Pharmacy: Solubility and Solutions
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What is the primary reason for determining the solubility of a drug in pharmacy practice?

  • To establish the purity of the drug
  • To determine the quantitative definition of solubility
  • To identify the state of subdivision of the solute
  • To choose the best solvent medium for the drug (correct)

    • What is the term for a solution that contains the maximum amount of solute that the solvent can hold at a given temperature?

  • Homogeneous solution
  • Unsaturated solution
  • Supersaturated solution
  • Saturated solution (correct)

    • What is the unit of measurement for solubility as defined by the USP and NF?

  • Number of mL of solvent in which 1 mL of solute will dissolve
  • Number of grams of solvent in which 1 mL of solute will dissolve
  • Number of mL of solvent in which 1 g of solute will dissolve (correct)
  • Number of grams of solute in 1 mL of solvent

    • What is the term for a solution that contains more solute than it can hold at a given temperature?

    <p>Supersaturated solution</p> Signup and view all the answers

    What is the qualitative definition of solubility?

    <p>The spontaneous interaction of 2 or more substances to form a homogeneous molecular dispersion</p> Signup and view all the answers

    What is the approximate solubility term for a substance that dissolves in 18 ml of water?

    <p>Freely soluble</p> Signup and view all the answers

    What is the equivalent weight of HNO3?

    <p>63</p> Signup and view all the answers

    What is the normality of a solution made by dissolving 8.5 g of H2SO4 in enough water to make 500 ml solution?

    <p>0.34</p> Signup and view all the answers

    What is the ratio of solute to solvent in a saturated solution that contains 100 g of solute and 300 g of solvent?

    <p>1:3</p> Signup and view all the answers

    What is the relationship between the normality and molarity of a solution?

    <p>The normality is never less than the molarity</p> Signup and view all the answers

    What is the normality of a 3 M H2SO4 solution?

    <p>6 N</p> Signup and view all the answers

    If 100 g of a saturated aqueous solution leaves a residue of 25 g after evaporation, what is the solubility of the anhydrous chemical?

    <p>1:3</p> Signup and view all the answers

    What is the normality of a 0.01 M H2SO4 solution?

    <p>0.02 N</p> Signup and view all the answers

    What is the weight of 100 mL of a saturated aqueous solution with a specific gravity of 1.15?

    <p>115 g</p> Signup and view all the answers

    If a saturated aqueous solution has a strength of 20% (w/w), what is the solubility of the active ingredient?

    <p>1:4</p> Signup and view all the answers

    What is the amount of solvent in a saturated solution that contains 25 g of solute and has a solubility of 1:3.6?

    <p>90 g</p> Signup and view all the answers

    What is the solubility of a substance if 100 mL of a saturated aqueous solution contains 25 g of the substance?

    <p>1:3.6</p> Signup and view all the answers

    What is the solubility of boric acid in water?

    <p>1 g in 4 g of water</p> Signup and view all the answers

    What is the percentage strength (w/w) of a saturated aqueous solution of boric acid?

    <p>5.26%</p> Signup and view all the answers

    What is the molar weight of Benzoic acid?

    <p>122 dalton</p> Signup and view all the answers

    What is the purpose of adding phenolphthalein indicator in the procedure?

    <p>To detect the end point of the titration</p> Signup and view all the answers

    What is the equivalent weight of salicylic acid in terms of 0.1 N NaOH?

    <p>0.0138 gm</p> Signup and view all the answers

    What is the formula to calculate the solubility (%) of an acid?

    <p>mls of titrant X F X 20</p> Signup and view all the answers

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