Podcast
Questions and Answers
What are some examples of drugs that are substrates for CYP2C9 isoenzyme?
What are some examples of drugs that are substrates for CYP2C9 isoenzyme?
Ibuprofen, warfarin, tolbutamide
Which enzyme is responsible for the metabolism of codeine, metoprolol, and debrisoquine?
Which enzyme is responsible for the metabolism of codeine, metoprolol, and debrisoquine?
CYP2D6
Name an example of an inhibitor of CYP2C9 isoenzyme.
Name an example of an inhibitor of CYP2C9 isoenzyme.
Amiodarone
What is the main location of cytochrome P450 (CYP450) oxidase enzymes?
What is the main location of cytochrome P450 (CYP450) oxidase enzymes?
Which phase of metabolism involves oxidations, reductions, hydrolysis, and glucuronide conjugation?
Which phase of metabolism involves oxidations, reductions, hydrolysis, and glucuronide conjugation?
What are some examples of nonmicrosomal drug metabolizing enzymes?
What are some examples of nonmicrosomal drug metabolizing enzymes?
Which P450 isoenzyme is responsible for metabolizing ciclosporin, nifedipine, indinavir, and simvastatin?
Which P450 isoenzyme is responsible for metabolizing ciclosporin, nifedipine, indinavir, and simvastatin?
What is the genetic variation that leads to different acetylation rates in acetyl transferase?
What is the genetic variation that leads to different acetylation rates in acetyl transferase?
Name an example of an inducer of CYP2D6 isoenzyme.
Name an example of an inducer of CYP2D6 isoenzyme.
Which drug is a substrate for CYP2C9 isoenzyme and also for CYP3A4 isoenzyme?
Which drug is a substrate for CYP2C9 isoenzyme and also for CYP3A4 isoenzyme?
