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What is the main purpose of negative feedback in the body?
What is the main purpose of negative feedback in the body?
Homeostasis is a state of equilibrium that does not change.
Homeostasis is a state of equilibrium that does not change.
False
List the levels of organization in the human body from atoms to organism.
List the levels of organization in the human body from atoms to organism.
Atoms → Molecules → Cells → Tissues → Organs → Organ Systems → Organism
The maintenance of a relatively stable internal environment is called __________.
The maintenance of a relatively stable internal environment is called __________.
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Which of the following is NOT a characteristic of simple diffusion?
Which of the following is NOT a characteristic of simple diffusion?
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Match the type of transport with its description:
Match the type of transport with its description:
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An example of active transport is the movement of glucose through GLUT transporters.
An example of active transport is the movement of glucose through GLUT transporters.
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What occurs when homeostasis fails for prolonged periods?
What occurs when homeostasis fails for prolonged periods?
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Which hormone is primarily involved in regulating circadian rhythms?
Which hormone is primarily involved in regulating circadian rhythms?
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The hypothalamus does not produce neurohormones that regulate the pituitary gland.
The hypothalamus does not produce neurohormones that regulate the pituitary gland.
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What is the main target of Prolactin (PRL)?
What is the main target of Prolactin (PRL)?
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The hormone that stimulates the adrenal cortex is called __________.
The hormone that stimulates the adrenal cortex is called __________.
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Match the following anterior pituitary hormones with their corresponding control hormones:
Match the following anterior pituitary hormones with their corresponding control hormones:
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Long-loop negative feedback primarily involves which hormones?
Long-loop negative feedback primarily involves which hormones?
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Functional antagonism refers to different hormones working together to produce a greater effect.
Functional antagonism refers to different hormones working together to produce a greater effect.
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What does permissiveness mean in the context of hormone interaction?
What does permissiveness mean in the context of hormone interaction?
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What is a key difference in the response time between lipophilic and lipophobic ligands binding to their respective receptors?
What is a key difference in the response time between lipophilic and lipophobic ligands binding to their respective receptors?
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Neurotransmitters are chemical signals used in endocrine reflexes.
Neurotransmitters are chemical signals used in endocrine reflexes.
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Name one type of receptor that binds to epinephrine and its effect.
Name one type of receptor that binds to epinephrine and its effect.
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The speed of neural reflexes is considered to be very ______.
The speed of neural reflexes is considered to be very ______.
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Match the type of hormone to its characteristic:
Match the type of hormone to its characteristic:
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What term describes the process by which receptors convert physical stimuli into electrical signals?
What term describes the process by which receptors convert physical stimuli into electrical signals?
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What is the coding method for stimulus intensity in neural reflexes?
What is the coding method for stimulus intensity in neural reflexes?
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Peptide hormones are lipophilic and can easily pass through the cell membrane.
Peptide hormones are lipophilic and can easily pass through the cell membrane.
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Tonic receptors adapt quickly to a continuous stimulus.
Tonic receptors adapt quickly to a continuous stimulus.
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List one criterion that makes a chemical signal a hormone.
List one criterion that makes a chemical signal a hormone.
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Define a motor unit.
Define a motor unit.
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The __________ reflex is an example of a monosynaptic stretch reflex.
The __________ reflex is an example of a monosynaptic stretch reflex.
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Match the following neurotransmitters to their respective divisions:
Match the following neurotransmitters to their respective divisions:
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Which of the following factors influences stroke volume?
Which of the following factors influences stroke volume?
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Blood pressure decreases as blood flows through the systemic circulation.
Blood pressure decreases as blood flows through the systemic circulation.
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Explain the relationship between heart rate and stroke volume.
Explain the relationship between heart rate and stroke volume.
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What type of hormonal interaction occurs when two hormones produce a greater effect together than individually?
What type of hormonal interaction occurs when two hormones produce a greater effect together than individually?
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Hyposecretion is characterized by excess hormone production.
Hyposecretion is characterized by excess hormone production.
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Name the three most common types of endocrine pathologies.
Name the three most common types of endocrine pathologies.
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In a three-gland pathway, high hormone levels at the final gland indicate a problem may be in the _______ or _______.
In a three-gland pathway, high hormone levels at the final gland indicate a problem may be in the _______ or _______.
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Match the following hormones with their effects:
Match the following hormones with their effects:
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What occurs when target cells fail to respond appropriately to hormones?
What occurs when target cells fail to respond appropriately to hormones?
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An increase in thyroid hormone paired with a decrease in TSH indicates a problem with the thyroid gland.
An increase in thyroid hormone paired with a decrease in TSH indicates a problem with the thyroid gland.
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The mechanism of long-term potentiation in synaptic communication is mediated by _______ and _______ receptors.
The mechanism of long-term potentiation in synaptic communication is mediated by _______ and _______ receptors.
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What is the primary factor that increases blood pressure according to the relationship between cardiac output and peripheral resistance?
What is the primary factor that increases blood pressure according to the relationship between cardiac output and peripheral resistance?
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Myogenic autoregulation is responsible for decreasing blood flow when blood pressure increases.
Myogenic autoregulation is responsible for decreasing blood flow when blood pressure increases.
