Physical Pharmacy Practice Questions
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Questions and Answers

Which equation is also known as the buffer equation?

  • Henderson-Hasselbalch (correct)
  • Noyes-Whitney
  • Van’t Hoff
  • Arrhenius
  • The dissolution of a drug is calculated using which equation?

  • Henderson-Hasselbalch
  • Stokes
  • Arrhenius
  • Noyes-Whitney (correct)
  • To increase the miscibility of partially miscible liquids, what kind of substance should be added?

  • immiscible with both liquids
  • miscible with both liquids
  • miscible with one of the liquids (correct)
  • immiscible with one of the liquids
  • What happens to the vapor pressure of a solution in the presence of a solute?

    <p>lowered</p> Signup and view all the answers

    What is the number of gram equivalents of solute per liter of solution called?

    <p>normality</p> Signup and view all the answers

    In which crystalline form does NaCl exist?

    <p>cubic</p> Signup and view all the answers

    Which diffusion mechanism involves the transport of drugs from a region of high to low concentration?

    <p>Passive</p> Signup and view all the answers

    Which statement about dustibility is NOT true?

    <p>It signifies the opposite of stickness</p> Signup and view all the answers

    Which equation reveals the rate of diffusion of a drug?

    <p>Fick’s First Law</p> Signup and view all the answers

    What is the contact angle between a liquid droplet and the surface when complete wetting occurs?

    <p>0º</p> Signup and view all the answers

    What do gels and magmas form when standing, and what do they become on shaking?

    <p>Dilatant and Thixotropic</p> Signup and view all the answers

    What type of forces exist between polar molecules with dipole movement?

    <p>Keesom Forces</p> Signup and view all the answers

    What is the term for the existence of elemental substances in more than one crystalline form?

    <p>Polymorphism</p> Signup and view all the answers

    Which method is used to measure tonicity based on the effect on red blood cells suspended in solutions?

    <p>Hemolytic Method</p> Signup and view all the answers

    Which law expresses the effect of pressure on the solubility of a gas?

    <p>Henry’s Law</p> Signup and view all the answers

    What type of interaction involves the attractive interaction between a polar molecule and the induces dipole?

    <p>Dipole-Induced Dipole Interaction</p> Signup and view all the answers

    Study Notes

    Pharmaceutical Calculations

    • The Henderson-Hasselbalch equation is also known as the buffer equation.
    • The Noyes-Whitney equation is used to calculate the dissolution of a drug.

    Solubility and Miscibility

    • To increase the miscibility of partially miscible liquids, a solubilizer or a co-solvent should be added.
    • The vapor pressure of a solution decreases in the presence of a solute.

    Solutions and Concentration

    • The number of gram equivalents of solute per liter of solution is called normality.
    • NaCl exists in a face-centered cubic crystalline form.

    Diffusion and Transport

    • Passive diffusion involves the transport of drugs from a region of high to low concentration.
    • Fick's law of diffusion reveals the rate of diffusion of a drug.

    Physical Properties

    • A contact angle of 0° is observed when complete wetting occurs between a liquid droplet and the surface.
    • Gels and magmas form a sediment when standing, and become a uniform mixture on shaking.

    Intermolecular Forces

    • Polar molecules with dipole movement exhibit dipole-dipole forces.
    • Polymorphism is the term for the existence of elemental substances in more than one crystalline form.

    Osmometry and Solubility

    • The haemolysis method is used to measure tonicity based on the effect on red blood cells suspended in solutions.
    • Henry's law expresses the effect of pressure on the solubility of a gas.
    • Induced dipole forces involve the attractive interaction between a polar molecule and the induced dipole.

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    Test your knowledge of physical pharmacy with these practice questions. Topics include buffer equation, dissolution of drugs, and more.

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