Podcast
Questions and Answers
What is the usual maintenance dose of febuxostat?
What is the usual maintenance dose of febuxostat?
- 100-200 mg/day
- 250-300 mg/day
- 800-900 mg/day
- > 300 mg/day (correct)
What is the recommended hydration level to prevent kidney stones when taking probenecid?
What is the recommended hydration level to prevent kidney stones when taking probenecid?
- > 2L of water (correct)
- No specific hydration level is recommended
- > 1L of water
- > 3L of water
What is the primary goal of HLA-B*5801 genotyping before initiating allopurinol?
What is the primary goal of HLA-B*5801 genotyping before initiating allopurinol?
- To rule out other underlying conditions
- To identify risk of allopurinol-induced SCARs (correct)
- To predict treatment response
- To determine optimal dosing
What is the initial dose of probenecid for patients with gout?
What is the initial dose of probenecid for patients with gout?
What is the maximum dose of febuxostat in patients with normal renal function?
What is the maximum dose of febuxostat in patients with normal renal function?
What is the time frame in which severe cutaneous adverse reactions (SCARs) most commonly occur after initiating allopurinol?
What is the time frame in which severe cutaneous adverse reactions (SCARs) most commonly occur after initiating allopurinol?
What is the primary cause of over-production of uric acid?
What is the primary cause of over-production of uric acid?
A patient wakes up with severe pain in the big toe joint. What is the likely diagnosis?
A patient wakes up with severe pain in the big toe joint. What is the likely diagnosis?
What is the diagnostic test for gout?
What is the diagnostic test for gout?
What is the goal of treatment in gout?
What is the goal of treatment in gout?
What is the normal serum uric acid level in women?
What is the normal serum uric acid level in women?
What is the treatment target for urate lowering therapy in tophaceous gout?
What is the treatment target for urate lowering therapy in tophaceous gout?
What is the name of the enzyme that breaks down hypoxanthine and guanine to form nucleic acids?
What is the name of the enzyme that breaks down hypoxanthine and guanine to form nucleic acids?
What is the purpose of prophylaxis in gout management?
What is the purpose of prophylaxis in gout management?
What is the name of the crystal that is deposited in the joints of patients with gout?
What is the name of the crystal that is deposited in the joints of patients with gout?
What is the term for the period between gout flares?
What is the term for the period between gout flares?
What is the reason routine genotyping is not done for allopurinol-induced SCAR?
What is the reason routine genotyping is not done for allopurinol-induced SCAR?
Which of the following medications increases the risk of bone marrow suppression when used with allopurinol?
Which of the following medications increases the risk of bone marrow suppression when used with allopurinol?
What is the purpose of initiating ULT with anti-inflammatory prophylaxis when starting allopurinol?
What is the purpose of initiating ULT with anti-inflammatory prophylaxis when starting allopurinol?
Which of the following is NOT a drug interaction with allopurinol?
Which of the following is NOT a drug interaction with allopurinol?
What is the typical dose of colchicine used for prophylaxis against acute flares when starting allopurinol?
What is the typical dose of colchicine used for prophylaxis against acute flares when starting allopurinol?
Which of the following patient groups is at higher risk of allopurinol-induced SCAR?
Which of the following patient groups is at higher risk of allopurinol-induced SCAR?
What is the recommended action when considering alternative antihypertensive therapy for gout patients?
What is the recommended action when considering alternative antihypertensive therapy for gout patients?
Which type of medication has a uricosuric effect and can be considered for gout patients?
Which type of medication has a uricosuric effect and can be considered for gout patients?
What should not be stopped or modified in gout patients despite its anti-uricosuric effect?
What should not be stopped or modified in gout patients despite its anti-uricosuric effect?
Which food-related information is relevant for gout patients?
Which food-related information is relevant for gout patients?
What is an important aspect to consider when taking a patient's medical history for gout?
What is an important aspect to consider when taking a patient's medical history for gout?
What is a recommended question to ask a patient during a gout consultation?
What is a recommended question to ask a patient during a gout consultation?
What is the primary underlying cause of gout?
What is the primary underlying cause of gout?
What is the term for the deposition of monosodium urate crystals in articular and periarticular tissues?
What is the term for the deposition of monosodium urate crystals in articular and periarticular tissues?
What is the goal of pharmacotherapy in managing gout?
What is the goal of pharmacotherapy in managing gout?
What is the term used to describe the heterogeneous clinical spectrum of diseases caused by monosodium urate crystals?
What is the term used to describe the heterogeneous clinical spectrum of diseases caused by monosodium urate crystals?
What is the learning objective related to the pharmacotherapy approach in gout?
What is the learning objective related to the pharmacotherapy approach in gout?
What is the common term used to describe the most common location of gout attacks?
What is the common term used to describe the most common location of gout attacks?
Flashcards are hidden until you start studying
