Pharmacology Overview Quiz

Instructions for the Exam

• Read the questions carefully and choose the best answer.
• If there are any alterations in the given options of the exam, choose the answer corresponding to that alteration
• Use black ballpoint pen only.

Pharmacology concepts

• Studying pharmacology involves analysis, assessment, and evaluation of circulating concentrations of drugs in serum, plasma, or whole blood.

• It encompasses the study of medications and their interactions with the body.

Pharmacokinetics

• The study of how medications move throughout the body.

• This includes absorption, distribution, metabolism, and excretion of medications.

• It describes chemical pathway responsible for the greatest portion of drug metabolism.

• It is the study of the relationship between drug concentration at the target site and the response of the tissues.

Pharmacodynamics

• The study of how medications produce their effects on the body.

• The study of the effects that affect the performance of a drug in the individual

• It describes the relation between drug dose and blood level.

• Describes the relationship between drug dose and drug blood levels.

• This defines the fraction of the drug dose that reaches the blood.

Drug Absorption

• A process by which medications move from the site of administration into the bloodstream.
• This often involves passive diffusion.

Drug Metabolism

• A process of drug chemical modifications to either activate or inactivate the drug, often through oxidation, reduction, or hydrolysis

• Includes conversions of active drugs to inactive drugs,

• Also includes the conversion of prodrugs into an active form,

• Includes the conversion of a hydrophobic drug to a hydrophilic drug,

• Includes the conversion of a drug to a nontoxic form,

• Includes all the processes mentioned above, except number 4.

Therapeutic Range

• A range of drug doses that produces therapeutic effects without significant side effects.

Important Concepts

• Pharmacokinetics is the study of what the body does to the drug.
• Pharmacodynamics is the study of what the drug does to the body.

Additional Concepts (Multiple choice questions)

• Amiodarone is a class III cardiac drug. It's used as a substitute for quinidine and is quickly absorbed orally.
• Vancomycin is a glycopeptide antibiotic, effective against various bacteria (Staphylococcus, Streptococcus, and Bacillus anthracis).
• Prozac is a psychoactive drug used to treat bipolar and other related disorders.
• An immunosuppressive drug, taken orally, is used to prevent host-versus-graft rejection, Sirolimus.
• A common analgesic and antipyretic drug, Aspirin, can lead to hepatotoxicity in overdose cases.
• Drugs used to treat acute schizophrenia include antipsychotics.
• Identifying single most important factors in determining the timing of peak and trough concentrations in a patient.

Additional Concepts (Multiple choice questions- continued)

• Important factor in determining the timing of peak and trough concentrations is the timing of specimen collection
• Quinidine and Lidocaine are not rapidly acting medications.
• The incorrect statement about classes of cardiac medications involves the statement that class IV cardiac drugs are calcium channel blockers. Class II cardiac medications are calcium channel blockers and Xylocaine is an example of a class II drug.

Test your knowledge on the fundamental concepts of pharmacology, including pharmacokinetics and pharmacodynamics. This quiz covers how drugs interact with the body, their movements, and their effects. Prepare to deepen your understanding of medication mechanisms.