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Questions and Answers
What is the primary function of the cell membrane?
What is the primary function of the cell membrane?
How does cholesterol affect the cell membrane at different temperatures?
How does cholesterol affect the cell membrane at different temperatures?
What characteristic makes phospholipids important components of the cell membrane?
What characteristic makes phospholipids important components of the cell membrane?
What is the primary role of protein channels in the cell membrane?
What is the primary role of protein channels in the cell membrane?
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What components make up the cytoskeleton?
What components make up the cytoskeleton?
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What is the primary function of the Golgi apparatus?
What is the primary function of the Golgi apparatus?
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Which component of a negative feedback control system is responsible for interpreting input from sensors?
Which component of a negative feedback control system is responsible for interpreting input from sensors?
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Which fluid is found inside the cells and is known as intracellular fluid (ICF)?
Which fluid is found inside the cells and is known as intracellular fluid (ICF)?
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What does the term 'set point' refer to in a negative feedback control system?
What does the term 'set point' refer to in a negative feedback control system?
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What best describes selective permeability in a cell membrane?
What best describes selective permeability in a cell membrane?
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Study Notes
Composition of a Cell Membrane
- Cell Membrane: Composed of phospholipid molecules; regulates substance entry and exit.
- Structure Impact on Transport: Features a glycerol hydrophilic head and hydrophobic fatty acid tails.
- Cholesterol Role: Prevents tight packing in low temperatures and reduces leakiness in high temperatures.
- Semipermeability: Allows passage of O2 and CO2 but blocks glucose and sugars.
- Phospholipid Molecule: Contains hydrophilic head and hydrophobic tails; amphiphilic nature is essential for membrane formation.
- Protein Channels: Facilitate selective transport through passive diffusion without energy expenditure.
- Cytoskeleton: Provides structural stability through proteins like microfilaments and microtubules; enables cell shape changes.
- Intracellular Fluid: Composed of cytosol; medium for cellular reactions.
Organelles and Their Functions
- Cell Membrane: Regulates substance exchange.
- Nucleus: Houses genetic material (DNA and genes).
- Ribosomes: Synthesize proteins using mRNA.
- Endoplasmic Reticulum: Rough ER synthesizes proteins; Smooth ER produces lipids and steroid hormones.
- Golgi Apparatus: Modifies and packages proteins/lipids from the ER for transport.
- Transport Vesicles: Aid movement of materials within the cell.
- Mitochondria: Produce energy (ATP) for the cell.
Homeostasis
- Definition: Maintenance of a stable internal environment critical for physiological functions.
- Key Values: Blood glucose level at 90 mg/ml, body temperature at 98.4°F.
- Steady State vs. Homeostasis: Steady state indicates constancy but does not imply homeostasis (e.g., during exercise).
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Negative Feedback Components:
- Controlled Variable: Maintained within narrow limits.
- Set Point: Target value for control processes.
- Sensors: Monitor changes in controlled variables.
- Comparator: Identifies deviations and initiates responses.
- Effectors: Restore the controlled variable to its set point.
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Intracellular vs. Extracellular Fluid:
- Intracellular Fluid (ICF): Fluid within cells.
- Extracellular Fluid (ECF): Fluid outside cells, subdivided into interstitial fluid and blood plasma.
Cell Membrane Transport Mechanisms
- Selective Permeability: Regulates which substances can enter or exit the cell.
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Transport Mechanisms:
- Diffusion: Passive transport for small, nonpolar molecules (e.g., O2, CO2).
- Facilitated Diffusion: Utilizes transport proteins for larger, polar molecules.
- Osmosis: Movement of water across a semipermeable membrane from low to high solute concentration.
- Primary Active Transport: Uses ATP for sodium/potassium pump function.
- Secondary Active Transport: Utilizes electrochemical gradients without direct ATP use.
- Bulk Transport: Involves endocytosis (material uptake) and exocytosis (material expulsion).
Endocytosis and Exocytosis
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Endocytosis: Engulfing extracellular materials into cells.
- Phagocytosis: Engulfment of debris and dead cells.
- Pinocytosis: Capture of extracellular fluid and solutes.
- Receptor-Mediated Endocytosis: Absorption of specific proteins/hormones.
- Exocytosis: Expelling materials from cells.
Osmosis Importance
- Process: Responsible for maintaining cell shape by preventing swelling or shrinkage.
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Tonicity Terms:
- Isotonic: Equal solute and water concentration.
- Hypotonic: Low solute, high water concentration (can cause cell swelling).
- Hypertonic: High solute, low water concentration (can cause cell shrinkage).
Cellular Respiration
- Adenosine Triphosphate (ATP): Energy currency of the cell, formed through glycolysis, Krebs cycle, and electron transport chain (ETC).
- ATP-PC System: Provides energy for short bursts of activity (e.g., sprinting) by breaking down ATP and phosphocreatine.
- Glycolysis: Anaerobic process breaking glucose into two pyruvate molecules, yielding two ATP; occurs in the cytoplasm.
- Citric Acid Cycle (Krebs Cycle): Produces energy equivalents (GTP, NADH, FADH2) and generates ATP (30-32 ATP total).
- Electron Transport Chain (ETC): Transfers electrons, creating a proton gradient to synthesize ATP.
- Oxidative Phosphorylation: ATP production via electron donation from NADH and FADH2.
- Aerobic Activity: Long-distance running and cycling predominantly utilize aerobic ATP production.
- Nutrient Utilization: The body primarily uses carbohydrates for short-term energy and fats for prolonged exercise.
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Description
This learning guide focuses on the key concepts of human physiology, specifically the composition and function of cell membranes. It serves as a structured aid to enhance understanding of the material presented during the module. Use this resource to build foundational knowledge for future content in the course.