Physics Lecture 1: Nobel Prize Winners in NMR

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Questions and Answers

What was the Nobel Prize awarded to Lauterbur and Sir Peter Mansfield for?

  • Their work on the development of ultrasound machines
  • Their discoveries concerning magnetic resonance imaging (correct)
  • Their discoveries in the field of X-ray technology
  • Their research on the treatment of cancer

Who were the two scientists awarded the Nobel Prize in Medicine?

  • Lauterbur and Sir Charles Darwin
  • Lauterbur and Sir Isaac Newton
  • Lauterbur and Sir Alexander Flemming
  • Lauterbur and Sir Peter Mansfield (correct)

What is the field of medicine that Lauterbur and Sir Peter Mansfield were awarded the Nobel Prize in?

  • Medicine (correct)
  • Neurology
  • Cardiology
  • Physiology

What is the name of the imaging technology that Lauterbur and Sir Peter Mansfield were awarded the Nobel Prize for?

<p>Magnetic Resonance Imaging (MRI) (B)</p> Signup and view all the answers

What is the primary function of fMRI?

<p>To map the function of different areas of the human brain (B)</p> Signup and view all the answers

What is the language of the given text in addition to English?

<p>Arabic (B)</p> Signup and view all the answers

What is the name of the person who developed fMRI?

<p>Paul C. (A)</p> Signup and view all the answers

In what year was fMRI developed?

<p>2003 (B)</p> Signup and view all the answers

What does fMRI stand for?

<p>Functional Magnetic Resonance Imaging (D)</p> Signup and view all the answers

What is the main advantage of fMRI over other brain imaging techniques?

<p>It allows for mapping of brain function (D)</p> Signup and view all the answers

Who discovered the magnetic resonance phenomenon independently?

<p>Felix Bloch and Edward Purcell (B)</p> Signup and view all the answers

What was developed and used for chemical and physical molecular analysis between 1950 and 1970?

<p>Nuclear Magnetic Resonance (NMR) (A)</p> Signup and view all the answers

Who showed that the nuclear magnetic relaxation times of tissues and tumors differed?

<p>Raymond Damadian (C)</p> Signup and view all the answers

Who introduced the x-ray-based computerized tomography (CT) in 1973?

<p>Godfrey Hounsfield (A)</p> Signup and view all the answers

Who proposed magnetic resonance imaging using phase and frequency encoding, and the Fourier Transform?

<p>Richard Ernst (B)</p> Signup and view all the answers

Who developed the echo-planar imaging (EPI) technique?

<p>Peter Mansfield (D)</p> Signup and view all the answers

When was functional magnetic resonance imaging (fMRI) developed?

<p>1992 (A)</p> Signup and view all the answers

Who perfected magnetic resonance angiography (MRA) without the use of contrast agents?

<p>Charles Dumoulin (A)</p> Signup and view all the answers

What was used to perform real-time movie imaging of a single cardiac cycle in 1987?

<p>Echo-planar imaging (EPI) (D)</p> Signup and view all the answers

When was the imaging time reduced to about five seconds and 10μm?

<p>1986 (C)</p> Signup and view all the answers

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Study Notes

Magnetic Resonance Imaging (MRI) Development

  • Felix Bloch and Edward Purcell were awarded the Nobel Prize in 1952 for discovering the magnetic resonance phenomenon independently.
  • Between 1950 and 1970, NMR was developed and used for chemical and physical molecular analysis.
  • In 1971, Raymond Damadian showed that the nuclear magnetic relaxation times of tissues and tumors differed.
  • In 1973, the x-ray-based computerized tomography (CT) was introduced by Hounsfield, and Magnetic Resonance Imaging (MRI) was first demonstrated on small test tube samples by Paul Lauterbur.
  • Lauterbur used a back projection technique similar to that used in CT scans.

Advances in MRI Technology

  • In 1975, Richard Ernst proposed magnetic resonance imaging using phase and frequency encoding, and the Fourier Transform.
  • In 1977, Raymond Damadian demonstrated MRI called field-focusing nuclear magnetic resonance, and Peter Mansfield developed the echo-planar imaging (EPI) technique.
  • In 1980, Edelstein and coworkers demonstrated imaging of the body using Ernst's technique.
  • In 1986, the imaging time was reduced to about five seconds and 10 μm.
  • In 1987, echo-planar imaging was used to perform real-time movie imaging of a single cardiac cycle.

Advancements and Recognition

  • Charles Dumoulin was perfecting magnetic resonance angiography (MRA) without the use of contrast agents.
  • In 1992, functional magnetic resonance imaging (fMRI) was developed, allowing mapping of the function of different areas of the human brain.
  • In 2003, Paul C. Lauterbur and Sir Peter Mansfield were awarded the Nobel Prize in Medicine for their discoveries concerning magnetic resonance imaging.

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