Pharmacology of the Respiratory Tract in Animals
48 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary site of action for central-acting antitussives?

  • Alveoli
  • Medulla (correct)
  • Vagus nerve
  • Brain stem
  • Which of the following antitussive agents is known to be 100 times more effective than codeine?

  • Dextromethorphan
  • Morphine
  • Hydrocodone
  • Butorphanol (correct)
  • What is a primary characteristic of dextromethorphan?

  • It produces significant analgesia.
  • It binds with opioid receptors.
  • Its mechanism has not been fully proven. (correct)
  • It is a central-acting antitussive.
  • How do anticholinergic drugs primarily cause bronchodilation?

    <p>By inhibiting vagal stimulus. (C)</p> Signup and view all the answers

    Which drug is effective as an antitussive in dogs but not in cats?

    <p>Hydrocodone (B)</p> Signup and view all the answers

    Which mechanism is involved in cough suppression for central-acting antitussives?

    <p>Depression of the cough center in the brain. (A)</p> Signup and view all the answers

    What is a common effect of high doses of Butorphanol?

    <p>Short-term analgesia (A)</p> Signup and view all the answers

    In terms of effectiveness and mechanism, how does hydrocodone compare to codeine?

    <p>More potent with a similar mechanism. (C)</p> Signup and view all the answers

    What is the primary function of mucolytic drugs?

    <p>To make the secretion more fluid and easier to eliminate. (D)</p> Signup and view all the answers

    Which of the following drugs is known to break disulfide bonds in mucus molecules?

    <p>Acetylcysteine (A)</p> Signup and view all the answers

    What is the primary concern regarding the effectiveness of expectorants?

    <p>Their effectiveness is questionable. (B)</p> Signup and view all the answers

    Which decongestant works primarily by reducing inflammation of the nasal mucosa?

    <p>Antihistamines (A)</p> Signup and view all the answers

    What is a primary effect of the drugs mentioned for nasal congestion?

    <p>Constriction of precapillary arterioles (A)</p> Signup and view all the answers

    What is a common issue associated with the use of potassium iodide as an expectorant?

    <p>It irritates the gastric mucosa, leading to increased bronchiolar secretion. (B)</p> Signup and view all the answers

    What unique characteristic does Bromhexine have compared to other mucolytics?

    <p>It may increase the concentration of certain antibiotics in the alveoli. (C)</p> Signup and view all the answers

    Which of the following antibiotics is used effectively in the respiratory tract?

    <p>Doxycycline (C)</p> Signup and view all the answers

    Which anti-inflammatory drug is incorrectly matched with its use?

    <p>Montelukast - treats bacterial infections (C)</p> Signup and view all the answers

    What is a notable side effect of sympathomimetics when used as decongestants?

    <p>Poor tolerance when administered as nasal sprays. (C)</p> Signup and view all the answers

    Which glucocorticoid is noted for being an inhaled option for animals?

    <p>Fluticasone (C)</p> Signup and view all the answers

    What therapeutic effect does Guaifenesin have in veterinary medicine?

    <p>It has little efficacy and is mainly for inducing muscle relaxation. (B)</p> Signup and view all the answers

    What is a characteristic of leukotriene receptor antagonists?

    <p>They are potent bronchoconstrictors (C)</p> Signup and view all the answers

    What is the role of NSAIDs like flunixin meglumine in respiratory diseases?

    <p>To alleviate inflammatory respiratory problems (B)</p> Signup and view all the answers

    Which treatment option is indicated for the stabilization of mast cells in animals with asthma?

    <p>Cromolyn (C)</p> Signup and view all the answers

    What is the primary clinical use of sympathomimetics/ß-adrenergic agonists?

    <p>Short-term relief of bronchospasm (C)</p> Signup and view all the answers

    Which statement is true regarding the administration of inhaled glucocorticoids in animals?

    <p>A mask and spacer are required for effective delivery (D)</p> Signup and view all the answers

    What significant side effect is NOT associated with parenterally administered anticholinergic drugs?

    <p>Increased respiratory rate (A)</p> Signup and view all the answers

    Which medication is NOT considered a selective sympathomimetic/ß-adrenergic agonist?

    <p>Isoproterenol (C)</p> Signup and view all the answers

    What is a potential adverse effect of prolonged use of Clembuterol?

    <p>Increased airway inflammation (D)</p> Signup and view all the answers

    Which receptor primarily mediates bronchodilation in response to adrenergic stimulation?

    <p>β2-adrenergic receptor (B)</p> Signup and view all the answers

    What is the mechanism by which β2-adrenergic receptor activation leads to muscle relaxation in the lungs?

