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Questions and Answers
What is the primary focus of pharmaceutics?
What is the primary focus of pharmaceutics?
What is a significant reason for preparing solid dosage forms with fillers or diluents?
What is a significant reason for preparing solid dosage forms with fillers or diluents?
Why must drug substances and pharmaceutical ingredients be compatible?
Why must drug substances and pharmaceutical ingredients be compatible?
What is a key aspect of the labeling of pharmaceutical products?
What is a key aspect of the labeling of pharmaceutical products?
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Which storage condition is essential for maximizing the shelf life of a pharmaceutical product?
Which storage condition is essential for maximizing the shelf life of a pharmaceutical product?
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What does the Rx symbol represent in a prescription?
What does the Rx symbol represent in a prescription?
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Which component of the prescription includes the medication name and dosage?
Which component of the prescription includes the medication name and dosage?
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What is the purpose of the Subscription in a prescription?
What is the purpose of the Subscription in a prescription?
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Why are abbreviations and symbols commonly used in prescriptions?
Why are abbreviations and symbols commonly used in prescriptions?
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What does the term 'Signa' refer to in a prescription?
What does the term 'Signa' refer to in a prescription?
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What could be a consequence of misunderstandings related to prescription abbreviations?
What could be a consequence of misunderstandings related to prescription abbreviations?
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What is one major recommendation by the Joint Commission regarding prescriptions?
What is one major recommendation by the Joint Commission regarding prescriptions?
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Which organization has published a list of error-prone abbreviations and symbols?
Which organization has published a list of error-prone abbreviations and symbols?
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What is the primary solvent used in pharmaceutical formulations?
What is the primary solvent used in pharmaceutical formulations?
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Which type of solution is specifically intended for external application to the skin?
Which type of solution is specifically intended for external application to the skin?
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What distinguishes elixirs from syrups in pharmaceutical preparations?
What distinguishes elixirs from syrups in pharmaceutical preparations?
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Which of the following solutions is NOT commonly used for medicinal purposes?
Which of the following solutions is NOT commonly used for medicinal purposes?
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What is the intended use of irrigations in pharmaceutical practices?
What is the intended use of irrigations in pharmaceutical practices?
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Which solution is characterized as having a variable proportion of alcohol and may include artificial sweeteners?
Which solution is characterized as having a variable proportion of alcohol and may include artificial sweeteners?
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What is required for certain pharmaceutical solutions like injections and ophthalmic solutions?
What is required for certain pharmaceutical solutions like injections and ophthalmic solutions?
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What type of solutions contains clear, saturated solutions of volatile oils or other aromatic substances in water?
What type of solutions contains clear, saturated solutions of volatile oils or other aromatic substances in water?
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What is the primary purpose of adding a plasticizer to soft-shell gelatin capsules?
What is the primary purpose of adding a plasticizer to soft-shell gelatin capsules?
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What distinguishes enteric coated capsules from regular capsules?
What distinguishes enteric coated capsules from regular capsules?
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What is the intended effect of extended-release capsules?
What is the intended effect of extended-release capsules?
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How are pellets and implants typically administered in the body?
How are pellets and implants typically administered in the body?
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What is a common use for placebos in clinical research?
What is a common use for placebos in clinical research?
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What kind of substances do capsules generally contain aside from medication?
What kind of substances do capsules generally contain aside from medication?
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What defines lozenges as a dosage form?
What defines lozenges as a dosage form?
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Which statement best describes the form of powders as medication?
Which statement best describes the form of powders as medication?
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What does the molality of a solution represent?
What does the molality of a solution represent?
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How is mole percent calculated?
How is mole percent calculated?
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What does Percent Weight-in-Volume (%w/v) express?
What does Percent Weight-in-Volume (%w/v) express?
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Which percent concentration is used by USP for solid mixtures?
Which percent concentration is used by USP for solid mixtures?
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What is the preferred method for the preparation of Syrup NF?
What is the preferred method for the preparation of Syrup NF?
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In %v/v concentration, what does it express?
In %v/v concentration, what does it express?
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Which statement about percent designations is true?
Which statement about percent designations is true?
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What is the role of a cotton pledget in the preparation of syrup via percolation?
What is the role of a cotton pledget in the preparation of syrup via percolation?
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Study Notes
Prescription components
- A prescription is a written order for medication from a healthcare professional to a pharmacist.
- Key components include:
- Prescriber information and signature
- Patient information
- Date prescription was written
- Rx symbol (the Superscription), meaning "take thou," "you take," or "recipe"
- Medication prescribed (the Inscription)
- Dispensing instructions to the pharmacist (the Subscription)
- Directions to the patient (the Signa)
- Special instructions
- Prescriptions commonly use abbreviations and symbols derived from Latin words and phrases.
