23 Questions
What is the primary reason for determining the solubility of a drug in pharmacy practice?
To choose the best solvent medium for the drug
What is the term for a solution that contains the maximum amount of solute that the solvent can hold at a given temperature?
Saturated solution
What is the unit of measurement for solubility as defined by the USP and NF?
Number of mL of solvent in which 1 g of solute will dissolve
What is the term for a solution that contains more solute than it can hold at a given temperature?
Supersaturated solution
What is the qualitative definition of solubility?
The spontaneous interaction of 2 or more substances to form a homogeneous molecular dispersion
What is the approximate solubility term for a substance that dissolves in 18 ml of water?
Freely soluble
What is the equivalent weight of HNO3?
63
What is the normality of a solution made by dissolving 8.5 g of H2SO4 in enough water to make 500 ml solution?
0.34
What is the ratio of solute to solvent in a saturated solution that contains 100 g of solute and 300 g of solvent?
1:3
What is the relationship between the normality and molarity of a solution?
The normality is never less than the molarity
What is the normality of a 3 M H2SO4 solution?
6 N
If 100 g of a saturated aqueous solution leaves a residue of 25 g after evaporation, what is the solubility of the anhydrous chemical?
1:3
What is the normality of a 0.01 M H2SO4 solution?
0.02 N
What is the weight of 100 mL of a saturated aqueous solution with a specific gravity of 1.15?
115 g
If a saturated aqueous solution has a strength of 20% (w/w), what is the solubility of the active ingredient?
1:4
What is the amount of solvent in a saturated solution that contains 25 g of solute and has a solubility of 1:3.6?
90 g
What is the solubility of a substance if 100 mL of a saturated aqueous solution contains 25 g of the substance?
1:3.6
What is the solubility of boric acid in water?
1 g in 4 g of water
What is the percentage strength (w/w) of a saturated aqueous solution of boric acid?
5.26%
What is the molar weight of Benzoic acid?
122 dalton
What is the purpose of adding phenolphthalein indicator in the procedure?
To detect the end point of the titration
What is the equivalent weight of salicylic acid in terms of 0.1 N NaOH?
0.0138 gm
What is the formula to calculate the solubility (%) of an acid?
mls of titrant X F X 20
This quiz covers the concepts of solubility, qualitative and quantitative definitions, and types of solutions, including unsaturated, saturated and supersaturated solutions, in the context of pharmacy. Understand the importance of solubility in pharmaceutical applications.
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