Phenazopyridine

Which organisms are most susceptible to fluoroquinolones?

Aerobic gram-positive organisms
Anaerobic organisms
Aerobic gram-negative organisms (correct)
Fungi

What is the recommended spacing for administering ciprofloxacin with antacids, multivitamins, sucralfate, or other products containing calcium, iron, or zinc?

4 to 6 hours (correct)
2 to 4 hours
1 to 2 hours
6 to 8 hours

What are the interactions of trimethoprim and sulfamethoxazole?

They enhance the effects of other antibiotics
They cause hypoglycemia
They increase the risk of GI bleeding
They inhibit specific cytochrome P450 enzymes (correct)

How does TMP-SMZ interact with warfarin?

It inhibits warfarin metabolism (B) Signup and view all the answers

What interactions can occur between TMP-SMZ and anticonvulsants?

Toxicity when taken in combination (D) Signup and view all the answers

In what case is TMP-SMZ administered parenterally?

Pneumocystis pneumonia (D) Signup and view all the answers

What should the nurse assess for when a patient is taking TMP-SMZ for a UTI?

Decreased symptoms of the UTI (D) Signup and view all the answers

Which of the following is the CDC's recommended regimen for the treatment of gonorrhea?

Ceftriaxone (D) Signup and view all the answers

Why does the CDC no longer recommend the use of fluoroquinolones for gonococcal disease?

Resistance to this antimicrobial has developed (B) Signup and view all the answers

Which of the following is NOT a multiple indication for ciprofloxacin?

Meningitis (D) Signup and view all the answers

What is the current recommendation for first-line treatment of suspected Bacillus anthracis infections?

Ciprofloxacin until culture and susceptibility results are available (A) Signup and view all the answers

What precautions should be taken when using fluoroquinolones in older adults with normal renal function?

Accompanied by an adequate fluid intake and urine output (C) Signup and view all the answers

What are some reported renal effects of ciprofloxacin?

Azotemia, crystalluria, and hematuria (A) Signup and view all the answers

How can nephrotoxicity be reduced when using ciprofloxacin?

Using lower dosages and longer intervals between doses (A) Signup and view all the answers

Which adverse effect is NOT associated with the use of ciprofloxacin?

Mild headache (B) Signup and view all the answers

What is the serious concern with the use of fluoroquinolones?

Tendon rupture (C) Signup and view all the answers

Who is at greater risk for adverse effects of fluoroquinolones?

People with heart, kidney, and lung transplants (C) Signup and view all the answers

What is the BLACK BOX WARNING for fluoroquinolones?

Increased risk of tendon rupture (C) Signup and view all the answers

What is the contraindication for ciprofloxacin use?

Hypersensitivity (A) Signup and view all the answers

Can ciprofloxacin be used during pregnancy?

Yes, for prophylaxis and treatment of pregnant women with anthrax exposure (D) Signup and view all the answers

What are the potential drug interactions with ciprofloxacin?

Drugs that reduce ciprofloxacin absorption (B) Signup and view all the answers

What should patients avoid while taking oral ciprofloxacin?

Dairy products or other calcium-containing foods (A) Signup and view all the answers

How should the IV formulation of ciprofloxacin be administered?

Over 60 minutes (C) Signup and view all the answers

Which of the following is the purpose of administering phenazopyridine?

To provide pain relief related to burning, urgency, frequency, and irritation of the lower urinary tract mucosa (A) Signup and view all the answers

What is the recommended use of trimethoprim in the treatment of P. jirovecii pneumonia?

Unlabeled use (C) Signup and view all the answers

What is the main route of elimination for ciprofloxacin?

Kidneys (B) Signup and view all the answers

What type of bacteria is ciprofloxacin most potent against?

Gram-negative (C) Signup and view all the answers

What is the mechanism of action of sulfonamides?

Interfering with folic acid reduction to tetrahydrofolate (D) Signup and view all the answers

Do sulfonamides kill mature, fully formed bacteria?

No (D) Signup and view all the answers

What precautions should be taken when administering TMP-SMZ to older adults?

Assess renal function and the risk of hyperkalemia (B) Signup and view all the answers