Pharmacology Quiz
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Questions and Answers

Which of the following statements about cholestyramine is not correct?

  • One of its most common side effects is bloating
  • Both a and d
  • Due to the potential for drug interactions, it should be taken at a different time from other required medications
  • It is a D2 receptor antagonist (correct)
  • It has a prokinetic effect and is used to increase gastrointestinal motility
  • What type of laxative is lactulose?

  • Stimulant laxative
  • Osmotic laxative (correct)
  • Stool surfactant agent
  • Bulk forming laxative
  • What is the mechanism of action of erythromycin when used for its prokinetic effect?

  • Agonist of cannabinoid receptors
  • Antagonist of neurokinin receptors
  • Agonist of motilin receptors (correct)
  • Both b and d
  • Antagonist of D2 receptors
  • Which of the following is not a characteristic of a household source epidemic?

    <p>Rapidly increasing quantity of patients</p> Signup and view all the answers

    Which of the following gastrointestinal organisms is transmitted through entering the bloodstream and then bodily secretions?

    <p>Typhoid fever</p> Signup and view all the answers

    Which of the following gastrointestinal infections is a zoonosis?

    <p>Leptospirosis</p> Signup and view all the answers

    Which of the following statements about cholestyramine is not correct?

    <p>It is a D2 receptor antagonist</p> Signup and view all the answers

    What is the mechanism of action of erythromycin when used for its prokinetic effect?

    <p>Both b and d</p> Signup and view all the answers

    What type of laxative is lactulose?

    <p>Osmotic laxative</p> Signup and view all the answers

    Which of the following is not a characteristic of a household source epidemic?

    <p>None of the above</p> Signup and view all the answers

    Which of the following gastrointestinal organisms is transmitted through entering the bloodstream and then bodily secretions?

    <p>Typhoid fever</p> Signup and view all the answers

    Which of the following gastrointestinal infections is a zoonosis?

    <p>Leptospirosis</p> Signup and view all the answers

    Study Notes

    Pharmacology

    • Cholestyramine is not a D2 receptor antagonist and does not have a prokinetic effect.
    • It can cause bloating and should be taken at a different time from other required medications.
    • Erythromycin has a prokinetic effect and is used to increase gastrointestinal motility by acting as an agonist of motilin receptors.
    • Lactulose is an osmotic laxative.

    Epidemiology

    • A household source epidemic is characterized by a slow course and high morbidity of children.
    • Typhoid fever is transmitted through entering the bloodstream and then bodily secretions.
    • Leptospirosis is a zoonosis, a gastrointestinal infection transmitted from animals to humans.
    • Foodborne infections are more likely to cause gastrointestinal epidemics in the summer and autumn.
    • The reduced incidence of esophageal cancer in China and high-income countries like the UK is due to economic progress and reduced smoking.
    • In northern Iran, the most important risk factor for esophageal cancer is betel quid chewing.
    • Golestan province has the highest age-standardized incidence rate of esophageal cancer in Iran.
    • Gastric cancer is among the top cancers in men in Iran and Afghanistan.
    • West Azerbaijan and Ardabil provinces have the highest incidence rates of gastric cancer in men.
    • Adenocarcinoma subtype intestinal is the most common histopathologic type of gastric cancer in men.

    Pathology

    • In Hirschsprung's disease, ganglion cells are not seen in the tissue, and it is more prevalent in boys.
    • Celiac disease is associated with villous atrophy of the duodenum, increased intraepithelial lymphocytes, and a risk of B cell lymphoma.
    • In ulcerative colitis, crypt destruction along with cryptitis and crypt abscesses are observed, limited to the mucosa.
    • Serrated polyps have a chance of malignant transformation and are more prevalent with age.
    • In a patient with colon cancer in the family and a malignant mass in the cecum, and her sister with endometrial adenocarcinoma, microsatellite instability is a possibility.
    • Invasive E. coli enteritis is more likely to be seen in a stool sample with many RBCs and WBCs.
    • Beetroot and vitamin C can cause a false negative result in the guaiac test.
    • In colon cancer, the depth of tissue involvement is a more important prognostic factor.
    • Herpes infection is characterized by multinucleated polykaryons and intracellular eosinophilic inclusions.
    • Achalasia is characterized by increased LES tone, aperistalsis, and functional obstruction.
    • Barrett's esophagus is diagnosed by endoscopy and biopsy, and most cases are not associated with esophageal squamous cell carcinoma.
    • Gastric mucosal damage can be caused by NSAID use, uremia, high altitude, and old age.
    • Cushing's ulcer is seen in intracranial disease.
    • In individuals with mutations in DNA repair genes, the conversion of large intestine tissue to cancerous tissue can take around 10 years.

    Pharmacology

    • Cholestyramine is not a D2 receptor antagonist and does not have a prokinetic effect.
    • It can cause bloating and should be taken at a different time from other required medications.
    • Erythromycin has a prokinetic effect and is used to increase gastrointestinal motility by acting as an agonist of motilin receptors.
    • Lactulose is an osmotic laxative.

    Epidemiology

    • A household source epidemic is characterized by a slow course and high morbidity of children.
    • Typhoid fever is transmitted through entering the bloodstream and then bodily secretions.
    • Leptospirosis is a zoonosis, a gastrointestinal infection transmitted from animals to humans.
    • Foodborne infections are more likely to cause gastrointestinal epidemics in the summer and autumn.
    • The reduced incidence of esophageal cancer in China and high-income countries like the UK is due to economic progress and reduced smoking.
    • In northern Iran, the most important risk factor for esophageal cancer is betel quid chewing.
    • Golestan province has the highest age-standardized incidence rate of esophageal cancer in Iran.
    • Gastric cancer is among the top cancers in men in Iran and Afghanistan.
    • West Azerbaijan and Ardabil provinces have the highest incidence rates of gastric cancer in men.
    • Adenocarcinoma subtype intestinal is the most common histopathologic type of gastric cancer in men.

    Pathology

    • In Hirschsprung's disease, ganglion cells are not seen in the tissue, and it is more prevalent in boys.
    • Celiac disease is associated with villous atrophy of the duodenum, increased intraepithelial lymphocytes, and a risk of B cell lymphoma.
    • In ulcerative colitis, crypt destruction along with cryptitis and crypt abscesses are observed, limited to the mucosa.
    • Serrated polyps have a chance of malignant transformation and are more prevalent with age.
    • In a patient with colon cancer in the family and a malignant mass in the cecum, and her sister with endometrial adenocarcinoma, microsatellite instability is a possibility.
    • Invasive E. coli enteritis is more likely to be seen in a stool sample with many RBCs and WBCs.
    • Beetroot and vitamin C can cause a false negative result in the guaiac test.
    • In colon cancer, the depth of tissue involvement is a more important prognostic factor.
    • Herpes infection is characterized by multinucleated polykaryons and intracellular eosinophilic inclusions.
    • Achalasia is characterized by increased LES tone, aperistalsis, and functional obstruction.
    • Barrett's esophagus is diagnosed by endoscopy and biopsy, and most cases are not associated with esophageal squamous cell carcinoma.
    • Gastric mucosal damage can be caused by NSAID use, uremia, high altitude, and old age.
    • Cushing's ulcer is seen in intracranial disease.
    • In individuals with mutations in DNA repair genes, the conversion of large intestine tissue to cancerous tissue can take around 10 years.

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    Pharmacology Past Paper PDF

    Description

    A short quiz on pharmacology, covering topics such as cholestyramine and erythromycin. Test your knowledge of these medications and their effects.

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