Phineas Gage Case Study

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Questions and Answers

What personality changes did Phineas Gage experience after his accident?

  • He lost interest in alcohol.
  • He was more responsible and sociable.
  • He became impatient and obstinate. (correct)
  • He became more efficient and capable.

What is a symptom of pseudodepression associated with left frontal lobe lesions?

  • Engagement in social activities.
  • Loss of initiative. (correct)
  • Heightened sexual interest.
  • Increased social abilities.

Which behavior is associated with pseudopsychopathy linked to right frontal lobe lesions?

  • Promiscuous sexual behavior. (correct)
  • Strong impulse control.
  • Increased financial responsibility.
  • Verbal restraint.

What year did Moniz initiate psychosurgery with frontal lobotomies?

<p>1935 (C)</p> Signup and view all the answers

What was the goal of the transorbital leucotomy developed by Freeman?

<p>To alleviate psychiatric symptoms. (A)</p> Signup and view all the answers

Which aspect of Phineas Gage's accident was unusual regarding his consciousness?

<p>He never lost consciousness. (A)</p> Signup and view all the answers

What is a common effect of lesions in the ventral prefrontal lobes?

<p>Increases in impulsive behavior. (B)</p> Signup and view all the answers

What physical evidence remained after the accident involving Phineas Gage?

<p>The tamping iron was recovered. (C)</p> Signup and view all the answers

Which brain region is activated by facial expressions of disgust?

<p>Insula (A)</p> Signup and view all the answers

Which of the following statements is true regarding left hemisphere lesions in patients?

<p>They tend to show depressive-catastrophic reactions. (C)</p> Signup and view all the answers

What reaction is typically observed with right hemisphere inactivation during emotional testing?

<p>Indifference and sarcasm (D)</p> Signup and view all the answers

What physical sensation can be caused by electrical stimulation of the insula?

<p>Nausea (D)</p> Signup and view all the answers

In the context of emotional processing, which hemisphere is primarily associated with negative emotions?

<p>Right hemisphere (B)</p> Signup and view all the answers

What type of expressions activate the amygdala, according to the studies?

<p>Fearful expressions (C)</p> Signup and view all the answers

What is a known association of disgust in terms of sensory experience?

<p>Bad taste associated with food (A)</p> Signup and view all the answers

During the Wada test, what reaction is linked to left inactivation?

<p>Catastrophic reactions (B)</p> Signup and view all the answers

What is the primary task in the target detection exercise presented?

<p>Identify the position of the target 'T' (C)</p> Signup and view all the answers

What effect does the arrangement of the targets and distractors have on the task?

<p>It increases the time needed to identify the target (B)</p> Signup and view all the answers

Which of the following statements is true regarding target detection?

<p>Target detection can require significant time (A)</p> Signup and view all the answers

In Treisman & Gelade's study, what may be inferred about the positioning of 'T's and 'X's?

<p>Their arrangement affects how easily the target can be found (D)</p> Signup and view all the answers

What implication can be drawn from the repeated phrase 'Find the T' in the content?

<p>It suggests that target recognition can vary but remains constant in instruction (D)</p> Signup and view all the answers

What is a strength of the experiment related to the pairing of targets?

<p>Spiders and snakes were paired with similar-looking non-dangerous creatures. (A)</p> Signup and view all the answers

Which limitation of the experiment could affect the results?

<p>It didn't measure people's fear of snakes or spiders. (D)</p> Signup and view all the answers

What phenomenon is observed in fearful participants regarding attention?

<p>They struggle more to disengage from threatening stimuli. (D)</p> Signup and view all the answers

What procedural aspect aimed to eliminate handedness effects in the study?

<p>Targets were balanced between the left and right sides. (D)</p> Signup and view all the answers

What distinguishes divergent thinking from convergent thinking?

<p>Divergent thinking allows for multiple responses. (B)</p> Signup and view all the answers

Why is the strength of randomizing trial order important?

<p>It prevents participants from anticipating stimuli sequences. (C)</p> Signup and view all the answers

What aspect of behavior is decreased with frontal lobe injury?

<p>Overall behavior including spontaneity. (B)</p> Signup and view all the answers

What does the Stroop test primarily measure?