- Misinterpretation of these can lead to medication errors.
- The Joint Commission requires healthcare organizations to standardize abbreviations, acronyms, and symbols.
- The Institute for Safe Medication Practices (ISMP) has published a list of error-prone abbreviations, symbols, and dose designations.
Dosage forms
- Each dosage form of a drug has unique physical and pharmaceutical characteristics.
- Pharmaceutics is the area of study concerned with the formulation, manufacture, stability, and effectiveness of dosage forms.
- Dosage forms are designed to deliver a specific amount of medication over a specific time frame.
Solutions
- Most drug substances are administered in milligram quantities, which are too small to be weighed accurately without a sensitive prescription or electronic analytical balance.
- Solutions are homogenous mixtures of two or more substances, typically a solute dissolved in a solvent.
- Water is the most common solvent in pharmaceuticals, but other liquids like alcohol, glycerin, and propylene glycol are also used.
- Depending on the route of administration, solutions can be categorized as:
- Oral solutions (mouth)
- Ophthalmic solutions (eye)
- Otic solutions (ear)
- Nasal solutions (nose)
- Rectal solutions
- Urethral solutions
- Epicutaneous solutions (skin)
- Injections
- Solutions used to bathe or flush open wounds or body cavities are termed irrigations.
- Certain solutions require sterility, such as those for injections, irrigations, and ophthalmic use.
Types of solutions
- Aromatic Waters: Clear, saturated solutions of volatile oils or other aromatic substances in water. Used orally, topically, or pharmaceutically.
- Collodions: Liquid preparations composed of pyroxylin dissolved in a solvent mixture (usually alcohol and ether) with or without added medicinal substances. Intended for external application to the skin. The solvent evaporates quickly, leaving a thin protective film.
- Elixirs: Sweetened, flavored, hydroalcoholic solutions intended for oral administration. Can be nonmedicated or medicated. Less sweet and less viscous than syrups. Better able to maintain both water-soluble and alcohol-soluble components in solution.
- Spirits: Alcoholic or hydroalcoholic solutions of volatile substances. Used orally for medicinal purposes or as flavoring agents.
Capsules
- Capsules are usually filled with powders, semisolids, or liquids.
- Capsules are intended to contain a specific quantity of medication.
- Capsules usually contain inert pharmaceutical substances, like fillers, disintegrants, and solubilizers.
- Gelatin capsules dissolve in the gastrointestinal fluids, releasing the medication.
- Enteric-coated capsules resist release in the stomach, allowing the medication to be released in the intestines.
- Extended-release capsules provide sustained release of medication over an extended period, typically 12 hours.
Implants or Pellets
- Small, sterile, solid dosage forms containing concentrated drug for implantation in the body.
- Continuously release medication over prolonged periods.
- Prepared by compression and implanted subcutaneously.
Lozenges
- Solid dosage preparations containing medicinal agents in a flavored, sweetened base.
- Dissolve or disintegrate slowly in the mouth, releasing medication for localized effects.
- Prepared by molding or compression.
Powders
- Dry mixtures of finely divided medicinal and nonmedicational agents intended for internal or external use.
Syrup NF
- Syrups are prepared in various ways, depending on the physicochemical characteristics of the substances entering the preparation.
- The preferred method for the preparation of Syrup NF is percolation, where a purified water or aqueous solution is allowed to pass slowly through a bed of crystalline sucrose, dissolving it and forming a syrup.
Concentration Units:
- Molality: The number of moles of solute in 1 kg of solvent.
- Mole Fraction: The number of moles of a component divided by the total number of moles in the solution.
- Mole Percent: Mole fraction multiplied by 100.
- Percent (percentage): Parts per hundred parts.
- Percent Weight-in-Weight (%w/w): The number of grams of a constituent in 100 g of solution.
- Percent Weight-in-Volume (%w/v): The number of grams of a constituent in 100 mL of solution. Used in prescription practice.
- Percent Volume-in-Volume (%v/v): The number of milliliters of a constituent in 100 mL of solution.
USP (United States Pharmacopeia)
- The USP indicates that the term "percent", when used in prescriptions without qualification, means:
- Percent weight in weight for mixtures of solids and semisolids.
- Percent weight in volume for solutions or suspensions of solids in liquids.
- Percent volume in volume for solutions of liquids in liquids.
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Description
Test your knowledge about the essential components of a prescription, including prescriber and patient information, medication details, and important instructions. Understand the significance of abbreviations and symbols in preventing medication errors. This quiz is designed for pharmacy students and professionals.