20 Questions
What are the three main components of a phospholipid?
Hydrocarbon chain, glycerol, and phosphate-alcohol head group
Which is the most common phosphoglyceride found in the cell membrane?
Phosphatidylcholine
What is the basic structure of a phospholipid?
Phosphatidic acid
What is the role of the transfer molecule CDP in phospholipid synthesis?
To transfer a phosphate group to the glycerol backbone
How do phospholipids synthesized in the smooth ER reach the plasma membrane?
Via vesicle transport
What is the classification of sphingomyelin?
Sphingolipid
Which class of lipids contains phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine?
Glycerophospholipids
What is the name of the phospholipid that has one fatty acid linked to the glycerol backbone with an ester link, while the other fatty acid has an ether link?
Plasmalogen
What is the cellular location of phospholipid synthesis?
Smooth ER
What is the first step in phospholipid synthesis?
Synthesis of glycerol backbone
What is the second step in phospholipid synthesis?
Attachment of fatty acids to backbone
What is the third step in phospholipid synthesis?
Addition of head group
What is the fourth step in phospholipid synthesis?
Exchange/modification of head group
Which molecule is used to activate one of the hydroxyl groups during the addition of the head group in phospholipid synthesis?
Cytosine diphosphate (CDP)
What is the role of flippase in phospholipid synthesis?
Translocation of phospholipids across the ER membrane
Which of the following is NOT a step in phospholipid synthesis?
Exchange/modification of fatty acids
Which nucleotide is used as a methyl donor in the conversion of phosphatidylethanolamine to phosphatidylcholine?
S-adenosylmethionine (SAM)
Where does phospholipid synthesis primarily occur?
Smooth ER
Which phospholipid plays an important role in cell signaling?
Phosphatidylinositol
How are phosphatidylserine and phosphatidylethanolamine interconverted?
By exchange of head groups
Test your knowledge on phospholipids with this quiz! Learn to classify phospholipids based on their structural group, identify the main components of a phospholipid, and name the most common phosphoglycerides found in the cell membrane. Understand the cellular location and basic steps of phospholipid synthesis.
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