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Questions and Answers
Which of the following is true about Apo-B48?
Which of the following is true about Apo-B48?
- It is synthesized in the intestine (correct)
- It is found in LDL and VLDL
- It is an activator of LCAT enzyme
- It is synthesized in the liver
What is the function of Apo-CII?
What is the function of Apo-CII?
- It is an activator of plasma lipoprotein lipase (correct)
- It is found in VLDL, HDL, chylomicrons, and chylomicron remnants
- It includes apo-AI and apo-AII
- It is synthesized in the liver
What is the range of total plasma lipids after 12 hours fasting?
What is the range of total plasma lipids after 12 hours fasting?
- 200-500 mg/dl
- 400-700 mg/dl (correct)
- 600-900 mg/dl
- 100-300 mg/dl
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Study Notes
- Plasma lipids are measured after 12 hours fasting.
- Total plasma lipids range from 400-700 mg/dl.
- Apolipoprotein-A includes apo-AI and apo-AII.
- Apo-AI in HDL is an activator of LCAT enzyme.
- Apolipoprotein-B has two types: apo-B48 for chylomicrons and apo-B100 for LDL and VLDL.
- Apo-B48 is synthesized in the intestine, and apo-B100 is synthesized in the liver.
- Apolipoprotein-C includes apo-CI, apo-CII, and apo-CIII.
- Apo-CII is transferred from HDL to chylomicrons and VLDL and is an activator of plasma lipoprotein lipase.
- Apolipoprotein E is found in VLDL, HDL, chylomicrons, and chylomicron remnants.
- Apo E accounts for 5-10% of total VLDL apolipoproteins in normal subjects.
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