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What are the two types of signaling that the body uses to direct blood flow?
What are the two types of signaling that the body uses to direct blood flow?
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The _____ reflex helps regulate blood pressure through changes in heart rate and vessel diameter.
The _____ reflex helps regulate blood pressure through changes in heart rate and vessel diameter.
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Match the following cellular elements of blood with their primary functions:
Match the following cellular elements of blood with their primary functions:
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Which condition describes the relationship between lung volume and pressure during inhalation?
Which condition describes the relationship between lung volume and pressure during inhalation?
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Compliance and elastance are two measures that describe the same physiological property of the lungs.
Compliance and elastance are two measures that describe the same physiological property of the lungs.
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What role do surfactants play in respiratory physiology?
What role do surfactants play in respiratory physiology?
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Study Notes
Chapter 1
- Physiology is the study of the normal functioning of a living organism and its parts.
- Levels of organization: Atoms → Molecules → Cells → Tissues → Organs → Organ Systems → Organism
- Homeostasis is maintaining a stable internal environment despite external changes. Disease occurs when homeostasis is disrupted for prolonged periods.
- Negative feedback: A process that reverses a change to return to a set point. Example: Body temperature regulation (sweating when it's hot).
- Positive feedback: A process that amplifies or increases a change, moving the system further from the set point. Example: Childbirth (oxytocin intensifies contractions).
- Feedforward control: Anticipates changes and activates mechanisms to prevent deviations. Example: Salivation before eating.
Chapter 5
- Osmotic equilibrium: Total solute concentration is the same on both sides of the cell membrane, resulting in no net water movement.
- Chemical disequilibrium: Uneven distribution of solutes (e.g., Na+, K+, Cl-) across the cell membrane.
- Electrical disequilibrium: Charge differences across the membrane, typically around -70 mV. Maintained by ion channels and pumps like Na+/K+ ATPase.
- Simple diffusion: Passive movement down a concentration gradient (e.g., oxygen and carbon dioxide). No energy or proteins required.
- Protein-mediated transport: Includes facilitated diffusion, active transport, and ion channels. Facilitated diffusion is passive, using carrier proteins to move molecules down their concentration gradient. Active transport requires ATP to move molecules against their gradient. Ion channels facilitate the passage of specific ions.
- Vesicular transport: Active process involving vesicles (e.g., exocytosis, endocytosis, phagocytosis). Energy is required for vesicle formation and movement.
General Principles of Transport
- Specificity: Certain transporters only move specific molecules.
- Competition: Similar molecules can compete for the same transporter.
- Saturation: High substrate concentrations reach a maximum transport rate (Tmax).
- Carrier-mediated transport principles apply to receptors and ligands. (Specificity, Competition, Affinity, Saturation).
Membrane Potential
- Ion permeability changes membrane potential.
- Increased Na+ permeability depolarizes the membrane.
- Increased K+ permeability repolarizes the membrane.
- Decreased Cl− permeability can also affect the membrane potential if the equilibrium potential is more negative than the resting potential
- Opposite charges attract, like charges repel. Separating opposite charges requires energy.
Chapter 6
- Local communication:
- Gap junctions: Direct cytoplasmic connections.
- Contact-dependent signals: Require cell-to-cell contact.
- Diffusing chemicals: Paracrine signaling (e.g., histamine, affecting nearby cells).
- Long-distance communication:
- Blood transport: Endocrine system (e.g., hormones like insulin).
- Neurochemicals: Neurotransmitters (e.g., in synaptic clefts).
Hormone Actions
- Lipophilic ligands (e.g., steroids) diffuse through the membrane, bind to intracellular receptors, activating DNA binding and gene expression, leading to new protein synthesis. This is a slower response.
- Lipophobic ligands (e.g., peptides) bind to surface receptors, activating intracellular signaling pathways, and generating second messengers (e.g., cAMP, Ca++). This leads to rapid changes in cellular activity.
Cell Surface Receptors
- Chemically gated (ligand-gated) ion channels (e.g., nicotinic ACh receptors).
- G protein-coupled receptors (GPCRs)(e.g., adrenergic receptors).
- Receptor-enzyme complexes (e.g., receptor tyrosine kinases).
- Integrin receptors (e.g., integrins in cell adhesion).
Endocrine Reflexes
- Stimulus: detected by a receptor.
- Sensor: detects the stimulus.
- Input signal: travels to integrating center.
- Integrating center: processes and determines a response.
- Output signal: travels to target via efferent pathways.
- Target: the cell or organ that carries out the response.
- Response occurs to restore homeostasis
Comparing Neural and Endocrine Reflexes
- Neural reflexes are very fast (milliseconds), with discrete, highly specific targets, and use electrical and chemical signals.
- Endocrine reflexes are slower (minutes to hours), affect many cells through the bloodstream, use chemical signals (hormones), and have a longer duration.
Endocrine Pathologies
- Hypersecretion: excessive hormone production.
- Hyposecretion: insufficient hormone production.
- Abnormal target response: failure of the target cell response.
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Description
Test your knowledge on the fundamental concepts of physiology, including levels of organization and homeostasis. This quiz covers important processes like feedback mechanisms and osmotic equilibrium, essential for understanding how living organisms function. Perfect for students in biology or related fields.