Physical Pharmacy: Ionic Equilibria and Acid-Base Theories

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20 Questions

Which theory defines an acid as a substance that liberates hydrogen ions and a base as a substance that supplies hydroxyl ions on dissociation in aqueous media?

Arrhenius theory

According to the Bronsted-Lowry theory, what is an acid?

A substance that donates a proton

In which solvent is HCI considered a weak acid?

Glacial acetic acid

Which theory defines an acid as a molecule or an ion that accepts an electron pair to form a covalent bond?

Lewis Electronic Theory

Which of the following is classified as a Lewis base according to the Lewis definition?

Amines

What type of bond is formed when a Lewis acid accepts an electron pair from a Lewis base?

Covalent bond

Which of the following can be classified as a Lewis base?

Ammonia (NH3)

What is the role of an acid according to the Arrhenius theory?

Liberates hydrogen ions

Which type of solvent is capable of accepting protons from the solute?

Protophilic solvent

Which type of solvent is a proton-donating compound?

Protogenic solvent

Which class of solvents act as both proton acceptors and proton donors?

Amphiprotic solvents

Which type of solvents neither accept nor donate protons?

Aprotic solvents

What is the pH value representing the neutral point?

7 at room temperature

What is the term for the autoprotolysis constant or ion product of water?

Ionic equilibria Kw

What is the pH at which zwitterion concentration is at its maximum?

IEP (Isoelectric point)

What is the net charge of a molecule at its Isoelectric point (IEP)?

-1

What is the charge of a molecule at pH above its Isoelectric point (IEP)?

+1

What is the charge of a molecule at pH below its Isoelectric point (IEP)?

-2

In the measurement of pH, what happens with a strong acid concentration?

Concentration of H is equal to initial concentration of acid.

In solutions containing a single conjugate acid-base pair, what example illustrates the measurement of pH?

Example 7-16 and 17

This quiz covers the study of ionic equilibria in physical pharmacy, including acid-base theories, calculation of pH, and acidity constants. It explores the Arrhenius and Bronsted-Lowry theories of acids and bases.

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