Questions and Answers
What is the usual maintenance dose of febuxostat?
> 300 mg/day
What is the recommended hydration level to prevent kidney stones when taking probenecid?
> 2L of water
What is the primary goal of HLA-B*5801 genotyping before initiating allopurinol?
To identify risk of allopurinol-induced SCARs
What is the initial dose of probenecid for patients with gout?
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What is the maximum dose of febuxostat in patients with normal renal function?
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What is the time frame in which severe cutaneous adverse reactions (SCARs) most commonly occur after initiating allopurinol?
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What is the primary cause of over-production of uric acid?
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A patient wakes up with severe pain in the big toe joint. What is the likely diagnosis?
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What is the diagnostic test for gout?
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What is the goal of treatment in gout?
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What is the normal serum uric acid level in women?
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What is the treatment target for urate lowering therapy in tophaceous gout?
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What is the name of the enzyme that breaks down hypoxanthine and guanine to form nucleic acids?
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What is the purpose of prophylaxis in gout management?
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What is the name of the crystal that is deposited in the joints of patients with gout?
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What is the term for the period between gout flares?
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What is the reason routine genotyping is not done for allopurinol-induced SCAR?
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Which of the following medications increases the risk of bone marrow suppression when used with allopurinol?
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What is the purpose of initiating ULT with anti-inflammatory prophylaxis when starting allopurinol?
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Which of the following is NOT a drug interaction with allopurinol?
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What is the typical dose of colchicine used for prophylaxis against acute flares when starting allopurinol?
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Which of the following patient groups is at higher risk of allopurinol-induced SCAR?
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What is the recommended action when considering alternative antihypertensive therapy for gout patients?
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Which type of medication has a uricosuric effect and can be considered for gout patients?
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What should not be stopped or modified in gout patients despite its anti-uricosuric effect?
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Which food-related information is relevant for gout patients?
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What is an important aspect to consider when taking a patient's medical history for gout?
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What is a recommended question to ask a patient during a gout consultation?
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What is the primary underlying cause of gout?
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What is the term for the deposition of monosodium urate crystals in articular and periarticular tissues?
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What is the goal of pharmacotherapy in managing gout?
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What is the term used to describe the heterogeneous clinical spectrum of diseases caused by monosodium urate crystals?
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What is the learning objective related to the pharmacotherapy approach in gout?
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What is the common term used to describe the most common location of gout attacks?
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