<p>Inhibition and cognitive control. (C)</p> Signup and view all the answers

How are the Wisconsin Card Sorting Test cards meant to be categorized?

<p>By either number, shape, or color. (C)</p> Signup and view all the answers

Which area is primarily associated with divergent thinking?

<p>Dorsolateral prefrontal area. (D)</p> Signup and view all the answers

What finding was observed in patients with a left frontal lesion while performing the Stroop test?

<p>Impairment in inhibition tasks. (A)</p> Signup and view all the answers

Which cognitive skill is assessed by tasks that require producing words starting with specific letters?

<p>Verbal fluency. (A)</p> Signup and view all the answers

Who demonstrated that patients with prefrontal dorsolateral lesions were impaired in concept formation?

<p>Milner. (B)</p> Signup and view all the answers

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Study Notes

Phineas Gage’s Case

  • In 1848, a tamping iron went through Phineas Gage’s skull, destroying his frontal lobes.
  • Phineas Gage survived the accident and appeared to have no loss of consciousness.
  • After the accident, his personality changed drastically.
  • He became irresponsible, lacking social graces, and unable to hold a job.
  • He was no longer the efficient and capable foreman he was before the accident.

Symptoms of Frontal Lobe Lesions

  • Impaired social and sexual behavior
  • Changes in personality

Pseudodepression

  • Appears after lesions of the left frontal lobe.
  • Symptoms include outward apathy, indifference, loss of initiative, reduced sexual interest, and little verbal output.

Pseudopsychopathy

  • Appears after lesions of the right frontal lobe.
  • Symptoms include immature behavior, lack of tact and restraint, promiscuous sexual behavior, coarse language, lack of social graces, and increased motor activity.

Effect of Ventral Prefrontal Lobes on Emotion

  • Psychosurgery was initiated in 1935 by Moniz, aiming to alleviate psychiatric symptoms through frontal lobotomies.
  • The procedure was widely used without scientific evidence.
  • In 1945, Freeman developed a simplified procedure called “transorbital leucotomy,” also known as the ice-pick lobotomy, which was used on tens of thousands of people.

Insula Responds to Disgust

  • The insula is activated by facial expressions of disgust.
  • The gustatory cortex is located in the insula, leading to associations between disgust and bad food.
  • Electrical stimulation of the insular region can cause nausea.
  • Epileptic auras that present as a “bad taste” or nausea often originate in the insula.

Hemispheric Asymmetry in Emotions

  • Right inactivation leads to euphoric-maniacal reactions.
  • Left inactivation leads to depressive-catastrophic reactions.
  • The left hemisphere is thought to house positive emotions while the right hemisphere houses negative emotions.

Hemsipheric Asymmetry in Emotions

  • Patients left hemisphere lesions tend to show catastrophic reactions when confronted with their difficulties.
  • Patients with right hemisphere lesions can be indifferent, unaware of their difficulties, disinhibited, and even euphoric.

Dorsolateral Prefrontal Area

  • Divergent thinking generates many responses to a question.
  • Convergent thinking leads to one answer to a question.
  • Frontal lobe injury disrupts divergent thinking.

The Dorsolateral Prefrontal Area: Divergent Thinking

  • Verbal fluency is measured by the number of words a patient can produce starting with a specific letter.
  • Figural fluency is measured by a patient’s ability to produce multiple drawings.

The Dorsolateral Prefrontal Area: Inhibition

  • The Stroop Test measures a patient’s ability to read the color of font instead of the word itself.
  • Patients with left frontal lesions perform poorly on the Stroop Test.

The Dorsolateral Prefrontal Area: Concept Formation

  • The Wisconsin Card Sorting Test assesses a patient's ability to learn and adapt to changing rules in classifying cards.
  • Patients with prefrontal dorsolateral lesions perform poorly.

Target Detection

  • The ability to locate a specific target amongst distractors is tested using a Visual Search Task.
  • Target detection takes longer when more distractors are present.

Spider Fear Experiment

  • Participants with arachnophobia demonstrate attentional capture and distraction by spiders.
  • Spiders can be either the target or distractors in the Visual Search Task.
  • Fearful participants show stronger effects than non-fearful controls.

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