    <p>Inactivation of myosin light chain kinase (D)</p> Signup and view all the answers

    Which of the following adverse effects is associated with methylxanthines derivatives?

    <p>Muscle tremors (C)</p> Signup and view all the answers

    What effect can overdose of selective β2-agonists have due to their action on β1-receptors?

    <p>Tachycardia (D)</p> Signup and view all the answers

    Which of the following medications is known for its anti-inflammatory effects at lower concentrations?

    <p>Theophylline (D)</p> Signup and view all the answers

    What property of selective β2-agonists aids in increasing mucociliary clearance in the respiratory tract?

    <p>Increasing ciliary beat frequency (D)</p> Signup and view all the answers

    What is a significant risk associated with the use of selective β2 agonists in cats?

    <p>Increased airway inflammation (D)</p> Signup and view all the answers

    Which of the following medications is used for the acute and emergency treatment of bronchoconstriction?

    <p>Epinephrine (C)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of mast cell stabilization by β2-agonists?

    <p>Increased systemic vascular resistance (C)</p> Signup and view all the answers

    Why are the effects of anticholinergics limited for chronic use?

    <p>They produce significant side effects (A)</p> Signup and view all the answers

    What is one of the mechanisms by which methylxanthines induce bronchodilation?

    <p>Blocking degradation of cyclic AMP (D)</p> Signup and view all the answers

    What role do α1-adrenergic receptors play in respiratory function?

    <p>Mediating airway muscle contraction in some species (D)</p> Signup and view all the answers

    What is a common side effect of sildenafil?

    <p>Increased gastric acid secretion (B)</p> Signup and view all the answers

    Which condition is sildenafil primarily used to treat?

    <p>Pulmonary hypertension (C)</p> Signup and view all the answers

    What is the mechanism of action of sildenafil?

    <p>Enhances cyclic GMP levels (C)</p> Signup and view all the answers

    Which of the following drug interactions should be monitored with sildenafil?

    <p>Inhibition of CYP450 enzymes (B)</p> Signup and view all the answers

    What effect does doxapram have when administered intravenously to dogs?

    <p>Increases respiratory rate (A)</p> Signup and view all the answers

    What is a notable application of doxapram in veterinary medicine?

    <p>Facilitate evaluation of laryngeal paralysis (A)</p> Signup and view all the answers

    Which animal is sildenafil NOT effective in treating pulmonary hypertension?

    <p>Horses (D)</p> Signup and view all the answers

    What is an important consideration when using doxapram?

    <p>It does not affect a paralyzed larynx (B)</p> Signup and view all the answers

    Study Notes

    Pharmacology of the Respiratory Tract

    • The presentation covers various medications used to treat respiratory issues in animals.
    • It includes discussions on anatomy and physiology of the respiratory system, control of respiratory secretions, antibiotics, cough suppressants, bronchodilators, and anti-inflammatory drugs.
    • Various medications such as Sildenafil, Doxapram, and inhalation therapy are mentioned.
    • Mucolytic drugs, expectorants, and decongestants are also part of the treatment, aiming to control respiratory secretions.
    • Different classes of drugs are detailed including antibiotics (Cephalosporins, Trimethoprim + Sulfadiazine, Amoxicillin, Amoxicillin + clavulamic acid, Doxycycline, Fluoroquinolones) and Glucocorticoids (Prednisolone, Prednisone, Fluticasone).
    • Non-steroidal anti-inflammatory drugs (NSAIDs) such as Flunixin meglumine are also considered for treatment.
    • Different cough suppressants such as morphine, codeine, hydrocodone, butorphanol, and Tramadol are reviewed.
    • Bronchodilators, including parasympatholytics/anticholinergics, sympathomimetics/β-adrenergic agonists, and methyxanthines derivatives are also discussed.
    • Specific drugs like atropine, glycopyrrolate, ipratropium, epinephrine, ephedrine, isoproterenol, terbutaline, isoetarin, albuterol, clembuterol are highlighted.
    • The use and properties of inhalation therapy are also noted, specifying various devices and medications used in this therapy.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    This quiz covers the pharmacological agents used to treat respiratory conditions in animals. Topics include the anatomy and physiology of the respiratory system, various drug classes, and their mechanisms of action. Key medications such as bronchodilators, antibiotics, and anti-inflammatory drugs are discussed in detail.

    More Like This

    Veterinary Pharmacology Quiz
    5 questions

    Veterinary Pharmacology Quiz

    AstonishedSnake5020 avatar
    AstonishedSnake5020
    Respiratory System Pharmacology
    12 questions
    Respiratory pharm
    13 questions

    Respiratory pharm

    MomentousMorganite avatar
    MomentousMorganite
    Use Quizgecko on...
    Browser
    Browser