Plant-Based Vaccines and Biotechnology
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Plant-Based Vaccines and Biotechnology

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Questions and Answers

What is one benefit of using plants for vaccine production?

  • Plants can be grown in controlled environments only.
  • Plants can offer a greater volume of product than cell cultures. (correct)
  • Plants are self-sustaining without any outside nutrients.
  • Plants require less water than traditional methods.
  • Which of the following was not mentioned as a potential source for vaccines?

  • Cotton (correct)
  • Bananas
  • Tomatoes
  • Wheat
  • What kind of infection does the vaccine produced in tomatoes and bananas target?

  • Tuberculosis
  • Influenza
  • HIV
  • Hepatitis B (correct)
  • What term describes the approach of using plants to produce pharmaceuticals?

    <p>Molecular farming</p> Signup and view all the answers

    What is a challenge faced by the biopharmaceutical industry despite advancements?

    <p>Lack of regulatory approvals</p> Signup and view all the answers

    Which of the following diseases is being targeted with a plant-based pharmaceutical developed by Protalix?

    <p>Gaucher's disease</p> Signup and view all the answers

    What is an advantage of using plants over traditional cell cultures for biopharmaceuticals?

    <p>Plants can be cultivated in larger quantities.</p> Signup and view all the answers

    What type of compounds are biotechnologists extracting from plants for pharmaceutical use?

    <p>Phytochemicals</p> Signup and view all the answers

    What is the function of the mRNA molecule encoded by the transferred gene in tomato cells?

    <p>To inactivate the normal mRNA for pectinase production</p> Signup and view all the answers

    How do plant vaccines function similarly to human vaccines?

    <p>They contain altered viruses that stimulate an immune response</p> Signup and view all the answers

    What kind of viruses have plant vaccines been designed to protect against?

    <p>A range of plant viruses that affect growth and yield</p> Signup and view all the answers

    What does the Cry gene from Bacillus thuringiensis produce?

    <p>A protein that kills specific harmful insects</p> Signup and view all the answers

    How do genetically engineered plants utilize the Cry gene?

    <p>They incorporate the gene within their own DNA to resist insect damage</p> Signup and view all the answers

    What significant benefit does encoding vaccines in plant DNA provide to farmers?

    <p>It simplifies the process of delivering vaccines to crops</p> Signup and view all the answers

    What strategy is taken to protect crops from insect damage using Bacillus thuringiensis?

    <p>Natural bacterial pesticides are applied or integrated within plants</p> Signup and view all the answers

    What is one of the primary objectives of using plant vaccines in agriculture?

    <p>To stimulate the plant's natural defense mechanisms against diseases</p> Signup and view all the answers

    What is a benefit of using transgenic crops in medicine?

    <p>They can produce large amounts of commercially valuable protein.</p> Signup and view all the answers

    How do edible vaccines derived from plants work?

    <p>The plant produces a viral protein that stimulates an immune response.</p> Signup and view all the answers

    Which of the following statements about transgenic tobacco plants is true?

    <p>They can harvest human growth hormone.</p> Signup and view all the answers

    What is the role of the introduced gene in developing edible vaccines?

    <p>To enable the plant to express a protein that can trigger an immune response.</p> Signup and view all the answers

    Which organization is known for supporting the development of transgenic crops?

    <p>Bill and Melinda Gates Foundation</p> Signup and view all the answers

    What limitation does Golden Rice face in delivering vitamin A effectively?

    <p>It requires fat for beta carotene to be absorbed.</p> Signup and view all the answers

    What is one advantage of conventional breeding techniques over transgenic crops?

    <p>There is less public resistance to their use.</p> Signup and view all the answers

    The genetic modification of plants for vaccine production relies on what process?

    <p>Introducing specific genes into the plant genome.</p> Signup and view all the answers

    Study Notes

    Plant-Based Vaccines

    • The World Health Organization (WHO) called for inexpensive, non-refrigerated vaccines in the early 1990s.

    • Researchers are developing edible vaccines in plants like bananas and tomatoes.

    • Tomatoes can be engineered to produce vaccines and antibodies through their chloroplasts.

    • Biotechnologists utilize plants as "small-scale factories" to produce chemicals for human health.

    • Plant biotechnology offers a potential solution for producing complex therapeutic proteins like antibodies, hormones, and enzymes.

    • This "molecular farming" promises future applications for treating diseases like cystic fibrosis, hepatitis, and various gastrointestinal illnesses.

    • Plant-based pharmaceuticals could offer a cost-effective alternative to traditional cell culture methods for producing medications.

    • The first plant-based pharmaceutical product, a drug for Gaucher's disease, is expected to be available soon.

    Plant Immunity and Genetic Engineering

    • Crops are vulnerable to plant viruses which can harm growth and yield.

    • Plant vaccines, similar to human vaccines, use weakened virus strains to stimulate a plant's defenses.

    • Plant vaccines can be encoded in the plant's DNA, eliminating the need for injections.

    • A gene from tobacco mosaic virus (TMV) can be inserted into tobacco plants, creating TMV-resistant plants.

    Genetic Pesticides

    • Bacillus thuringiensis (Bt) produces a protein that kills harmful insects by breaking down their digestive tract lining.

    • The Cry gene, responsible for Bt's insecticidal activity, is being incorporated into crops to create "insect-resistant" plants.

    Golden Rice and Nutrition

    • Golden Rice, genetically modified to produce beta carotene, offers a potential solution for vitamin A deficiency, which can lead to blindness.

    • While promising, genetically modified foods have limitations, such as the need for adequate fat intake to utilize the provitamin in Golden Rice.

    • Some groups advocate for conventional breeding methods like Harvest Plus, which aims to improve nutrient content in crops.

    • Other groups, like the Bill and Melinda Gates Foundation, support transgenic crops for combating malnutrition.

    The Future of Plant Biotechnology in Pharmacology

    • Plants can serve as efficient protein factories, with transgenic corn being particularly cost-effective.

    • In the future, farmers may grow human medicine along with traditional crops.

    • Edible vaccines can be produced by incorporating genes for viral or bacterial subunits into plants, allowing humans to ingest the vaccine with the plant.

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    Description

    Explore the innovative world of plant-based vaccines and biotechnology. This quiz covers the development of edible vaccines, the use of plants as factories for producing complex therapeutic proteins, and the potential of molecular farming in treating diseases. Test your knowledge on how these advancements could revolutionize pharmaceuticals and healthcare access.

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