Pharmacology of Zaleplon (Sonata)
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Questions and Answers

What type of drug is Sonata?

Non-benzodiazepines (sedative-hypnotics)

What is the prototype use of Sonata?

For ultra-short term treatment of insomnia

What are the trade and generic names for Sonata?

Trade: Sonata, Generic: Zaleplon

What is the mechanism of action of Sonata?

<p>Interacts with the gamma-aminobutyric acid (GABA) -A receptor</p> Signup and view all the answers

Which of the following are side effects of Sonata? (Select all that apply)

<p>Drowsiness</p> Signup and view all the answers

What does 'Adverse Effects' refer to in the context of Sonata?

<p>Up above</p> Signup and view all the answers

What critical information is associated with Sonata?

<p>Bedtime</p> Signup and view all the answers

Which statements about Zaleplon [Sonata] are true? (Select all that apply)

<p>Zaleplon [Sonata] should not be administered with cimetidine [Tagamet]</p> Signup and view all the answers

Study Notes

Sonata (Zaleplon) Overview

  • Class: Non-benzodiazepines, categorized as sedative-hypnotics used for sleep disorders.
  • Prototype drug for ultra-short-term treatment of insomnia.

Indications and Naming

  • Trade Name: Sonata
  • Generic Name: Zaleplon, indicating its pharmaceutical identity.

Mechanism of Action

  • Interacts with GABA-A receptors, enhancing the effects of the neurotransmitter GABA.
  • Influences the chloride channel ionophore complex to amplify inhibitory signals, promoting sleep.

Side Effects

  • Common side effects include:
    • Headache
    • Dizziness
    • Drowsiness
    • Nausea
    • Abdominal pain
    • Sleep-related behaviors, potentially leading to unusual activities during sleep.

Adverse Effects

  • Adverse effects are synonymous with the noted side effects; careful monitoring is essential.

Critical Information

  • Recommended for administration at bedtime to align with its sedative effects and promote sleep.

NCLEX Information

  • Important clinical considerations for nurses:
    • Zaleplon should not be given with cimetidine (Tagamet) due to potential drug interactions.
    • Knowledge of its interaction with GABA neurotransmitter essential for safe administration and patient education.

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Description

This quiz covers essential pharmacological information about Zaleplon, also known by its trade name Sonata. It explores its classification as a sedative-hypnotic, mechanism of action, indications, side effects, and critical administration information. Ideal for nursing students preparing for the NCLEX exam.

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