proteins in medicine?

<p>They are targets for many drugs (B)</p>
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What are the main functions of proteins on the plasma membrane?

<p>Cell-cell recognition, signal transduction, transport, enzymatic activity, and attachment (B)</p>
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What is the process that involves cell response induction by hormones or neurotransmitters?

<p>Signal transduction (D)</p>
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Which mechanism involves movement from high to low concentration towards equilibrium?

<p>Passive transport (B)</p>
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What is the process of water diffusion across a membrane to balance solute concentrations?

<p>Osmosis (D)</p>
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What is the energy source required for active transport?

<p>$ATP$ (Adenosine Triphosphate) (A)</p>
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Which components are included in the composition of the plasma membrane?

<p>Membrane lipids, proteins, and carbohydrates (B)</p>
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What is the thickness of the plasma membrane?

<p>7.5-10 nm (A)</p>
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Which of the following influences the fluidity of the membrane?

<p>Fatty acid composition, saturation, and cholesterol content (A)</p>
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What are the exclusive locations of carbohydrates in the plasma membrane?

<p>Extracellular side (C)</p>
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What is a main function of the Plasma Membrane?

<p>Cell recognition receptors and cell communication transport (C)</p>
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What is one of the key structural components that make up the Plasma Membrane?

<p>Phospholipids (C)</p>
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Study Notes

Biological Membranes and Plasma Membrane Structure

  • Biological membranes include lysosome, mitochondrial inner and outer, plasma membrane, Golgi, endoplasmic reticulum (ER), and nuclear envelope
  • Cells contain various membrane compartments, with most being around 1µm in size
  • Membranes are sheet-like structures consisting of lipids, proteins, and carbohydrates linked to lipids or proteins, and are non-covalent assemblies
  • The plasma membrane is 7.5-10 nm thick and separates living cells from their surroundings, controlling the movement of nutrients, ions, and proteins
  • Learning objectives include understanding the diversity and common features of biological membranes and the key structural components of the plasma membrane
  • The plasma membrane composition includes membrane lipids, proteins, and carbohydrates, following the fluid mosaic model
  • Lipid composition includes phospholipids, sphingomyelin, glycolipids, and cholesterol
  • Membrane proteins can be integral, peripheral, or lipid-anchored, while carbohydrates are exclusively presented on the extracellular side of the plasma membrane
  • The fluid mosaic model describes individual phospholipids and proteins moving side-to-side within the layer
  • Fluidity of the membrane is influenced by fatty acid composition, saturation, and cholesterol content
  • Cholesterol modulates membrane fluidity at different temperatures and has essential roles in regulating O2 entry and serving as a primitive cellular defense against O2
  • Sterols may have evolved in eukaryotes as an adaptive response to the rise of terrestrial O2

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